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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | Tile role of microbial biofilms in deterioration of space station candidate materials 显示文摘 | GU J D ROMAN M ESSELMAN T | 1998 | Int Biodeterior Biodegrad1998，41，： | 1 |
| 3 | ATA practice guidelines for the treatment of differentiated thyroid cancer: were they followed in the United States? 显示文摘 | Famakinwa O M Roman S A Wang T S | 2010 | Am J Surg2010，199，2： | 1 |
| 4 | Relation of blood pressure variability to carotid atheroselerosis and carotid artery and left ventricular hypertrophy 显示文摘 | Roman M J Pickering T G Schwartz J E a al | 2001 | Arterioscler Thromb Vasc Biol2001，21，9： | 1 |
| 5 | EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis 显示文摘 | ALONSO J M HIRAYAMA T ROMAN G | 1999 | Science1999，284，5423： | 1 |
| 6 | Is the alpha - 2A adrener- gic receptor gene (ADRA2A) associated with attention deficit/hyper- activity disorder? 显示文摘 | Roman T Schmitz M Polanczyk GV | 2003 | Am J Med Genet2003，120，1： | 1 |
| 7 | Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene显示文摘 | Roman T Schmitz M Polanczyk GV | 2002 | Am J Med Genet2002，114，2： | 1 |
| 8 | The direct electrochemistry of cytochrome c at a hanging mercury drop electrode modified with 6-mercaptopurine显示文摘 | Sevilla J M Pineda T Roman A J | 1998 | Electroanalytical Chemistry1998，451，12： | 1 |
| 9 | A reference network model for large-scale distribution planning with automatic street map generation显示文摘 | DOMINGO C M ROMAN T G S SANCHEZ-MIRALLES A | 2011 | IEEE Transactions on Power Systems2011，26，1： | 1 |
| 10 | Is the alpha-2A adrenergic receptor gene (ADRA2A) associated with attention deficit/hyperactivity disorder 显示文摘 | Roman T Schmitz M Polanczyk G V | 2003 | Am J Med Genet2003，，1： | 1 |
| 11 | EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis 显示文摘 | Alonso J M Hirayama T Roman G | 1999 | Science1999，284，5423： | 1 |
| 12 | 显示文摘 | David M Roman T | 2007 | Surf Sci2007，601，： | 1 |
| 13 | Effect of sulfate groups from sulfuric acid hydrolysis on the thermal degradation behavior of bacterial cellulose显示文摘 | Roman M Winter W T | 2004 | Biomacromolecules2004，5，： | 1 |
| 14 | Association of carotid ahteors clo is and left ventricular hypertrophy显示文摘 | Roman M J Picketing T C Schwartz J E | 1995 | JAmColl Cardiol1995，25，1： | 1 |
| 15 | Staurosporine- induced apoptosis in cardiomyocytes: A potential role of caspase-3显示文摘 | YUE T L WANG C ROMANIC A M | 1998 | J Mol Cell Cardiol1998，30，3： | 1 |
| 16 | Relation of arterial structure and function to left ventricular geometric patterns in hypertensive adults显示文摘 | Roman M J Pickering T G Schwarts J E | 1996 | J Am Coll Cardiol1996，28，： | 1 |
| 17 | Relations of stroke volume and cardiac output to body composition: The strong heart study 显示文摘 | COLLIS T DEVEREUX R B ROMAN M J | 2001 | Circulation2001，103，6： | 1 |
| 18 | Lipofection: a highly efficient, lipid mediated DNA-transfection procedure显示文摘 | Felgner P L Gadek T R Holm M Roman R Chan H W Wenz M | 1987 | Proc Natl Acad Sci USA1987，84，： | 1 |
| 19 | Lactic acid bacteria isolated from a hand-made blue cheese显示文摘 | L6pez-Diaz T M Alonso C Roman C | 2000 | Food Microbiology2000，17，1： | 1 |
| 20 | State-space approach to spatially correlated MIMO OFDM channel estimation显示文摘 | ENESCU M ROMAN T KOIVUNEN V | | 0，，09： | 1 |
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