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| 1 | Resveratrol engages selective apoptotic signals in gastric adenocarcinoma cells显示文摘AIM: To investigate the intracellular apoptotic signals engaged by resveratrol in three gastric adenocarcinoma cancer cell lines, two of which (AGS and SNU-1) express p53 and one (KATO-Ⅲ) with deleted p53. METHODS: Nuclear fragmentation was used to quanti- tate apoptotic cells; caspase activity was determined by photometric detection of cleaved substrates; formation of oxidized cytochrome C was used to measure cytochrome C activity, and Western blot analysis was used to determine protein expression. RESULTS: Gastric cancer cells, irrespective of their p53 status, responded to resveratrol with fragmentation of DNA and cleavage of nuclear lamins A and B and PARP. Resveratrol, however, has no effect on mitochondria-associated apoptotic proteins Bcl-2, Bcl- xl, Bax, Bid or Smac/Diablo, and did not promote sub- cellular redistribution of cytochrome C, indicating that resveratrol-induced apoptosis of gastric carcinoma cells does not require breakdown of mitochondrial membrane integrity. Resveratrol up-regulated p53 protein in SNU-1 and AGS cells but there was a difference in response of intracellular apoptotic signals between these cell lines. SNU-1 cells responded to resveratrol treatment with down-regulation of survivin, whereas in AGS and KATO- Ⅲ cells resveratrol stimulated caspase 3 and cytochrome C oxidase activities. CONCLUSION: These findings indicate that even within a specific cancer the intracellular apoptotic signals engaged by resveratrol are cell type dependent and suggest that such differences may be related to differentiation or lack of differentiation of these cells. | William L Riles Jason Erickson Sanjay Nayyar Mary Jo Atten Bashar M Attar Oksana Holian | 2006 | World Journal of Gastroenterology2006，12，35： | 8 |
| 2 | Differential Sensitivity of Macrocarpa and Microcarpa Types of Chickpea (Cicer arietinum L.) to Water Stress: Association of Contrasting Stress Response with Oxidative Injury显示文摘Chickpea (Cicer arietinum L.) 是特别地敏感的在它的繁殖阶段浇应力并且在水应力的条件下面,将放弃花和豆荚,因此减少收益潜力。有 chickpea 的二种类型:(i) Macrocarpa (Kabuli ) 它有大,击打塑造头的、轻棕色的种子;并且(ii ) Microcarpa (Desi ) 它有小、尖、黑暗褐的种子。相对说, Kabuli 被报导了更敏感比 Desi 浇应力。与对比敏感流水联系的内在的机制在新陈代谢的水平强调井没被理解。我们假设了一个原因因为在 chickpea 的二种类型的形成对照的水压力敏感可以是在氧化损害的一个变化。在现在的学习,两种类型的植物是为 14 d 在繁殖舞台强调的水。由于压力, Kabuli 类型与为 Desi 类型观察的 64% 减小相比在控制上在种子产量展出了 80% 减小。在叶水潜力(w) 的减少与 Desi 类型相比在 Kabuli 是更快的。在水压力时期的结束, w 被归结为 ? 2.9 并且 ? 分别地,没有他们之间的任何重要差别,在 Desi 和 Kabuli 的 3.1 MPa 打字。在应力的最后一天, Kabuli 比 Desi 经历了 20% 更多的膜损害。叶绿素内容和光合的率与 Kabuli 相比在 Desi 是显著地更大的。malondialdehyde 和 H2O2 内容与 Desi 相比在在 Kabuli 的水压力的结束是显著地更高的,显示在前者的更大的氧化应力。抗氧化剂的层次例如维生素酸和谷胱甘肽,比 Kabuli 在 Desi 是显著地更高的。, Superoxide dismutase 和过氧化氢酶活动没在第 10 天, ascorbate peroxidase 的活动, dehydroascorbate reductase,和谷胱甘肽 reductase 在 chickpea 的二种类型之间显著地不同在 Desi 是更高的。这些调查结果显示在 Desi 类型的更大的应力公差可以被归功于到它维持更好的水地位的优异能力,它导致更少的氧化损坏。另外,实验室研究由使 chickpea 的两种类型遭到到聚乙烯的类似的层次进行了导致乙二醇的水应力并且到 10 .mol/L abscisic,酸显示了 Desi 类型的一个更大的能力比 Kabuli 类型处理氧化应力。 | Harsh Nayyar Smita Singh Satwinder Kaur Sanjeev Kumar Hari D. Upadhyaya | 2006 | Journal of Integrative Plant Biology2006，48，11： | 6 |
| 3 | MADCR:Mobility Aware Dynamic Clustering-Based Routing Protocol in Internet of Vehicles显示文摘Internet of Vehicles(IoV)is an evolution of the Internet of Things(IoT)to improve the capabilities of vehicular ad-hoc networks(VANETs)in intelligence transport systems.The network topology in IoV paradigm is highly dynamic.Clustering is one of the promising solutions to maintain the route stability in the dynamic network.However,existing algorithms consume a considerable amount of time in the cluster head(CH)selection process.Thus,this study proposes a mobility aware dynamic clustering-based routing(MADCR)protocol in IoV to maximize the lifespan of networks and reduce the end-to-end delay of vehicles.The MADCR protocol consists of cluster formation and CH selection processes.A cluster is formed on the basis of Euclidean distance.The CH is then chosen using the mayfly optimization algorithm(MOA).The CH subsequently receives vehicle data and forwards such data to the Road Side Unit(RSU).The performance of the MADCR protocol is compared with that ofAnt Colony Optimization(ACO),Comprehensive Learning Particle Swarm Optimization(CLPSO),and Clustering Algorithm for Internet of Vehicles based on Dragonfly Optimizer(CAVDO).The proposed MADCR protocol decreases the end-toend delay by 5–80 ms and increases the packet delivery ratio by 5%–15%. | Sankar Sennan Somula Ramasubbareddy Sathiyabhama Balasubramaniyam Anand Nayyar Chaker Abdelaziz Kerrache Muhammad Bilal | 2021 | China Communications2021，18，7： | 4 |
| 4 | Soil microbial quality associated with yield reduction in continuous-pea显示文摘 | Atul Nayyar Chantal Hamel Guy Lafond Bruce D. Gossen Keith Hanson Jim Germida | 2009 | Applied Soil Ecology2009，，1： | 2 |
| 5 | System Performance of Wireless Sensor Network Using LoRa–Zigbee Hybrid Communication显示文摘Wireless sensor network(WSN)is considered as the fastest growing technology pattern in recent years because of its applicability in varied domains.Many sensor nodes with different sensing functionalities are deployed in the monitoring area to collect suitable data and transmit it to the gateway.Ensuring communications in heterogeneous WSNs,is a critical issue that needs to be studied.In this research paper,we study the system performance of a heterogeneous WSN using LoRa–Zigbee hybrid communication.Specifically,two Zigbee sensor clusters and two LoRa sensor clusters are used and combined with two Zigbee-to-LoRa converters to communicate in a network managed by a LoRa gateway.The overall system integrates many different sensors in terms of types,communication protocols,and accuracy,which can be used in many applications in realistic environments such as on land,under water,or in the air.In addition to this,a synchronous management software on ThingSpeak Web server and Blynk app is designed.In the proposed system,the token ring protocol in Zigbee network and polling mechanism in LoRa network is used.The system can operate with a packet loss rate of less than 0.5%when the communication range of the Zigbee network is 630 m,and the communication range of the LoRa network is 3.7 km.On the basis of the digital results collected on the management software,this study proves tremendous improvements in the system performance. | Van-Truong Truong Anand Nayyar Showkat Ahmad Lone | 2021 | Computers, Materials & Continua2021，，8： | 2 |
| 6 | 战争与和平 绝望与希望——“九一一”后亚洲知识分子的再定位显示文摘“亚洲交流(ARENA)”在二○○二年五月召开座谈会,邀请亚洲十五名学者参加,座谈内容包括:“九一一”的现实与象征涵义,趋势与挑战,希望的声音,面向未来。以下座谈摘要由刘健芝编译。 | 刘健芝 Chandra Muzaffar 武藤一羊 Abdul Nayyar Joseph Gerson Conrad de Quiros Max de Mesa Aditya Nigam 许兆麟 李贞玉 Chandra Muzaffar Harsh Sethi Jeannie Manipon 梁兰周 | 2002 | 读书2002，，9： | 2 |
| 7 | Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma. New trends and future opportunities显示文摘 | Ruy J. Cruz Sarangarajan Ranganathan George Mazariegos Kyle Soltys Navdeep Nayyar Qing Sun Geoffrey Bond Peter H. Shaw Kimberly Haberman Lakshmanan Krishnamurti Abhinav Humar Rakesh Sindhi | 2012 | Surgery2012，，： | 2 |
| 8 | Th17 cells and IL - 17 receptor signaling are essential for mucosal host defense against oral candidiasis 显示文摘 | Conti HR Shen F Nayyar N | 2009 | J Exp Med2009，206，2： | 1 |
| 9 | Acute pancreatitis in children显示文摘 | DeBanto JR Goday PS Pedroso MR Iftikhar R Fazel A Nayyar S | 2002 | Am J Gastroenterol2002，97，7： | 1 |
| 10 | Mortality rates among prevalent hemodialysis patients in Beijing: a compari- son with USRDS data显示文摘 | Cheng X Nayyar S Wang M | 2013 | Nephrol Dial Transplant2013，28，3： | 1 |
| 11 | Soil microbial quality associ- ated with yield reduction in continuous-pea显示文摘 | Nayyar A Hamel C Lafond G | 2009 | Applied Soil Ecolo- gy2009，43，1： | 1 |
| 12 | Asdrssment of metabolites and AhR and CYP1A1 mRNA expression subsequent to prenatal exposure to inhaled benzoapyrene显示文摘 | Wu J Ramesh A Nayyar T | 2003 | Int J Dev Neurosci2003，21，6： | 1 |
| 13 | Transformative Capability: Continual Structuring by Inter Temporal Technology Transfer 显示文摘 | GAARUD R NAYYAR P R | 1994 | Strategic Management Journal1994，15，5： | 1 |
| 14 | Assessment of metabolites and AhR and CYP1 A1 mRNA expression subsequent to prenatal exposure to inhaled benzo (a) pyrene 显示文摘 | Wu J Ramesh A Nayyar T | 2003 | Int J Dev Neurosci2003，21，6： | 1 |
| 15 | Brain natriuretic peptide in diagnosis and treatment of heart failure显示文摘 | Bhatia V Nayyar P Dhindsa S | 2003 | J Postgrad Med2003，49，2： | 1 |
| 16 | Monitoring the operationally tolerant liver allograft recipient显示文摘 | Castellaneta A Thomson AW Nayyar N | 2010 | Curr Opin Organ Transplant2010，15，1： | 1 |
| 17 | Transformative capacity: Continual structuring by intertemporal technology transfer显示文摘 | Garud R Nayyar P R | 1994 | Strate- gic Management Journal1994，15，5： | 1 |
| 18 | Inhaled benzoapyrene impairs long-term potentiation in the F1 generation rat dentate gyrus显示文摘 | Wormley D D Chirwa S Nayyar T | 2004 | Cell Mol Biol2004，50，6： | 1 |
| 19 | Upgrading of Gleason score onradical prostatectomy specimen compared to the pre-operative needlecore biopsy:an Indian experience显示文摘 | Nayyar R Singh P Gupta N P | 2010 | Indian J Urol2010，26，1： | 1 |
| 20 | Transmesocolic robot- assisted pyeloplasty:single center experience 显示文摘 | Gupta NP Mukheijee S Nayyar R | 2009 | J Endourol2009，23，： | 1 |
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