|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Complications of hip fractures: A review显示文摘Nowadays, fracture surgery represents a big part of the orthopedic surgeon workload, and usually has associated major clinical and social cost implications. These fractures have several complications. Some of these are medical, and other related to the surgical treatment itself. Medical complications may affect around 20% of patients with hip fracture. Cognitive and neurological alterations, cardiopulmonary affections(alone or combined), venous thromboembolism, gastrointestinal tract bleeding, urinary tract complications, perioperative anemia, electrolytic and metabolic disorders, and pressure scars are the most important medical complications after hip surgery in terms of frequency, increase of length of stay and perioperative mortality. Complications arising from hip fracture surgery are fairly common, and vary depending on whether the fracture is intracapsular or extracapsular. The main problems in intracapsular fractures are biological: vascularization of the femoral head, and lack of periosteum-a major contributor to fracture healing- in the femoral neck. In extracapsularfractures, by contrast, the problem is mechanical, and relates to load-bearing. Early surgical fixation, the role of anti-thromboembolic and anti-infective prophylaxis, good pain control at the perioperative, detection and management of delirium, correct urinary tract management, avoidance of malnutrition, vitamin D supplementation, osteoporosis treatment and advancement of early mobilization to improve functional recovery and falls prevention are basic recommendations for an optimal maintenance of hip fractured patients. | Pedro Carpintero Jose Ramón Caeiro Rocío Carpintero Angela Morales Samuel Silva Manuel Mesa | 2014 | World Journal of Orthopedics2014，5，4： | 31 |
| 2 | Platelet count/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis显示文摘AIM:To validate whether the platelet count/spleen size ratio can be used to predict the presence of esophageal varices in Mexican patients with hepatic cirrhosis.METHODS:This was an analytical cross-sectional study to validate the diagnostic test for hepatic cirrhosis and was performed between February 2010 and December 2011.Patients with a diagnosis of hepatic cirrhosis were included and stratified using their ChildPugh score.Biochemical parameters were evaluated,and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated and analyzed to determine whether it can predict the presence of esophageal varices.Upper gastrointestinal endoscopy was used as the gold standard.Sensitivity and specificity,positive and negative predictive values,and positive and negative likelihood ratios were determined,with the cutoff points determined by receiver-operating characteristic curves.RESULTS:A total of 91 patients were included.The mean age was 53.75±12 years;50(54.9%)were men,and 41(45.0%)women.The etiology of cirrhosis included alcohol in 48(52.7%),virally induced in24(26.3%),alcoholism plus hepatitis C virus in three(3.2%),cryptogenic in nine(9.8%),and primary biliary cirrhosis in seven(7.6%).Esophageal varices were present in 73(80.2%)patients.Child-Pugh classification,17(18.6%)patients were classified as class A,37(40.6%)as class B,and 37(40.6%)as class C.The platelet count/spleen diameter ratio to detect esophageal varices independent of the grade showed using a cutoff value of≤884.3,had 84%sensitivity,70%specificity,and positive and negative predictive values of 94%and 40%,respectively.CONCLUSION:Our results suggest that the platelet count/spleen diameter ratio may be a useful tool for detecting esophageal varices in patients with hepatic cirrhosis. | Alejandro González-Ojeda Gabino Cervantes-Guevara Manuela Chávez-Sánchez Carlos Dávalos-Cobián Susana Ornelas-Cázares Michel Dassaejv Macías-Amezcua Mariana Chávez-Tostado Kenia Militzi Ramírez-Campos Anaís del Rocío Ramírez-Arce Clotilde Fuentes-Orozco | 2014 | World Journal of Gastroenterology2014，20，8： | 18 |
| 3 | Timely reperfusion for ST-segment elevation myocardial infarction:Effect of direct transfer to primary angioplasty on time delays and clinical outcomes显示文摘Primary percutaneous coronary intervention(PPCI) is the preferred reperfusion therapy for patients presenting with ST-segment elevation myocardial infarction(STEMI) when it can be performed expeditiously and by experienced operators. In spite of excellent clinical results this technique is associated with longer delays than thrombolysis and this fact may nullify the benefit of selecting this therapeutic option. Several strategies have been proposed to decrease the temporal delays to deliver PPCI. Among them,prehospital diagnosis and direct transfer to the cath lab,by-passing the emergency department of hospitals,has emerged as anattractive way of diminishing delays. The purpose of this review is to address the effect of direct transfer on time delays and clinical events of patients with STEMI treated by PPCI. | Rodrigo Estévez-Loureiro ángela López-Sainz Armo Pérez de Prado Carlos Cuellas Ramón Calvio Santos Norberto Alonso-Orcajo Jorge Salgado Fernández Jose Manuel Vázquez-Rodríguez Maria López-Benito Felipe Fernández-Vázquez | 2014 | World Journal of Cardiology2014，6，6： | 6 |
| 4 | Epigenetic basis of Alzheimer disease显示文摘Alzheimer disease(AD)is the primary form of dementia that occurs spontaneously in older adults.Interestingly,the epigenetic profile of the cells forming the central nervous system changes during aging and may contribute to the progression of some neurodegenerative diseases such as AD.In this review,we present general insights into relevant epigenetic mechanisms and their relationship with aging and AD.The data suggest that some epigenetic changes during aging could be utilized as biomarkers and target molecules for the prevention and control of AD. | Angeles C Tecalco-Cruz JosuéO Ramírez-Jarquín María E Alvarez-Sánchez Jesus Zepeda-Cervantes | 2020 | World Journal of Biological Chemistry2020，11，2： | 4 |
| 5 | Clinical hematological and biochemical parameters in Swiss,BALB/c,C57BL/6 and B6D2F1 Mus musculus显示文摘Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific studies.Our study seeks to establish reference values for hematological and biochemical parameters of four lineages of mice.Methods:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages Swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 mice.Analysis were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical parameters.Results:Results are shown as means and standard deviation,grouped by lineage and genre.Comparing the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual variability.Conclusion:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model. | Giorgio Silva-Santana Juliet Cunha Bax Débora Cristina Silva Fernandes Daniela Tendler Leibel Bacellar Cleber Hooper Alexandre Alves Souza Oliveira Dias Cristina Barbosa Silva Aline Moreira de Souza Simone Ramos Ricardo Alexandre Santos Thainara Ramos Pinto Mariana Antunes Ramão Ana Luíza Mattos-Guaraldi | 2020 | Animal Models and Experimental Medicine2020，3，4： | 2 |
| 6 | Polyubiquitination inhibition of estrogen receptor alpha and its implications in breast cancer显示文摘Estrogen receptor alpha(ERα) is detected in more than 70% of the cases of breast cancer. Nuclear activity of ERα, a transcriptional regulator, is linked to the development of mammary tumors, whereas the extranuclear activity of ERα is related to endocrine therapy resistance. ERα polyubiquitination is induced by the estradiol hormone, and also by selective estrogen receptor degraders, resulting in ERα degradation via the ubiquitin proteasome system. Moreover, polyubiquitination is related to the ERα transcription cycle, and some E3-ubiquitin ligases also function as coactivators for ERα. Several studies have demonstrated that ERα polyubiquitination is inhibited by multiple mechanisms that include posttranslational modifica-tions, intera-ctions with coregula-tors, a-nd forma-tion of specific protein complexes with ERα. These events are responsible for an increase in ERα protein levels and deregulation of its signaling in breast cancers. Thus, ERα polyubiquitination inhibition may be a key factor in the progression of breast cancer and resistance to endocrine therapy. | Angeles C Tecalco-Cruz Josué O Ramírez-Jarquín | 2018 | World Journal of Clinical Oncology2018，9，4： | 2 |
| 7 | Developing seedless grapes by embryo rescue显示文摘 | Ramming DW Lu J Lamikanra O | 1995 | Proc-Vitis-SciSymp1995，18，： | 1 |
| 8 | A specific role for the thalamus in medicating the interaction of attention and arousal in humans显示文摘 | Portas CM Howseman RAM Josephs O | 1998 | Journal of NeuroScience1998，18，21： | 1 |
| 9 | Effect of boron addition on the activity and selectivity of hydrotreating CoMo/Al2O3 catalysts显示文摘 | RAM REZ J CASTILLO P CEDE O L | 1995 | Appl Catal: A1995，132，2： | 1 |
| 10 | Epstein - Barr virus and cytomegalovirus in autoimmune diseases:are they truly notorious? A preliminary report 显示文摘 | Barzilai O Sherer Y Ram M | 2007 | Ann N Y Acad Sci2007，1108，： | 1 |
| 11 | A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer显示文摘 | Covadonga Huidobro Rocío G. Urdinguio Ramón María Rodríguez Cristina Mangas Vincenzo Calvanese Pablo Martínez-Camblor Cecilia Ferrero Adolfo Parra-Blanco Luis Rodrigo álvaro J. Obaya Laura Suárez-Fernández Aurora Astudillo Henar Hernando Esteban Ballestar | 2011 | European Journal of Cancer2011，，14： | 1 |
| 12 | The acute and long-term effect of balloon sphincteroplasty on papillary structure in pigs显示文摘 | Padraic Mac Mathuna David Siegenberg David Gibbons Daniel Gorin Michael O’Brien Nezem A. Afdhal Ram Chuttani | 1996 | Gastrointestinal Endoscopy1996，，6： | 1 |
| 13 | High Amino Acid Variation in the Intracellular Domain of the Pig Prolactin Receptor (PRLR) and Its Relation to Ovulation Rate and Piglet Survival Traits显示文摘 | TOMS A CASELLAS J RAMEZ O | 2006 | J Anim Sci2006，84，： | 1 |
| 14 | Synthesis and characterization of Ce-stabilized titania for NiMo HDS catalysts显示文摘 | L. Cede?o R. Zanella J. Ramírez H. Mendoza G. Hernández P. Schacht | 2004 | Catalysis Today2004，，1： | 1 |
| 15 | Epstein - Barr virus and cyto- megalovirus in autoimmune diseases: are they truly notorious? A pre- liminary report显示文摘 | Barzilai O Sherer Y Ram M | 2007 | Ann NY Acad Sci2007，11，8： | 1 |
| 16 | Operational strategies,monitoring and control of heterologous protein production in the methylotrophic yeast pichia pastoris under different promoters显示文摘 | Cos O Ramón R Montesinos JL | 2006 | Microb Cell Fact2006，5，1： | 1 |
| 17 | Quantum confinement effects in CdTe nanostructured films prepared by the RF sputtering technique 显示文摘 | Arizpe-Cha'vez H Ram'rez-Bon R Zelaya-Angel O | 2000 | Journal of Physics and Chemistry of Solids2000，61，： | 1 |
| 18 | The contribution of plant food antioxidants to human health 显示文摘 | Ram arattmam N O saw a T Och i H | 1995 | 1 T rends in Food Science and Technology1995，6，： | 1 |
| 19 | A GIS-embedded system to support land consolidation plans in Galicia显示文摘 | Juan Touri(n)o Jorge Parapar Ramón Doallo | 2003 | International Journal of Geographical Information Science2003，17，4： | 1 |
| 20 | Ionizing radiation up-regulates telomerase activity in cancer cell lines by post-translationol mech- anism via ras/Phosphatidylino-sitol 3-kinase/akt pathway 显示文摘 | Ram R Uziel O Eldan O | 2009 | Clin Cancer Res2009，15，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员