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| 1 | Disease impact on the quality of life of children with inflammatory bowel disease显示文摘AIM To assess the impact of disease characteristics on the quality of life (QOL) in children with inflammatory bowel diseases(IBD).METHODS This was a cross-sectional study conducted at the First Department of Pediatrics of the University of Athens at the 'Aghia Sophia' Children's Hospital. Children diagnosed with Crohn's disease (CD) or ulcerative colitis (UC), who were followed as outpatients or during a hospitalization, participated, after informed consent was obtained from their legal representative. QOL was assessed by the IMPACT-III questionnaire. Demographic data and disease characteristics were also collected. Statistical analyses included parametric(Student's t-test and Pearson's r) and non-parametric(Mann-Whitney test, Fisher's test and Spearman's rho) procedures.RESULTS Ninety-nine patients (UC: 37, 73.0% females, CD: 62, 51.6% females), aged 12.8±2.6 years were included.Overall, as well as, sub-domain scores did not differ between UC and CD(overall score: 73.9±13.3 vs 77.5±11.2, respectively, P=0.16). In the entire sample, total score was related to physician's global assessment(PGA, patients classified as 'mild/moderate' active disease had, on average, 14.8±2.7 points lower total scores compared to those 'in remission', P<0.001) and age at IMPACT completion (Pearson's r=0.29, P=0.05). Disease activity assessed by the indices Pediatric Ulcerative Colitis activity index, Pediatric Crohn's disease activity index or PGA was significantly associated with all subdomains scores. Presence of extraintestinal manifestations had a negative impact on emotional and social functioning domains.CONCLUSION Disease activity is the main correlate of QOL in children with IBD, underlining the importance of achieving and sustaining clinical | Giorgos Chouliaras Daphne Margoni Konstantina Dimakou Smaragdi Fessatou Ioanna Panayiotou Eleftheria Roma-Giannikou | 2017 | World Journal of Gastroenterology2017，23，6： | 4 |
| 2 | Serum total homocysteine, folate, 5, 10-methylenetetrahydrofolate reductase (MTHFR) 677C→T genotype and subclinical atherosclerosis显示文摘 | Panayiotou A Nicolaides A Griffin M | 2009 | Expert Opin Ther Targets2009，13，1： | 1 |
| 3 | A sample path approach for solving the ground-holding policy problem in air traffic control显示文摘 | PANAYIOTOU C G CASSANDRAS C G | 2001 | IEEE Transactions on Control SystemsTechnology2001，9，3： | 1 |
| 4 | ApoB/ApoA 1 ratio and subclinical atherosclerosis 显示文摘 | Panayiotou A Griffin M Georgiou N | 2008 | Int Angiol2008，27，1： | 1 |
| 5 | Age-related differ- ences in simultaneous interarm blood pressure measurements 显示文摘 | Fotherby M D Panayiotou B Potter J F | 1993 | Postgrad Med J1993，69，809： | 1 |
| 6 | Effect of EAA and starch on the thermooxidative degradation of LDPE 显示文摘 | BIKIARIS D PRINOS J PANAYIOTOU C | 1997 | Polym Degrad Stab1997，56，1： | 1 |
| 7 | Dimensionality of Coping:An empirical contribution to the construct validation of the Brief - COPE with a Greek - speaking sample显示文摘 | Kapsou M Panayiotou G Kokkinos CM | 2010 | Journal of Health Psychology2010，15，2： | 1 |
| 8 | Perceived seri-ousness of pupils undesirable behavious:the student teachersperspective显示文摘 | Kokkinos C M Panayiotou G Davazoglou A M | 2004 | Educational Psychology2004，24，： | 1 |
| 9 | LDPE/starch blends compati-bilized with PE-^-MA copolymers显示文摘 | Bikiaris D Panayiotou C | 1998 | Journal of Ap-plied Polymer Science*1998，70，： | 1 |
| 10 | Thermal and colloidal behavior of amine-treated clays: The role of amphiphilic organic cation concentration显示文摘 | Marras SI Tsimpliaraki A Zuburtikudis I Panayiotou C | 2007 | Journal of Colloid and Interface Science2007，315，2： | 1 |
| 11 | Engineering reduced-immunogenicity enzymes for amino acid depletion therapy in cancer显示文摘 | Cantor J R Panayiotou V Agnello G | 2012 | Methods Enzymol2012，502，： | 1 |
| 12 | Nanostrueture vs microstructure: morphological and thermomechanical characterization of poly ( l-lactic acid )/layered silicate hybrids 显示文摘 | Sotirios I Marras loannis Zuburtikudis Costas Panayiotou | 2007 | European Polymer Journal2007，，： | 1 |
| 13 | Wind energy potential assessment in Naxos Island,Green显示文摘 | FYRIPPIS I AXAOPOULS P J PANAYIOTOU G | 2009 | Applied energy2009，87，2： | 1 |
| 14 | Foaming of chitin hydrogels processed by supercritical carbon dioxide显示文摘 | Tsioptsias C Panayiotou C | 2008 | J Supercrit Fluid2008，47，2： | 1 |
| 15 | Temperature effect on phenol extraction from water using mixed solvents 显示文摘 | GRAVELLED V PANAYIOTOU C | 1980 | Journal of Chemical & Engineering Data1980，25，1： | 1 |
| 16 | PLA2G7 genotype, lipoprotein-associated phospho- lipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls o{ European Ances- try显示文摘 | CASAS J P NINIO E PANAYIOTOU A | 2010 | Circulation2010，121，： | 1 |
| 17 | Effect of compatibilization on the performance of biodegradable composites using cotton fiber waste as filler显示文摘 | TSERKI V MATZINOS P PANAYIOTOU C | 2003 | Journal of Applied Polymer Science2003，88，： | 1 |
| 18 | PLA2G7genotype,lipoprotein-associated phospholipase A2activity,and coronary heart diseaserisk in 10494cases and 15624controls of European Ancestry显示文摘 | Casas JP Ninio E Panayiotou A | 2010 | Circulation2010，121，21： | 1 |
| 19 | Glass-fiber reinforcement of in situ compatibilized polypropylene/polyethylene blends 显示文摘 | TSELIO C BILIARIS D SAVIDIS P PANAYIOTOU C | 1999 | Journal of Materials Science1999，34，： | 1 |
| 20 | A study of the effect of acetylation and propionylation sur-face treatments on natural fibres 显示文摘 | Tserki V Zafeiropoulos N E Simon F Panayiotou C | 2005 | Composites Part A: Applied Science and Manufacturing2005，36，8： | 1 |
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