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| 1 | Cytokine orchestration in post-operative peritoneal adhesion formation显示文摘Peritoneal adhesions are a near inevitable occurrence after laparotomy and a major cause of both patient and physician misery. To date, clinical attempts at their amelioration have concentrated on manipulating the physical factors that affect their development despite a wealth of experimental data elucidating the molecular mechanisms that underlie their initiation, development and maturation. However, the advent of targeted, specific anti-cytokine agents as directed therapy for inflammatory and neoplastic conditions raises the prospect of a new era for anti-adhesion strategies. To harness this potential will require considerable cross-disciplinary collaboration and that surgeon-scientists propel themselves to the forefront of this emerging fi eld. | Ronan A Cahill H Paul Redmond | 2008 | World Journal of Gastroenterology2008,14,31: | 6 |
| 2 | Current knowledge and future directions of TLR and NOD signaling in sepsis显示文摘The incidence of sepsis is increasing over time, along with an increased risk of dying from the condition. Sepsis care costs billions annually in the United States. Death from sepsis is understood to be a complex process, driven by a lack of normal immune homeostatic functions and excessive production of proinflammatory cytokines, which leads to multi-organ failure. The Toll-like receptor(TLR) family, one of whose members was initially discovered in Drosophila, performs an important role in the recognition of microbial pathogens. These pattern recognition receptors(PRRs), upon sensing invading microorganisms, activate intracellular signal transduction pathways. NOD signaling is also involved in the recognition of bacteria and acts synergistically with the TLR family in initiating an efficient immune response for the eradication of invading microbial pathogens. TLRs and NOD1/NOD2 respond to different pathogenassociated molecular patterns(PAMPs). Modulation of both TLR and NOD signaling is an area of research that has prompted much excitement and debate as a therapeutic strategy in the management of sepsis. Molecules targeting TLR and NOD signaling pathways exist but regrettably thus far none have proven efficacy from clinical trials. | Niamh M Foley Jian Wang H Paul Redmond Jiang-Huai Wang | 2014 | Journal of Medical Colleges of PLA(China)2014,29,4: | 2 |
| 3 | Molecular analysis of cellulose biosynthesis in Arabidopsis显示文摘 | ARIOLI T PENG L BETZNER A S BURN J WITTKE W HERTH W CAMILLERI C H(O)FTE H PLAZINSKI J BIRCH R CORKA GLOVER J REDMOND J WILLIAMSDN R E | 1998 | Science1998,279,: | 1 |
| 4 | Lung Injury in Acute Pancreatitis: Mechanisms, Prevention, and Therapy显示文摘 | Shields C J Winter D C Redmond H P | 2002 | Curr Opin Crit Care2002,8,2: | 1 |
| 5 | Cell response to surgery显示文摘 | Choileain N N Redmond H P | 2006 | Arch Surg2006,141,11: | 1 |
| 6 | Photoinduced hydrogen atom transfer in salicylic acid derivatives used as matrix-assisted laser desorption/ionization (Maldi) matrixes 显示文摘 | Ludemann H C Hillenkamp F Redmond R W | 2000 | Journal of Physical Chem- istry A2000,104,: | 1 |
| 7 | What does big data mean for wearable sensor systems? Contribution of the IMIA wearable sensors in healthcare WG 显示文摘 | REDMOND S J LOVELL N H YANG G Z | 2014 | Yearb Med Inform2014,9,1: | 1 |
| 8 | The DY sub -region of the sheep MHC contains an A/B gene pair显示文摘 | Wright H Ballingall K T Redmond J | 1994 | Immunogenetics1994,40,3: | 1 |
| 9 | A general approach to desalting oligosaccharides released from glycoproteins显示文摘 | Nicolle H Packer Margaret A Lawson Daniel R Jardine John W Redmond | 1998 | Glycoconjugate Journal1998,,8: | 1 |
| 10 | Immunomitrition:the role of taurine显示文摘 | Redmond H P Frcsi M Stapleton P P | 1998 | Nutrition1998,14,7: | 1 |
| 11 | Tau- rine and human nutrition显示文摘 | STAPLETON P P CHARLES R P REDMOND H P | 1997 | Clin Nutr1997,16,3: | 1 |
| 12 | The health care crisis in the United States:a call to action显示文摘 | Redmond H | | 0,,01: | 1 |
| 13 | Lowering of serum cholesterol by intestinal bacteria in cholesterol-fed piglets显示文摘 | Glen E Mott R Wayne Moore Redmond H E | 1973 | Shirt Communications1973,8,7: | 1 |
| 14 | Immunonutrition:the role of taurine显示文摘 | Redmond H P Stapleton P P Neary P | 1998 | Nutrition1998,14,78: | 1 |
| 15 | Bacterial lipoprotein-induced self-tol- erance and cross-tolerance to I2S are associated with reduced IRAK-I expression and MyD88-IRAK complex formation 显示文摘 | Li C H Wang J H Redmond H P | 2006 | J Leukoc Biol2006,79,4: | 1 |
| 16 | T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells显示文摘 | Redmond KL Crawford NT Farmer H | 2010 | Oncogene2010,29,22: | 1 |
| 17 | Characterization of O-linked glycosylation motifs in the glycopeptide domain of bovine kappa-casein显示文摘 | PISANO A PACKER N H REDMOND J W | 1994 | Glycobiology1994,4,6: | 1 |
| 18 | Cellres Ponseto Surgery显示文摘 | Choileain N N Redmond H P | 2006 | Arch Surg2006,141,11: | 1 |
| 19 | Lowering of serum cholesterol by intestinal bacteria in cholesterol-fed piglets 显示文摘 | MOTT G E MOORE R W REDMOND H E | 1973 | Lipids1973,8,7: | 1 |
| 20 | Immunonutrition: the role of taurine 显示文摘 | Redmond H P Stapleton P P Neary P | 1998 | Nutriology1998,14,: | 1 |