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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Differential scanning calorimetry material studies:implications for the safety of lithium-ion cells显示文摘 | ZHANG Z FOUCHARD D REA J R | 1998 | J Power Sources1998，70，： | 1 |
| 3 | Differential scanning calor- imetry material studies: implications for the safety of lithium-ion cells显示文摘 | ZHANG Z FOUCHARD D REA J R | 1998 | Journal of Power Sources1998，700，： | 1 |
| 4 | Dissociation of oceanic methane hydrate as a cause of the carbon isotope ezcursion at the end of the Paleocene显示文摘 | Dickens G R O'Neil J R Rea D K | 1995 | Paleoceanography1995，10，： | 1 |
| 5 | Grain-size distribu-tion function of polymodal sediments in hydraulic and aeoli-an environments,and numerical partitioning of the sedimen-tary components显示文摘 | Sun D H Bloemendal J Rea D K | 2002 | Sedimentary Geology2002，152，34： | 1 |
| 6 | Late Pleistocene paleoclimatology of the central equatorial Pacific: a quantitative record of eolian and carbonate deposition显示文摘 | Chuey J M Rea D K Pisias N G | 1987 | Quatary Research1987，28，： | 1 |
| 7 | Adjuvant tamoxifen and ex- emcstane in early breast cancer (TEAM) : a randomised phase 3 trial 显示文摘 | Van De Velde C J Rea D Seynaeve C et at | 2011 | Lancet2011，377，9762： | 1 |
| 8 | Phase 2 study of subcutaneous omacetaxine mepesuccinate after TKI failure in patients with chronic-phase CML with T315I mutation显示文摘 | Cortes J Lipton JH Rea D | 2012 | Blood2012，120，13： | 1 |
| 9 | Grain-size distribution function of polymodal sediments in hydraulic and Aeolian environments, and numerical partitioning of the sedimentary components 显示文摘 | Sun D H Bloem E J Rea D K | 2002 | Sedimentary Geology2002，152，3： | 1 |
| 10 | Differential scanning calorimetry material studies: implications for the safety of lithium-ion cell显示文摘 | FOUCHARD D REA J R | 1998 | Journal of Power Sources1998，70，： | 1 |
| 11 | Bimodal grain-size distribution of Chinese loess and its palaeoclimatic implications 显示文摘 | Sun D H Bloem E J Rea D K | 2004 | Catena2004，55，3： | 1 |
| 12 | Grain-size distribution function of polymodal sediments in hydraulic and aeolian environments,and numerical partitioning of the sedimentary components显示文摘 | Sun D Bloemendal J Rea D K | 2002 | Sedimentary Geology2002，152，3： | 1 |
| 13 | Part 4:CPR overview:2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care显示文摘 | Travers A H Rea T D Bobrow B J | 2010 | Circulation2010，122，3： | 1 |
| 14 | Bimodal grain-sizedistribution of Chinese loess,and its palaeo climatic impli-cations显示文摘 | Sun D H Bloemendal J Rea D K | 2004 | Catena2004，55，3： | 1 |
| 15 | Dissociation of oceanic methane hydrate as a cause of the carbon isotope excursion at the end of the Paleocene显示文摘 | Dickens G R O'Neil J R Rea D K | 1995 | Paleoceanography1995，10，： | 1 |
| 16 | CPR overview:2010 American Heart Association Guidelines for CPR and ECC显示文摘 | Andrew H Travers Chomas D Rea Bentley J Bobrow | 2010 | Circulation2010，122，13： | 1 |
| 17 | Differential scanning calorimetry material studies:implications for the safety of lithium-ion cells显示文摘 | Zhang Z Fouchard D Rea J R | 1998 | J Power Sources1998，70，1： | 1 |
| 18 | Utilization of laparoscopic colectomy in the United States before and after the clinical outcomes of surgical therapy study group trial显示文摘 | REA J D CONE M M DIGGS B S | | 0，，02： | 1 |
| 19 | Bimodal grain- size distribution of Chinese loess, and its palaeoclimatic impli- cations显示文摘 | Sun Donghuai Bloemendal J Rea D K | 2004 | Catena2004，55，3： | 1 |
| 20 | Grain size dis- tribution function of polymodal sediments in hydraulic and Aeolian environments, and numerical partitioning of the sedi- mentary components 显示文摘 | Sun Donghuai Bloemendal J Rea D K | 2002 | Sedimentary Geology2002，152，34： | 1 |
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