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| 1 | 群体比专家更明智?显示文摘所有高管都知道,做商业决策时所用的信息往往并不完整。但是,决策者却很少向那些直接与客户交流的低层员工请教,如向他们咨询如何有效推广新产品等问题。这样一来,领导者自己剥夺了自己获得有价值信息的机会,而这些信息不仅能让他们的分析更加透彻,还能降低决策中闭门造车的风险。 | Renée Dye | 2008 | 商学院2008,,10: | 1 |
| 2 | Oropharyngeal Dysphagia显示文摘 | Renée Speyer | 2013 | Otolaryngologic Clinics of North America2013,,6: | 1 |
| 3 | The Role of Collagen Triple Helix Repeat Containing 1 in Injured Arteries, Collagen Expression, and Transforming Growth Factor β Signaling显示文摘 | Renée LeClair Volkhard Lindner | 2007 | Trends in Cardiovascular Medicine2007,,6: | 1 |
| 4 | 长兄如父之美国版显示文摘1长兄如父,这句由四个平常汉字组成的话有着不同寻常的份量。这句中国祖训在大洋彼岸一个有七个弟妹的大哥身上同样得到了体现。布赖恩·威尔莫斯是家中八个兄弟姐妹中的老大。他们在严厉的宗教家庭中长大。多年来,所有的兄弟姐妹都渐渐与父母疏远了。布赖恩是个同性恋者,他是第一个被赶出家门的。他向弟弟迈克尔讲述当时的情形。布赖恩:父亲在我的杂物盒里发现了一封男生写的情书,他看完后便失去了理智。 | Renée Montagne BTW | 2015 | 疯狂英语(新悦读)2015,0,3: | 0 |
| 5 | Tumor necrosis factor-α inhibitor therapy and fetal risk:A systematic literature review显示文摘Tumor necrosis factor-α inhibitors (anti-TNFs) are effective in the treatment of inflammatory bowel disease (IBD) recalcitrant to conventional medical therapy. As the peak incidence of IBD overlaps with the prime reproductive years, it is crucial to establish pharmacologic regimens for women of childbearing age that achieve effective disease control without posing significant fetal harm. A systematic literature review was performed to identify all human studies with birth outcomes data after maternal exposure to infliximab, adalimumab, or certolizumab pegol within 3 mo of conception or during any trimester of pregnancy. Live births, spontaneous abortions or stillbirths, preterm or premature births, low birth weight or small for gestational age infants, and congenital abnormalities were recorded. Fifty selected references identified 472 pregnancy exposures. The subsequent review includes general information regarding anti-TNF therapy in pregnancy followed by a summary of our findings. The benefits of biologic modalities in optimizing disease control during pregnancy must be weighed against the potential toxicity of drug exposure on the developing fetus. Although promising overall, there is insufficient evidence to prove absolute safety for use of anti-TNFs during pregnancy given the limitations of available data and lack of controlled trials. | Renée M Marchioni Gary R Lichtenstein | 2013 | World Journal of Gastroenterology2013,19,17: | 11 |
| 6 | Women in the boardroom and their impact on governance and performance显示文摘 | Renée B. Adams Daniel Ferreira | 2009 | Journal of Financial Economics2009,,2: | 3 |
| 7 | Viral-mediated gene therapy for spinal cord injury(SCI) from a translational neuroanatomical perspective显示文摘Repairing spinal cord injury(SCI)is one of the most challenging endeavours currently faced by neuroscientists.One promising therapeutic avenue to reverse this once considered permanent condition is gene therapy,however progress has been hampered by the anatomica intricacy of the spinal cord itself as well as by the sheer complexity of the molecular cascades of events that take place in the injured cord. | Andrew P Tosolini Renée Morris | 2016 | Neural Regeneration Research2016,11,5: | 2 |
| 8 | WJH 6^(th) Anniversary Special Issues(2): Hepatocellular carcinoma Mammalian target of rapamycin inhibition in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is one of the leading causes of cancer-related death worldwide. It is associated with a poor prognosis and has limited treatment options. Sorafenib, a multi-targeted kinase inhibitor, is the only available systemic agent for treatment of HCC that improves overall survival for patients with advanced stage disease; unfortunately, an effective second-line agent for the treatment of progressive or sorafenib-resistant HCC has yet to be identified. This review focuses on components of the mammalian target of rapamycin(mTOR) pathway, its role in HCC pathogenesis, and dual mTOR inhibition as a therapeutic option with potential efficacy in advanced HCC. There are several important upstream and downstream signals in the mTOR pathway, and alternative tumor-promoting pathways are known to exist beyond mTORC1 inhibition in HCC. This review analyzes the relationships of the upstream and downstream regulators of mTORC1 and mTORC2 signaling; it also provides a comprehensive global picture of the interaction between mTORC1 and mTORC2 which demonstrates the pre-clinical relevance of the mTOR pathway in HCC pathogenesis and progression. Finally, it provides scientific rationale for dual mTORC1 and mTORC2 inhibition in the treatment of HCC. Clinical trials utilizing mTORC1 inhibitors and dual mTOR inhibitors in HCC are discussed as well. The mTOR pathway is comprised of two main components, mTORC1 and mTORC2; each has a unique role in the pathogenesis and progression of HCC. In phase Ⅲ studies, mTORC1 inhibitors demonstrate anti-tumor ac-tivity in advanced HCC, but dual mTOR(mTORC1 and mTORC2) inhibition has greater therapeutic potential in HCC treatment which warrants further clinical investigation. | René E Ashworth Jennifer Wu | 2014 | World Journal of Hepatology2014,6,11: | 2 |
| 9 | A survey of antifungal compounds from higher plants,1982-1993显示文摘 | Renée J Grayer Jeffrey B | 1994 | Phytochemistry1994,37,1: | 1 |
| 10 | Hedonic and Utilitarian Shopping Goals:The Online Experience显示文摘 | Eileen Bridges Renée Florsheim | 2008 | Journal of Business Research2008,61,4: | 1 |
| 11 | NF-E2-related factor 2,a key inducer of antioxidant defenses,negatively regulates the CFTR transcription显示文摘 | René C Lopez E Claustres M | | 0,,13: | 1 |
| 12 | Understanding the relationship between founder–CEOs and firm performance显示文摘 | Renée Adams Heitor Almeida Daniel Ferreira | 2008 | Journal of Empirical Finance2008,,1: | 1 |
| 13 | The identifi-cation of fiscal and monetary policy in a structural VAR显示文摘 | Mardi Dungey Renée Fry | 2009 | Economic Modelling In Press Corrected Proof Available online 23 June2009,2009,: | 1 |
| 14 | Financial returns, price determinants, and genre effects in American art investment显示文摘 | Richard J. Agnello Renée K. Pierce | 1996 | Journal of Cultural Economics1996,,4: | 1 |
| 15 | A Theory of Friendly Boards显示文摘 | RENéE B. ADAMS DANIEL FERREIRA | 2007 | The Journal of Finance2007,,1: | 1 |
| 16 | Social policy and the internal dynamics of the senior rights movement显示文摘 | Renée L. Beard John B. Williamson | 2010 | Journal of Aging Studies2010,,1: | 1 |
| 17 | Evaluation of potent odorants in heated egg yolk by aroma extract dilution analysis显示文摘 | Christoph Cerny Renée Guntz | 2004 | European Food Research and Technology2004,,5: | 1 |
| 18 | Dynamic simulation of brushless doubly-fed machines显示文摘 | Ruqi Li AlanWallace René Spée | 1991 | IEEE Transactions on Energy Conversion1991,6,3: | 1 |
| 19 | Is corporate governance different for bank holding companies显示文摘 | Adams Renée Hamid Mehran | | 0,,: | 1 |
| 20 | The diagnosis and man-agement of insomnia in clinical practice:apractical evidence-based approach显示文摘 | Anne MH Renée C Ann L | 2000 | CMAJ2000,162,2: | 1 |