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| 1 | Achalasia: A review of clinical diagnosis, epidemiology,treatment and outcomes显示文摘Achalasia is a neurodegenerative motility disorder of the oesophagus resulting in deranged oesophageal peristalsis and loss of lower oesophageal sphincter function.Historically,annual achalasia incidence rates were believed to be low,approximately 0.5-1.2 per 100000.More recent reports suggest that annual incidence rates have risen to 1.6 per 100000 in some populations.The aetiology of achalasia is still unclear but is likely to be multi-factorial.Suggested causes include environmental or viral exposures resulting in inflammation of the oesophageal myenteric plexus,which elicits an autoimmune response.Risk of achalasia may be elevated in a sub-group of genetically susceptible people.Improvement in the diagnosis of achalasia,through the introduction of high resolution manometry with pressure topography plotting,has resulted in the development of a novel classification system for achalasia.This classification system can evaluate patient prognosis and predict responsiveness to treatment.There is currently much debate over whether pneumatic dilatation is a superior method compared to the Heller’s myotomy procedure in the treatment of achalasia.A recent com-parative study found equal efficacy,suggesting that patient preference and local expertise should guide the choice.Although achalasia is a relatively rare condition,it carries a risk of complications,including aspiration pneumonia and oesophageal cancer.The risk of both squamous cell carcinoma and adenocarcinoma of the oesophagus is believed to be significantly increased in patients with achalasia,however the absolute excess risk is small.Therefore,it is currently unknown whether a surveillance programme in achalasia patients would be effective or cost-effective. | Orla M O'Neill Brian T Johnston Helen G Coleman | 2013 | World Journal of Gastroenterology2013，19，35： | 26 |
| 2 | Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomograph显示文摘 | RAFF G L GALLAGHER M J NEILL W W | 2005 | J Am Coll Cardiol2005，46，： | 1 |
| 3 | Measurements of aerobic metabolism of a school of horse mackerel at different swimming speeds显示文摘 | Soofiani N M and O'Neill F G | 1996 | Journal of Fish Biology1996，49，5： | 1 |
| 4 | FOXM1 is adownstream target of Glil in basal cell carcinomas 显示文摘 | Teh M T Wong S T Neill G W | 2002 | Cancer Res2002，62，16： | 1 |
| 5 | Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria 显示文摘 | BIAGINI G A VIRIYAVEJAKUL O O’NEILL P M | 2006 | Antimicrob Agents Chemother2006，50，： | 1 |
| 6 | The Value of the World's Ecosystem Services and Natural Capital显示文摘 | Costanza R d'Arge R de Groot R Farberk S Grasso M Hannon B Limburg K Naeem S O'Neill R V Paruelo J Raskin R G Suttonkk P van den Belt M | | 0，，6630： | 1 |
| 7 | Randomized trial comparing holmium laser enucleation of prostate with plasmakinetic enucleation of prostate for treatment of benign prostatic hyperplasia 显示文摘 | NEILL M G GILLING P J KENNETT K M | 2006 | Urology2006，68，5： | 1 |
| 8 | Endovascular treatment of traumatic dural sinus thrombosis:case report显示文摘 | Kuether T O'Neill Nesbit G M | 1998 | Neurosurgery1998，42，5： | 1 |
| 9 | Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4^sup +^ T cell loss is associated with double-negative T cells显示文摘 | Milush Jeffrey M Mir Kiran D Sundaravaradan Vasudha Gordon Shari N Engram Jessica Cano Christopher A Reeves Jacqueline F Anton Elizabeth O’Neill Eduardo Butler Eboneé Hancock Kathy Cole Kelly S Brenchley Jason M Else James G Silvestri Guido | 2011 | Journal of Clinical Investigation2011，，3： | 1 |
| 10 | MDM2 SNP309 is as- sociated with high grade node positive breast turnouts and is in linkage disequilibrium with a novel MDM2 intronl polymorphism 显示文摘 | Paulin FE O'Neill M McGregor G | 2008 | BMC Cancer2008，8，： | 1 |
| 11 | Young children's motor skill performance:relationships with activity types and parent perception of athletic competence显示文摘 | O'Neill J R Williams H G Pfeiffer K A Dowda M Mciver K L Brown W H | 2014 | Journal of science and medicine in sport/Sports Medicine Australia2014，17，6： | 1 |
| 12 | Surgical experience with thirteen conjoined twins显示文摘 | O'NEILL J A HOLCOMB G M SCHNAUFER L | 1988 | Ann Surg1988，208，3： | 1 |
| 13 | Evaluation of corn grain yield and water use efficiency using subsurface drip irrigation 显示文摘 | Pablo R G O'Neill M K McCaslin B D | 2007 | Journal of Sustainable Agriculture2007，30，1： | 1 |
| 14 | Borderline tumors of the ovary:CT and MRI features and tumor markers in differentiation from stage Ⅰ disease显示文摘 | DeSouza N M O' Neill R McIndoe G A | 2005 | AJR Am J Roentgenol2005，184，3： | 1 |
| 15 | The emerging role of metabolic regulation in the functioning of Toll-like receptors and the NOD-like receptor Nlrp3显示文摘 | TANNAHILL G M O'NEILL L A | 2011 | FEBS Lett2011，585，11： | 1 |
| 16 | Diagnostic accuracy of noninvasive eoronaryangiography using 64-slice computed tomography显示文摘 | Raft G L Gallaugher M J O 'Neill W W | 2005 | J Am Coll Cardiol2005，46，7： | 1 |
| 17 | Pathogenesis of porcine cireovirus:experimentai infection of colostrums deprived piglet and experimental infections of eolostrums deprived piglets and examination of pig fetal material显示文摘 | Allan G M Mc Neill Y F Cassidyj P | 1995 | Vet Microbial1995，44，1： | 1 |
| 18 | Diagnostic accura- cy of noninvasive coronary angiography using 64-slice spiral compu- ted tomography显示文摘 | Raff G L Gallagher M J O'Neill W W | 2005 | J Am Coll Cardiol2005，46，3： | 1 |
| 19 | A new animal model of endogenous depression: A summary of present findings显示文摘 | Vogel G Neill D Hagler M | 1990 | Neurosci Biobehav Rev1990，14，： | 1 |
| 20 | Secretory leucoprotease inhibitor impairs toll - like receptor 2 - and 4 -mediated responses in monocytic cells显示文摘 | Catherine M Greene Noel G McElvaney Shane J O' Neill | 2004 | Infection and immunity2004，72，6： | 1 |
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