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    题名 作者 年代 出处 被引量
1CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells显示文摘Xiaojuan Liu Yongping Zhang Chen Cheng Albert W Cheng Xingying Zhang Na Li Changqing Xia Xiaofei Wei Xiang Liu Haoyi Wang 2017Cell Research2017,27,1:40
2Structural basis for blocking PD-l-mediated immune suppression by therapeutic antibody pembrolizumab显示文摘Zhenkun Na Siok Ping Yeo Sakshibeedu R Bharath Matthew W Bowler Esra Ballkci Cheng-I Wang Haiwei Song 2017Cell Research2017,27,1:10
3酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB 2021中华高血压杂志2021,29,2:9
4Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu 2011Cell Research2011,21,5:3
5Corrosion resistance of tannic acid,d-limonene and nano-ZrO_(2)modified epoxy coatings in acid corrosion environments显示文摘The protection of rusted carbon steel in acid corrosion environments is of great significance for equipment to keep safe operation.In this work,we presented a method to protect the rusted steel by ru st conversion treatment and epoxy coating.Tannic acid was selected as rust conversion agent.Tannic acid,D-limonene and nano-ZrO_(2)were used to improve the corrosion resistance of epoxy coatings.The Raman spectra,Xray diffraction and 3 D confocal images were used to characterize the rust conversion reaction.Ad hesion test showed that the loss of wet adhesion of the optimal coating was relatively low due to the addition of tannic acid,limonene and nano-ZrO(2).The corrosion resistance of five different coatings was investigated by scanning electron microscopy(SEM)and electrochemical analysis.Results show that after 264 h acid immersion,the low frequency resistance of the optimal coating consisting of rust conversion treatment and additives is 10^(7)Ωcm^(2),three orders magnitude higher than that of the pristine coating.Moreover,SEM indicates that the optimal coating possesses a smooth surface and an unbroken interface between substrate and coating.Accordingly,the corrosion-resistant mechanism of the hybrid coating is proposed.Junwei Chang Zhenyu W ang En-hou Han Xinlei Liang Gang Wang Zuyao Yi Na Li 2021Journal of Materials Science & Technology2021,,6:3
6Hydrogels in pharmaceutical formulation显示文摘Peppas NA Bures P Leobandung W 2000Eur J Pharm Biopharm2000,50,1:2
7Handling zero values in the logarithmic mean divisia index decomposition approach 显示文摘Ang B W Na Liu 2007Energy Policy2007,,35:1
8Differential response of porphyromonas gingivalis to varying levels and duration of hydrogen peroxide-induced oxidative stress 显示文摘McKenzie RM Johnson NA Aruni W 2012Mi- crobiology2012,158,10:1
9N20 and NO emissions from co-firing MSW with coals in pilot scale CFBC显示文摘Li Z W Lu Q G Na Y J 2004Fuel Processing Technology2004,85,14:1
10High catalytic activity of Pd2+-exchanged mesoporous sodalite and NaA zeolite for bulky aryls coupling:reusability under aerobic condition显示文摘Choi M Lee D H Na K Yu B W Ryoo R 0,,20:1
11Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monodonal antibodies by enhancing recovery of β-cells显示文摘Sherey NA Chen W Kushner JA 0,,:1
12Activation of Notch-Mediated Protective Signaling in the Myocardium显示文摘Gude NA Emmanuel G Wu W 2008Circ Res2008,102,9:1
13Response surface method using vector projected sampling points显示文摘Kim S H Na S W 1997Structural Safety1997,19,1:1
14Molecular Characteristics Predict Clinical Outcomes: Prospective Trial Correlating Response to the EGFR Tyrosine Kinase Inhibitor Gefitinib with the Presence of Sensitizing Mutations in the Tyrosine Binding Domain of the EGFRGene 显示文摘Rizvi NA Rusch V Pao W 2011ClinCancerRes2011,17,10:1
15Corrison behavior of austenitic stainless steel as a function of methanol concentration for direct methanol fuel cell bipolar plate显示文摘Lixia W Bin K Na G 2014J Pow Sour2014,253,:1
16Global chemome study by LC coupled with DAD and ESI-Q-TOF MS of a comosite traditional Chinese medicine Qishenyiqi Dropping Pills 显示文摘WANG J NA W ZHAO H Z 2010Chromatographia2010,72,3:1
17Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats:a comparison with lentiviral vectors显示文摘Harvey AR Kamphuis W Eggers R Symons NA Blits B Niclou S et ol 2002Mol Cell Neurosci2002,21,1:1
18Rheological and electtrical properties of polypropylene composites containing functionalized multi-walled carbon nanotubes and comrpatibilizers显示文摘Lee Seung H w an Cho Eun Na Ri 0,,:1
19Ferromagnetism of MnO and Mn3O4 nanowires显示文摘NA C W HAND S KIM D S 0,,14:1
20Pillared MFI zeolite nanosheets of a single-unit-cell thickness显示文摘Na K Choi M Park W 2010J Am Chem Soc2010,131,12:1
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