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| 1 | Fermented soybean meal improves the growth performance, nutrient digestibility, and microbial flora in piglets显示文摘In order to increase nutritive values of soybean meal(SBM), 3 species of microbes were used to ferment SBM. Through a 3 x 3 orthogonal design and parameter measurements of soybean peptide and antinutritional factor contents in the fermented soybean meal(FSBM), it was estimated that the best microbial proportion of Bacillus subtilis, Hansenula anomala and Lactobacillus casei was 2:1:2 for SBM fermentation(P < 0.05). The further piglet feeding experiment showed that 10% FSBM substitute for SBM had no significant effect on growth performance of suckling piglets(d 7-28)(P> 0.05). However, newlyweaned piglets(d 28-38) fed 10% FSBM and different levels of plasma protein obtained higher average daily gain(ADG) and feed conversion ratio(FCR), compared with those without FSBM but with 6% plasma protein(P < 0.05). Piglets(d 38-68) fed diets supplemented with FSBM and soybean protein concentrate(SBPC) at 3.75% and 7.5% respectively increased nutrient digestibility,fecal enzyme activity and lactic acid bacteria counts, and decreased fecal Escherichia coli counts(P < 0.05), compared with the control. These data indicated that FSBM had positive effects on nutrient digestibility and fecal microflora for piglets. | Lin Yuan Juan Chang Qingqiang Yin Min Lu Yuanran Di Ping Wang Zhixiang Wang Erzhu Wang Fushan Lu | 2017 | Animal Nutrition2017，，1： | 31 |
| 2 | Structure evolution of oxygen removal from porous carbon for optimizing supercapacitor performance显示文摘The presence of oxygen functional groups is detrimental to the capacitive performance of porous carbon electrode in organic electrolyte. In this regards, hydrogen thermal reduction has been demonstrated effective approach in removing the unstable surface oxygen while maintaining the high porosity of carbon matrix. However, the exact evolution mechanism of various oxygen species during this process, as well as the correlation with electrochemical properties, is still under development. Herein, biomass-based porous carbon is adopted as the model material to trace its structure evolution of oxygen removal under hydrogen thermal reduction process with the temperature range of 400–800 °C. The optimum microstructure with low oxygen content of 0.90% and proper pore size distribution was achieved at 700°C. XPS, TPRMS and Boehm titration results indicate that the oxygen elimination undergoes three distinctive stages(intermolecular dehydration, hydrogenation and decomposition reactions). The optimum microstructure with low oxygen content of 0.90% and proper pore size distribution was achieved at 700 °C. Benefiting from the stable electrochemical interface and the optimized porous structure, the as-obtained HAC-700 exhibit significantly suppressed self-discharge and leak current, with improved cycling stability, which is attributable to the stabilization of electrochemical interface between carbon surface and electrolyte. The result provides insights for rational design of surface chemistry for high-performance carbon electrode towards advanced energy storage. | Siting Yuan Xianhong Huang Hao Wang Lijing Xie Jiayao Cheng Qingqiang Kong Guohua Sun Cheng-Meng Chen | 2020 | Journal of Energy Chemistry2020，29，12： | 16 |
| 3 | Effects of Deep Fluids on Hydrocarbon Generation and Accumulation in Chinese Petroliferous Basins显示文摘Deep fluids in a petroliferous basin generally come from the deep crust or mantle beneath the basin basement, and they transport deep substances(gases and aqueous solutions) as well as heat to sedimentary strata through deep faults. These deep fluids not only lead to large-scale accumulations of CO_2, CH_4, H_2, He and other gases, but also significantly impact hydrocarbon generation and accumulation through organic-inorganic interactions. With the development of deep faults and magmatic-volcanic activities in different periods, most Chinese petroliferous basins have experienced strong impacts associated with deep fluid activity. In the Songliao, Bohai Bay, Northern Jiangsu, Sanshui, Yinggehai and Pearl Mouth Basins in China, a series of CO_2 reservoirs have been discovered. The CO_2 content is up to 99%, with δ^(13)C_(CO2) values ranging from-4.1‰ to-0.37‰ and ~3He/~4He ratios of up to 5.5 Ra. The abiogenic hydrocarbon gas reservoirs with commercial reserves, such as the Changde, Wanjinta, Zhaozhou, and Chaoyanggou reservoirs, are mainly distributed in the Xujiaweizi faulted depression of the Songliao Basin. The δ^(13)CCH4 values of the abiogenic alkane gases are generally >-30‰ and exhibit an inverse carbon isotope sequence of δ^(13)C_(CH4)>δ^(13)C_(C2H6)>δ^(13)C_(C3H8)>δ^(13)C_(C4H10). According to laboratory experiments, introducing external H_2 can improve the rate of hydrocarbon generation by up to 147% through the kerogen hydrogenation process. During the migration from deep to shallow depth, CO_2 can significantly alter reservoir rocks. In clastic reservoirs, feldspar is easily altered by CO_2-rich fluids, leading to the formation of dawsonite, a typical mineral in high CO_2 partial pressure environments, as well as the creation of secondary porosity. In carbonate reservoirs, CO_2-rich fluids predominately cause dissolution or precipitation of carbonate minerals. The minerals, e.g., calcite and dolomite, show some typical features, such as higher homogenization temperatures than the burial temperature, relatively high concentrations of Fe and Mn, positive Eu anomalies, depletion of 18 O and enrichment of radiogenic ^(87)Sr. Due to CO_2-rich fluids, the development of high-quality carbonate reservoirs is extended to deep strata. For example, the Well TS1 in the northern Tarim Basin revealed a high-quality Cambrian dolomite reservoir with a porosity of 9.1% at 8408 m, and the Well ZS1 C in the central Tarim Basin revealed a large petroleum reserve in a Cambrian dolomite reservoir at ~6900 m. During the upward migration from deep to shallow basin strata, large volumes of supercritical CO_2 may extract petroleum components from hydrocarbon source rocks or deep reservoirs and facilitate their migration to shallow reservoirs, where the petroleum accumulates with the CO_2. Many reservoirs containing both supercritical CO_2 and petroleum have been discovered in the Songliao, Bohaiwan, Northern Jiangsu, Pearl River Mouth and Yinggehai Basins. The components of the petroleum trapped with CO_2 are dominated by low molecular weight saturated hydrocarbons. | ZHU Dongya LIU Quanyou JIN Zhijun MENG Qingqiang HU Wenxuan | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 12 |
| 4 | Clinical and CT imaging features of mucinous tubular and spindle cell carcinoma显示文摘 | Zhu Qingqiang Zhu Wenrong Wang Zhongqiu Wu Jingtao | 2014 | Chinese Medical Journal2014，，7： | 10 |
| 5 | Geochemical Characteristics and Genetic Types of Natural Gas in the Xinchang Gas Field, Sichuan Basin, SW China显示文摘The molecular compositions and stable carbon and hydrogen isotopic compositions of natural gas from the Xinchang gas field in the Sichuan Basin were investigated to determine the genetic types. The natural gas is mainly composed of methane (88.99%–98.01%), and the dryness coefficient varies between 0.908 and 0.997. The gas generally displays positive alkane carbon and hydrogen isotopic series. The geochemical characteristics and gas-source correlation indicate that the gases stored in the 5^(th) member of the Upper Triassic Xujiahe Formation are coal-type gases which are derived from source rocks in the stratum itself. The gases reservoired in the 4^(th) member of the Xujiahe Formation and Jurassic strata in the Xinchang gas field are also coal-type gases that are derived from source rocks in the 3^(rd) and 4^(th) members of the Xujiahe Formation. The gases reservoired in the 2^(nd) member of the Upper Triassic Xujiahe Formation are mainly coal-type gases with small amounts of oil-type gas that is derived from source rocks in the stratum itself. This is accompanied by a small amount of contribution brought by source rocks in the Upper Triassic Ma'antang and Xiaotangzi formations. The gases reservoired in the 4^(th) member of the Middle Triassic Leikoupo Formation are oil-type gases and are believed to be derived from the secondary cracking of oil which is most likely to be generated from the Upper Permian source rocks. | WU Xiaoqi LIU Quanyou LIU Guangxiang WANG Ping LI Huaji MENG Qingqiang CHEN Yingbin ZENG Huasheng | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 9 |
| 6 | The scientific connotation of oil and gas formations under deep fluids and organic-inorganic interaction显示文摘As a relatively stable craton block in the earth system, the petroliferous basin is influenced by the evolution of the earth system from the early development environment of source rocks, hydrocarbon formation, and reservoir dissolution to hydrocarbon accumulation or destruction. As a link between the internal and external factors of the basin, deep fluids run through the whole process of hydrocarbon formation and accumulation through organic-inorganic interaction. The nutrients carried by deep fluids promote the bloom of hydrocarbon-generating organisms and extra addition of carbon and hydrogen source, which are beneficial to the development of high-quality source rock and enhancement of the hydrocarbon generation potential. The energy carried by the deep fluid promotes the early maturation of the source rock and facilitates the hydrocarbon generation by activation and hydrogenation in high-mature hydrocarbon sources. The dissolution alteration of carbonate rocks and clastic reservoirs by CO_2-rich deep fluids improves the deep reservoir space, thus extending the oil and gas reservoir space into greater depth. The extraction of deeply retained crude oil by deep supercritical CO_2 and the displacement of CH_4 in shale have both improved the hydrocarbon fluidity in deep and tight reservoirs. Simultaneously, the energy and material carried by deep fluids(C, H, and catalytic substances) not only induce inorganic CH_4 formation by Fischer-Tropsch(F-T) synthesis and 'hydrothermal petroleum' generation from organic matter by thermal activity but also cause the hydrothermal alteration of crude oil from organic sources. Therefore, from the perspective of the interaction of the earth's sphere, deep fluids not only input a significant amount of exogenous C and H into sedimentary basins but also improve the reservoir space for oil and gas, as well as their enrichment and accumulation efficiencies. | Quanyou LIU Dongya ZHU Qingqiang MENG Jiayi LIU Xiaoqi WU Bing ZHOU Qi FU Zhijun JIN | 2019 | Science China Earth Sciences2019，62，3： | 8 |
| 7 | Trends of soil organic matter turnover in the salt marsh of the Yangtze River estuary显示文摘特征和土壤的潮汐的扁平的趋势有机物( SOM )周转在长江河口为 Chongmingdongtan 盐沼被学习基于稳定的碳同位素作文( 未1 3C )的分析,谷物微粒缩放并且满足器官的碳(停靠港),全部的氮( TN )和为从高潮汐的扁平的、中间的潮汐的公寓和赤裸的公寓挖掘的三个核心的无机的碳( TIC )。结果证明在土壤停靠港内容和盐沼核心的未 1 3C 价值之间的关联类似于在器官的碳(SOC ) 内容和未 1 3C 与不同高度多山的土壤侧面的上面的土壤层珍视的土壤之间的那些。盐沼的 SOM 通常比 100 年年轻,并且在长江的集水主要从表层土侵蚀发源。有 C/N 比率,满意于 TIC 内容的停靠港和停靠港的 TN 内容的关联与未 1 3C 价值满足因为核心建议从盐沼的 SOM 的周转度是全面的低,并且 SOM 周转的趋势从赤裸的公寓是清楚的到高潮汐的公寓。暴露原来的沉积的扁平的样品表演特征,与次要的 SOM 周转。SOM 的周转过程发生了并且在高、中间的潮汐的公寓,和有有泥泞潮汐的公寓的进化的不同周转率增加的 SOM 分隔空间的混合的度是可辨别的。交替的泥泞薄片和淤泥的薄片的独占的阶层结构在泥泞潮汐的公寓上从动态 depositional 过程发源是到溶解材料,和 SOM 周转的垂直移植的一个大障碍然后被抑制。泥泞潮汐的扁平的过程在盐沼对 SOM 的隐遁和周转施加了直接影响,并且在长江河口在 Chongmingdongtan 盐沼的 SOM 周转的空间、时间的特征上有大限制。 | CHEN Qingqiang GU Hequan ZHOU Juzhen MENG Yi HU Kelin | 2007 | Journal of Geographical Sciences2007，17，1： | 6 |
| 8 | Distribution and Geochemical Characteristics of Hydrogen in Natural Gas from the Jiyang Depression, Eastern China显示文摘Hydrogen gas accelerates hydrocarbon generation, but little is known about its distribution and origin in petroliferous basins, which has hindered the further exploration.Taken the Jiyang Depression in eastern China as an example, this study collected natural gas from different tectonic units, and analyzed various geochemical characters including gas contents, and carbon and hydrogen isotopic composition.The result shows that:(1) hydrogen gas is widespread distributed, but its content is very low, which typically ranges from 0.01% to 0.1% in this region;(2) the ratios of H2/3He, indicative of the origins of hydrogen gas, suggest that mantle-derived hydrogen is dominant.Even in tectonically stable areas absent with deep fluid activities, there is also mantle-derived;(3) the isotopic composition of hydrogen falls in the range of –798‰ to –628‰(relative to VSMOW standard).In areas with deep-derived fluids, the hydrogen gas has a similar isotopic composition with the previously documented deep-sourced gas, with lighter isotopic composition.In contrast, hydrogen gas has a heavier isotopic composition in relatively stable areas.The isotopic signatures suggest that there is a mixture of mantle- and crust-derived hydrogen gas in the relatively stable area, which is consistent with the H2/3He ratios.Therefore, it is clear that the hydrogen gas has a much wider distribution than found in the deep-derived fluid area, resulting in a much broader area with hydrogenating effect for resource rock.This understanding will provide new insights for hydrocarbon generation research and resource assessment in petroliferous basins. | MENG Qingqiang SUN Yuhua TONG Jianyu FU Qi ZHU Jun ZHU Dongya JIN Zhijun | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 5 |
| 9 | An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration显示文摘Endogenous repair of osteochondral defect is usually limited by the insufficient number of cells in the early stage and incomplete cell differentiation in the later stage.The development of drug delivery systems for sequential release of pro-migratory and pro-chondrogenic molecules to induce endogenous bone marrow-derived mesenchymal stem cells(BMSCs)recruitment and chondrogenic differentiation is highly desirable for in situ osteochondral regeneration.In this study,a novel,all-silk-derived sequential delivery system was fabricated by incorporating the tunable drug-loaded silk fibroin(SF)nanospheres into a SF porous matrix.The loading efficiency and release kinetics of biomolecules depended on the initial SF/polyvinyl alcohol(PVA)concentrations(0.2%,1%and 5%)of the nanospheres,as well as the hydrophobicity of the loaded molecules,resulting in controllable and programmed delivery profiles.Our findings indicated that the 5%nanosphere-incorporated matrix showed a rapid release of E7 peptide during the first 120 h,whereas the 0.2%nanosphere-incorporated matrix provided a slow and sustained release of Kartogenin(KGN)longer than 30 days.During in vitro culture of BMSCs,this functional SF matrix incorporated with E7/KGN nanospheres showed good biocompatibility,as well as enhanced BMSCs migration and chondrogenic differentiation through the release of E7 and KGN.Furthermore,when implanted into rabbit osteochondral defect,the SF nanosphere matrix with sequential E7/KGN release promoted the regeneration of both cartilage and subchondral bone.This work not only provided a novel all-silk-derived drug delivery system for sequential release of molecules,but also a functional tissueengineered scaffold for osteochondral regeneration. | Wei Zhang Chen Ling Aini Zhang Haoyang Liu Yujie Jiang ,Xiaolong Li Renwang Sheng Qingqiang Yao Jialin Chen | 2020 | Bioactive Materials2020，5，4： | 5 |
| 10 | Dissolution-filling mechanism of atmospheric precipitation controlled by both thermodynamics and kinetics显示文摘Affected by structural uplift,the Ordovician carbonate rockbed in the Tarim Basin,China,was exposed to dissolution and reformation of atmospheric precipitation many times,and formed a large quantity of karst caves serving as hydrocarbon reservoir.However,drilling in Tahe area showed that many large karst caves,small pores and fractures are filled by calcite,resulting in decrease in their reservoir ability.Calcite filled in the karst caves has very light oxygen isotopic composition and87Sr/86Sr ratio.Its 18OPDB ranges from 21.2‰to 13.3‰with the average of 16.3‰and its87Sr/86Sr ratio ranges from0.709561 to 0.710070 with the average of 0.709843.The isotope composition showed that calcite is related to atmospheric precipitation.Theoretic analyses indicated that the dissolving and filling actions of the precipitation on carbonate rocks are controlled by both thermodynamic and kinetic mechanisms.Among them,the thermodynamic factor determines that the precipitation during its flow from the earth surface downward plays important roles on carbonate rocks from dissolution to saturation,further sedimentation,and finally filling.In other words,the depth of the karstification development is not unrestricted,but limited by the precipitation beneath the earth surface.On the other hand,the kinetic factor controls the intensity,depth,and breadth of the karstification development,that is,the karstification is also affected by topographic,geomorphologic,climatic factors,the degree of fracture or fault,etc.Therefore,subject to their joint effects,the karstification of the precipitation on the Ordovician carbonate rocks occurs only within a certain depth(most about 200 m)under the unconformity surface,deeper than which carbonate minerals begin to sedimentate and fill the karst caves that were formed previously. | MENG QingQiang ZHU DongYa HU WenXuan JIN ZhiJun | 2013 | Science China Earth Sciences2013，56，12： | 4 |
| 11 | 发酵豆粕改善仔猪生长性能、营养物质消化率和肠道微生物菌群显示文摘为了提高豆粕的营养价值(SBM),选用3种微生物对豆粕进行发酵处理。采用3×3正交实验设计,通过对发酵豆粕(FSBM)中肽和抗营养因子含量进行测量分析,推测出豆粕发酵中枯草芽孢杆菌、汉逊酵母和干酪乳杆菌等微生物用量最佳比例2︰1︰2(P<0.05)。进一步动物实验表明,在哺乳期(7-28d),采用10%发酵豆粕替代豆粕对仔猪生长性能没有明显的影响(P>0.05)。然而,与没有添加发酵豆粕和添加6%血浆蛋白粉组相比,在断奶仔猪日粮中添加10%发酵豆粕和不同水平的血浆蛋白粉(0,2%,4%和6%)组断奶仔猪(d28-38)均可获得更高的日增重和饲料转化率(P<0.05)。此外,分别采用不同水平的发酵豆粕(3.75%和7.5%)和大豆浓缩蛋白(SBPC)(3.75%和7.5%)替代38-68日龄仔猪日粮中豆粕,与对照组相比,发酵豆粕和大豆浓缩蛋白组均可提高营养物质消化率、粪便中淀粉酶活性以及乳酸菌的数量,并降低粪便中大肠杆菌数量(P<0.05)。以上实验结果表明,发酵豆粕对仔猪营养物质消化率和肠道菌群有正调控作用。 | 王志林 Lin Yuan Juan Chang Qingqiang Yin Min Lu | 2017 | 广东饲料2017，26，1： | 4 |
| 12 | Influence of co-solvent hydroxyl group number on properties of water-based conductive carbon pastes显示文摘 | Chengjie Hua Xiaoming Li Lijuan Shen Hong Lei Xiaoqian Guo Zhuo Liu Qingqiang Kong Lijing Xie cheng-Meng Chen | 2017 | Particuology2017，15，4： | 3 |
| 13 | Effect of steam explosion and microbial fermentation on cellulose and lignin degradation of corn stover显示文摘 | Juan Chang Wei Cheng Qingqiang Yin Ruiyu Zuo Andong Song Qiuhong Zheng Ping Wang Xiao Wang Junxi Liu | 2011 | Bioresource Technology2011，，： | 3 |
| 14 | The effects of a new shape-memory alloy interspinous process device on the distribution of intervertebral disc pressures in vitro显示文摘This study was designed to measure the pressure distribution of the intervertebral disc under different degrees of distraction of the interspinous process, because of a suspicion that the degree of distraction of the spinous process may have a close relationship with the disc load share. Six human cadaver lumbar spine L2-L5 segments were loaded in flexion, neutral position, and extension. The L3-L4 disc load was measured at each position using pressure measuring films. Shape-memory interspinous process implants (SMID) with different spacer heights, ranging in size from 10 to 20 mm at 2 mm increments, were used. It was found that a SMID with a spacer height equal to the distance of the interspinous process in the neutral position can share the biomechanical disc load without a significant change of load in the anterior annulus. An interspinous process stabilizing device (IPD) would not be appropriate to use in those cases with serious spinal stenosis because the over-distraction of the interspinous process by the SMID would lead to overloading the anterior annulus which is a recognized cause of disc degeneration. | Shengnai Zheng Qingqiang Yao Li Cheng Yan Xu Peng Yuan Dongsheng Zhang Xiangwen Liao Liming Wang | 2010 | The Journal of Biomedical Research2010，24，2： | 2 |
| 15 | A Study on the Ore-forming Effect of Mantle-derived Fluid显示文摘Based on summarizing of the effect of mantle-derived fluid on the formation of ores,especially on gold ore,and with the latest investigations,such as the formation of ore from the action of shallow-deep fluid,the transportation effect of the thermal energy by mantle-derived fluid,this paper mainly aims at the effect of mantle-derived fluid on the generation of hydrocarbons. With the proof from geochemistry and fluid inclusion,it was suggested that the mantle-derived fluid not only supplied source materials for hydrocarbons,but also supplied essential energy and matter necessary for the generation of hydrocarbons. The mantle-derived fluid had a good effect,but at the same time it had an adverse effect under specific conditions,on the formation of reservoirs. This paper also discusses the future direction and significance of studying mantle-derived fluid. | Meng Qingqiang Wu Jianfeng Zhang Liuping | 2007 | Petroleum Science2007，4，4： | 2 |
| 16 | Significance of gypsum-salt rock series for marine hydrocarbon accumulation显示文摘With further exploration and research,the gypsum-salts rock series as good caprocks attracted a lot of attention.The gypsum-salt rock series played an important role during migration,preservation and trapping of hydrocarbons.Recently,major breakthroughs have been continuously made in marine petroleum exploration of gypsum-salt rock series in the eastern Ordos Basin,the central Tarim Basin and the western Sichuan Basin in China,and the high-evolution and low-abundance gypsum-salt rock series as hydrocarbon source rocks become possible.Besides research advances in the reservoirecaprock assemblage of gypsum-salt rock series,development and hydrocarbon-generation potential of source rocks in the gypsum-salt rock series were well studied in terms of source-rock development environment and hydrocarbon generation mechanism.Results showed that the gypsum-salt rock series,including high-evolution and low-TOC gypsum-salt rock series in China,could be regarded as good source rocks.This understanding was a breakthrough to previous traditional viewpoint that low-TOC gypsum-salt rock series could not act as effective hydrocarbon sources.The key to understand hydrocarbon-generation mechanism was that abundant and high-quality hydrocarbon-generation materials,large amount of hydrocarbon generation and conversion in geological history,and hydrocarbongeneration materials occurred in the form of carboxylates,were developed in the high-evolution and low-TOC gypsum-salt rock series. | Wenhui Liu Heng Zhao Quanyou Liu Bing Zhou Dianwei Zhang Jie Wang Longfei Lu Houyong Luo Qingqiang Meng Xiaoqi Wu | 2017 | Petroleum Research2017，2，3： | 2 |
| 17 | The first extra-large helium-rich gas field identified in a tight sandstone of the Dongsheng Gas Field,Ordos Basin,China显示文摘Helium gas is a scarce but important strategic resource,which is usually associated with natural gas.Presently,only one extra-large helium-rich gas field has been found in China:the Hetianhe Gas Field in the Tarim Basin.This paper reports a new example,the Dongsheng Gas Field(DGF)in the Ordos Basin.In this study,92 natural gas samples from the DGF were analyzed for helium content and isotope composition using isotope mass spectrometry.The natural gas samples were found to have an average helium content of 0.133%,with 65(70.7%)of the samples having a helium content of 0.1%or more.Based on the proven natural gas reserves of the DGF,the proven geological helium reserves were calculated to be 1.96×10^(8)m^(3),suggesting that it represents the first extra-large helium-rich natural gas reservoir to be hosted in tight sandstone in China.The ^(3)He/^(4)He ratios of 5 natural gas samples from the DGF are within the range of 3.03×10^(−8)–3.44×10^(−8).Therefore,the helium in the gas field is thought to be of typical crustal origin and to have formed in the granitic basement that is rich in uranium and thorium.The accumulation of helium-rich natural gas was controlled by regional tectonic activities.Activity along the fault connecting the reservoir with the basement caused release of the helium gas,which entered the overlying strata along the fault and accumulated with conventional hydrocarbon gas.Based on the structural background and the distribution of helium source rocks in the Ordos Basin,the main helium source rocks with high exploration potential are located in deep strata within the north and middle parts of the basin. | Weilong PENG Quanyou LIU Ying ZHANG Huichong JIA Dongya ZHU Qingqiang MENG Xiaoqi WU Shang DENG Yongsheng MA | 2022 | Science China Earth Sciences2022，65，5： | 2 |
| 18 | Silk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration显示文摘Osteochondral defects(OCD)cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation.Conventional strategies,such as the control of implant microstructure or the introduction of growth factors,have limited functions failing to manage these complex environments.Here we developed a multifunctional silk-based hydrogel incorporated with metal-organic framework nanozymes(CuTA@SF)to provide a suitable microenvironment for enhanced OCD regeneration.The incorporation of CuTA nanozymes endowed the SF hydrogel with a uniform microstructure and elevated hydrophilicity.In vitro cultivation of mesenchymal stem cells(MSCs)and chondrocytes showed that CuTA@SF hydrogel accelerated cell proliferation and enhanced cell viability,as well as had antioxidant and antibacterial properties.Under the inflammatory environment with the stimulation of IL-1β,CuTA@SF hydrogel still possessed the potential to promote MSC osteogenesis and deposition of cartilage-specific extracellular matrix(ECM).The proteomics analysis further confirmed that CuTA@SF hydrogel promoted cell proliferation and ECM synthesis.In the full-thickness OCD model of rabbit,CuTA@SF hydrogel displayed successfully in situ OCD regeneration,as evidenced by micro-CT,histology(HE,S/O,and toluidine blue staining)and immunohistochemistry(Col I and aggrecan immunostaining).Therefore,CuTA@SF hydrogel is a promising biomaterial targeted at the regeneration of OCD. | Zhicheng Cao Hongmei Wang Jialin Chen Yanan Zhang Qingyun Mo Po Zhang Mingyue Wang Haoyang Liu Xueyang Bao Yuzhi Sun Wei Zhang Qingqiang Yao | 2023 | Bioactive Materials2023，，2： | 2 |
| 19 | Simultaneous measurement of curvature and temperature with fiber taper-based MZI containing fiber Bragg grating显示文摘 | Meng Qingqiang Dong Xinyong Zhou Yan | 2012 | Journal of Electromagnetic and Applications2012，26，1718： | 1 |
| 20 | A rare chronic constrictive pericarditis with localized adherent visceral pericardium and normal parietal pericardium: a case report显示文摘经典紧缩的心包炎(CP ) 被含纤维的结疤和内脏的心包和顶骨心包的粘附描绘,它导致限制心脏的充满。然而,与正常厚度心包并且没有石灰化诊断 CP 仍然是挑战。在发达世界上的占优势的原因是 cardiac 以后外科跟随的自发或病毒的心包炎并且放射以后。肺结核在开发国家仍然是 CP 的一个普通原因。在这份报告,我们在一个中年的人与顶骨心包的正常厚度描述自发的局部性的紧缩的内脏的心包的一个稀罕案例。与 unexplained 权利心失败和 echocardiography 介绍的病人看中等 bi-atrial 增大哪个应该与限制心肌症被识别。在 10 月保守治疗以后,正确的心失败的前进正在留下。pericardiectomy 被执行,病人恢复了。这个案例用作一个提示与 unexplained 权利心失败在病人考虑 CP,以便及时调查和治疗能被开始。 | Qingqiang Ni Lin Yun Rui Xu Guohua Li Yucai Yao Jiamin Li | 2016 | Frontiers of Medicine2016，10，3： | 1 |
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