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| 1 | Predisposing factors for positive D-Xylose breath test for evaluation of small intestinal bacterial overgrowth:A retrospective study of 932 patients显示文摘AIM: To investigate, in the largest cohort to date, patient characteristics and associated risk factors for developing small intestinal bacterial overgrowth(SIBO) using the D-Xylose breath test(XBT).METHODS: We performed a retrospective crosssectional study to analyze patient characteristics who underwent the XBT for evaluation of SIBO. Diagnostic testing with the XBT was performed based on a clinical suspicion for SIBO in patients with symptoms of bloating, abdominal pain, abdominal distension, weight loss, diarrhea, and/or constipation. Consecutive electronicmedical records of 932 patients who completed the XBT at the University of Florida between 2005 and 2009 were reviewed. A two-way Analysis of Variance(ANOVA) was used to test for several associations including age, gender, and body mass index(BMI) with a +XBT. A two-way ANOVA was also performed to control for the differences and interaction with age and between genders. A similar analysis was repeated for BMI. Associations between medical conditions and prior surgical histories were conducted using the Mantel-Haenszel method for 2 by 2 contingency tables, stratified for gender. Reported odds ratio estimates reflect the odds of the prevalence of a condition within the +XBT group to that of the-XBT group. P values of less than 0.05(two-sided) were considered statistically significant.RESULTS: In the 932 consecutive eligible subjects studied, 513 had a positive XBT. A positive association was found between female gender and a positive XBT(P = 0.0025), and females with a positive test were, on average, greater than 5 years older than those with a negative test(P = 0.024). The mean BMI of positive XBT subjects was normal(24.5) and significantly lower than the subjects with a negative XBT(29.5)(P = 0.0050). A positive XBT was associated with gastroesophageal reflux disease(GERD)(OR = 1.35; 95%CI: 1.02-1.80, P = 0.04), peptic ulcer disease(PUD)(OR = 2.61; 95%CI: 1.48-4.59, P < 0.01), gastroparesis(GP)(OR = 2.04; 95%CI: 1.21-3.41, P < 0.01) and steroid use(OR = 1.35; 95%CI: 1.02-1.80, P = 0.01). Irritable bowel syndrome, independent protonpump inhibitor(PPI) usage, or previous abdominal surgery was not significantly associated with a positive XBT. No single subdivision by gender or PPI use was associated with a significant difference in the odds ratios between any of the subsets. CONCLUSION: Female gender, lower BMI, steroid use, PUD, GERD(independent of PPI use), and GP were more prevalent in patients with SIBO, determined by a positive XBT. Increasing age was associated with SIBO in females, but not in males. | Richard A Schatz Qing Zhang Nilesh Lodhia Jonathan Shuster Phillip P Toskes Baharak Moshiree | 2015 | World Journal of Gastroenterology2015，21，15： | 4 |
| 2 | Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya显示文摘 | Wendy P O'Meara Phillip Bejon Tabitha W Mwangi Emelda A Okiro Norbert Peshu Robert W Snow Charles RJC Newton Kevin Marsh | 2008 | The Lancet2008，，9649： | 2 |
| 3 | The FERET evaluation methodology for face-recognition algorithms显示文摘 | PHILLIPS P J MOON H RIZVI S A | 2000 | IEEE Transactions on PAM12000，22，10： | 1 |
| 4 | Rheological and physical differences between foam and emulsion fracturing fluids显示文摘 | Blauer R E Phillips A M Craig D P | 1988 | SPE18214 MS1988，，： | 1 |
| 5 | In vitro absorption of amino acids by the smallintestine of sheep显示文摘 | Phillips W A Webb K E Fontenot J P | 1976 | Journal of Animal Science1976，42，： | 1 |
| 6 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 7 | The role of potassium in muscle phosphorylations 显示文摘 | BOYER P D LARDY H A PHILLIPS P H | 1942 | Joumal of Biological Chemistry1942，146，： | 1 |
| 8 | Molecular basis for familial isolated growth hormone deficiency显示文摘 | PHILLIPS J A 3rd HJELLE B L SEEBURG P H | 1981 | Proc Natl Acad Sci U S A1981，78，： | 1 |
| 9 | The FERET evalua- tion methodology for face-recognition algorithms显示文摘 | Phillips P J Moon H Syed A | 2000 | IEEE Trans on Pattern Analysis and Machine InteUi- gence2000，22，10： | 1 |
| 10 | Using the theory of planned behaviour to investigate the determinants of recycling behaviour:a case study from Brixworth,UK显示文摘 | Tonglet M Phillips P S Read A D | | 0，，41： | 1 |
| 11 | FRVT 2006 and ICE 2006 large-scale ex- perimental results显示文摘 | Phillips P J Scruggs T O'Toole A Flynn P J Bowyer K W Sehott C Sharpe M | 2010 | IEEE Transactions on Pattern Analysis and Machine Intelligence2010，32，5： | 1 |
| 12 | Further studies on the role of potassium and other ions in the phospborylation of the adenylic system 显示文摘 | BOYER P D LARDY H A PHILLIPS P H | 1943 | Journal of Biological Chemistry1943，149，： | 1 |
| 13 | Radon mitigation in domestic properties and its health implications--a comparison between during-construction and post-construction radon reduction显示文摘 | Groves-Kirkby C J Denman A R Phillips P S | 2006 | Environ Int2006，32，4： | 1 |
| 14 | The FERET evaluation methodology for face-recognition algorithms显示文摘 | PHILLIPS P J MOON H RIZVI S A | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000，22，10： | 1 |
| 15 | Gibberellin metabolism: new in- sights revealed by the genes显示文摘 | Hedden P Phillips A L | 2000 | Trends Plant Sci2000，5，： | 1 |
| 16 | Does Decarboxyla- tion Lead to Cross--Linking in Low-Rank Coals 显示文摘 | Thorns P E Phillip F B Buchanan A C | 1996 | Energy Fuels1996，10，6： | 1 |
| 17 | A meta-analysis of the route of administration of luteal phase support in assisted reproductive technology:vaginal versus intramuscular progesterone显示文摘 | Zarutskie P W Phillips J A | 2009 | Fertil Steril2009，92，1： | 1 |
| 18 | The feret evaluation methodology for face-recognition algorithms 显示文摘 | P Jonathon Phillips Hyeonjoon Moon Syed A Rizvi Patrick J Rauss | 2000 | Pattern Analysis and Machine Intelligence IEEE Transactions on2000，22，10： | 1 |
| 19 | Effect of test position on pelvic floor muscle assessment显示文摘 | Frawley H C Galea M P Phillips B A | 2006 | Int Urogynecol J Pelvic Floor Dysfunct2006，17，4： | 1 |
| 20 | Face recognition: a literature survey 显示文摘 | Zhao W Chellappa R Rosenfeld A Phillips P J | 2003 | ACM Computing Surveys2003，35，4： | 1 |
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