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1Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013显示文摘Marie Ng Tom Fleming Margaret Robinson Blake Thomson Nicholas Graetz Christopher Margono Erin C Mullany Stan Biryukov Cristiana Abbafati Semaw Ferede Abera Jerry P Abraham Niveen M E Abu-Rmeileh Tom Achoki Fadia S AlBuhairan Zewdie A Alemu Rafael Alfonso 2014The Lancet2014,,:7
2Critical analysis of feeding jejunostomy following resection of upper gastrointestinal malignancies显示文摘AIM To assess nutritional recovery,particularly regarding feeding jejunostomy tube(FJT)utilization,following upper gastrointestinal resection for malignancy. METHODS A retrospective review was performed of a prospectively-maintained database of adult patients who underwent esophagectomy or gastrectomy(subtotal or total)for cancer with curative intent,from January 2001 to June 2014. Patient demographics,the approach to esophagectomy,the extent of gastrectomy,FJT placement and utilization at discharge,administration of parenteral nutrition(PN),and complications were evaluated. All patients were followed for at least ninety days or until death.RESULTS The 287 patients underwent upper GI resection,comprised of 182 esophagectomy(n=107 transhiatal,58.7%; n=56 Ivor-Lewis,30.7%)and 105 gastrectomy [n=63 subtotal(SG),60.0%; n=42 total(TG),40.0%]. 181 of 182 esophagectomy patients underwent FJT,compared with 47 of 105 gastrectomy patients(99.5% vs 44.8%,P < 0.0001),of whom most had undergone TG(n=39,92.9% vs n=8 SG,12.9%,P < 0.0001). Median length of stay was similar between esophagectomy and gastrectomy groups(14.7 d vs 17.1 d,P=0.076). Upon discharge,87 esophagectomy patients(48.1%)were taking enteral feeds,with 53(29.3%)fully and 34(18.8%)partially dependent. Meanwhile,20 of 39 TG patients(51.3%)were either fully(n=3,7.7%)or partially(n=17,43.6%)dependent on tube feeds,compared with 5 of 8 SG patients(10.6%),all of whom were partially dependent. Gastrectomy patients were significantly less likely to be fully dependent on tube feeds at discharge compared to esophagectomy patients(6.4% vs 29.3%,P=0.0006). PN was administered despite FJT placement more often following gastrectomy than esophagectomy(n=11,23.4% vs n=7,3.9%,P=0.0001). FJT-specific complications requiring reoperation within 30 d of resection occurred more commonly in the gastrectomy group(n=6),all after TG,compared to 1 esophagectomy patient(12.8% vs 0.6%,P=0.0003). Six of 7 patients(85.7%)who experienced tube-related complications required PN.CONCLUSION Nutritional recovery following esophagectomy and gastrectomy is distinct. Operations are associated with unique complication profiles. Nutritional supplementation alternative to jejunostomy should be considered in particular scenarios.Andrew M Blakely Saad Ajmal Rachel E Sargent Thomas T Ng Thomas J Miner 2017World Journal of Gastrointestinal Surgery2017,9,2:4
3Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes - Association analyses in 9,518 subjects显示文摘Owen, KR Groves, CJ Hanson, RL Knowler, WC Shuldiner, AR Elbein, SC Mitchell, BD Froguel,P Ng, MCY Chan, JC Jia, WP Deloukas, P Hitman, GA Walker, M Frayling, TM Hattersley, AT Zeggini, E McCarthy, MI 2007中国生物学文摘2007,21,11:2
4经导管动脉栓塞术治疗肝癌:最新临床证据显示文摘对不能接受根治性治疗如肝移植、肿瘤切除术或经皮射频消融术(radiofrequency ablation,RFA)的肝细胞肝癌(hepatocellular carcinoma,HCC)患者,经导管动脉化疗栓塞术(transarterial chemoembolization,TACE)或放疗栓塞术(transarterial radioembolization,TARE)是治疗的核心手段。近期研究证据显示:对于无血管侵犯、3 cm及以下单结节型HCC患者,TACE与肿瘤切除术及RFA后的5年总生存率相似。尽管已应用数十年,碘油(超液化碘油®,Lipiodol®Ultra Fluid,Guerbet,France)作为一种亲肿瘤性且不透射线的药物运输载体在肿瘤介入治疗中的地位依然重要。药物缓释微球(drug-eluting bead,DEB)是栓塞术中一种较新型的药物输送方式,既可维持药物浓度,也可持续释放抗癌药。现有三种DEB可供临床选择使用,即Tandem®(Celo Nova Biosciences Inc.),DC-Beads®(BTG,UK)和Hepa Sphere®(Bio Sphere Medical,Inc.,USA)。经动脉TARE已被证实可安全有效地运用于晚期肝癌及有肝血管侵犯的患者。两种放射性栓塞微粒可供临床选择使用,即SIR-Spheres®(Sirtex Medical Limited,Australia)和Thera Sphere®(BTG,UK)。本文总结肝癌经导管动脉治疗的关键临床试验。Yì-Xiáng J.Wáng Thierry De Baere Jean-Marc Idée Sébastien Ballet 邓敏 王毅翔 2015临床与病理杂志2015,35,7:2
5Algorithms for mining distance based outliers in large data sets 显示文摘E Knorr and R Ng 1998VLDB Conference Proceedings1998,,:2
6Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter 显示文摘Procko E Ferrin- O' Connell I Ng SL 2006Mol Cell2006,24,1:1
7Increased prevalence and analysis of risk factors for indinavir nephrolithiasis显示文摘 ANGEL JB FUTTER NG 2000J Urol2000,164,6:1
8hS1R2(SIRT1) functions as an NAD-dependent p53 deacetylase显示文摘Vaziri H Dessain S K Ng Eaton E 2001Cell2001,107,2:1
9Inhibition of Campylobacter coli and Campylobacter jejuni by antibio- tics used in selective growth media 显示文摘Ng L K Stiles M E Taylor D E 1985Journal of Clinical Microbiology1985,22,4:1
10Higher-order multivariate Markov chains and their applications显示文摘Ching W K Ng M K Fung E S 2008Linear Algebra and its Applications2008,428,2:1
11Pediatric standard and robot-assisted laparoseopie pyeloplasty: a comparative single institution study显示文摘Riaehy E Cost NG Defoor WR 2013J Urol2013,189,:1
12Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome 显示文摘Ng E K Hui D S Chan K C 2003Clin Chem2003,49,12:1
13Melanocytes and the microphthalmia transcription factor network 显示文摘Steingrimsson E Copeland NG Jenkins NA 2004Annual Review of Genetics2004,38,:1
14Requirement for the lymphocyte semaphorin, CD100, in the induction of antigenspecific T cells and the maturation of dendritic ceils 显示文摘Kumanogoh A Suzuki K Ch ' ng E 2002J lmmunol2002,169,3:1
15Geographic-time distribution of ambulance calls in Singapore:utility of geographic information system in ambulance deployment (CARE 3)显示文摘ONG M E NG F S OVERTON J 2009Ann Acad Med Singapore2009,38,3:1
16Effective Preconditioning Through Ordering Interleaved with Incomplete Factorization显示文摘Lee I Raghavan P Ng E G 2006SIAM Journal on Matrix Analysis and Applications2006,27,4:1
17Synthesis of continuous MOF-5 membranes on porous a- alumina substrates 显示文摘Liu Y Ng Z Khan E Jeong H K Ching C Lai Z 2009Microporous Mesoporous Materials2009,118,123:1
18Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas 显示文摘Sehummer M Ng W V Bumgarner R E 1999Gene1999,238,2:1
19p53 status, cellular recovery and cell cycle arrest as prognosticators of in vitro radiosensitivity in human pancreatic adenocarcinoma cell lines显示文摘Ng C E Banerjee S K Pavliv M 1999Int J Radiat Biol1999,75,11:1
20The Design and Planning of Cable Harness Assemblies显示文摘Ng F M Ritchie J M Simmons J E L 2001Journal of Engineering Manufacture:Part B2001,215,:1
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