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| 1 | 无线技术促进健康显示文摘研究机构Global Wellness Institute 指出,在价值数万亿美元的大型产业中,“积极健康选择”( 即“维持健康”) 领域的消费将继续占有越来越大的比例,而无线技术领域就是其中的受惠产业之一。2020 年是新冠肺炎疫情COVID-19 首次产生大规模冲击的一年,但在此之前,一个强劲的行业已悄然启动,其焦点就是致力于改善大众健康的维持健康产业。 | Thomas Søderholm | 2021 | 电子产品世界2021，28，4： | 0 |
| 2 | 百年金康再启航显示文摘我们欣喜地看到,在整个国际标准制定过程中,中国发挥了主导作用,中国的贡献也将毫无疑问地提升GENCON 2022的代表性和实践性。 | Søren Larsen | 2022 | 中国远洋海运2022，，12： | 0 |
| 3 | Heterogeneity in neoadjuvant therapy for localized pancreatic cancer:a persisting radiant autonomy显示文摘Pancreatic cancer remains a disease with an overall grim prognosis,even in the limited number of patients who are amenable for resection attempted at cure.Indeed,pancreatic cancer demonstrate a predisposition for invasive growth and distant metastasis-even in the very early stages of the disease.Alas,while surgical resection is the strongest factor for long-term survival,early recurrence after surgery is associated with a poor prognosis(1).In light of this knowledge and,despite the lack of good level I data,it seems that patients and practitioners have been voting with their feet regarding systemic therapy;an increasing number of institutions are giving systemic treatment before surgery with the hopes of better disease control and avoiding futile surgery.However,the contemporary practice is based on an“radiant autonomy”-as it would seem,that pretty much any regimen and combination of drugs and modalities will be offered in current practice,with the lack of randomized studies for most options but often with an institutional signature to preference and delivery. | Kjetil Søreide | 2021 | Hepatobiliary Surgery and Nutrition2021，10，2： | 0 |
| 4 | Shadow Education in the Nordic Countries:An Emerging Phenomenon in Comparative Perspective显示文摘Since the turn of the century,expanding attention around the world has focused on the so-called shadow education system of private supplementary tutoring.The first global comparative study was authored by Bray(1999)and was titled The Shadow Education System:Private Supplementary Tutoring and its Implications for Planners.Bray employed the shadow metaphor for four reasons(p.17). | Søren Christensen 张薇 | 2021 | ECNU Review of Education2021，4，3： | 1 |
| 5 | Addressing the variation in hepatic surgery for colorectal liver metastasis显示文摘Introduction Liver surgery for colorectal liver metastasis(CRLM)has evolved considerably over the past two decades.Novel chemotherapy regimens and effective targeted therapy,changes in the view of resectability criteria and evolution of safer surgical principles have led to increasing resection rates and better overall survival for an increasing number of patients with stage IV colorectal cancer(1). | Rachel V.Guest Kjetil Søreide | 2021 | Hepatobiliary Surgery and Nutrition2021，10，1： | 0 |
| 6 | miRNA expression profiles in cerebrospinal fluid and blood of patients with Alzheimer’s disease and other types of dementia-an exploratory study显示文摘Background:MicroRNAs(miRNAs)are small non-coding RNA molecules that function as posttranscriptional regulators of gene expression.Measurements of miRNAs in cerebrospinal fluid(CSF)and blood have just started gaining attention as a novel diagnostic tool for various neurological conditions.The purpose of this exploratory investigation was to analyze the expression of miRNAs in CSF and blood of patients with Alzheimer’s disease(AD)and other neurodegenerative disorders in order to identify potential miRNA biomarker candidates able to separate AD from other types of dementia.Methods:CSF was collected by lumbar puncture performed on 10 patients diagnosed with AD and 10 patients diagnosed with either vascular dementia,frontotemporal dementia or dementia with Lewy bodies.Blood samples were taken immediately after.Total RNA was extracted from cell free fractions of CSF and plasma,and a screening for 372 known miRNA sequences was carried out by real time quantitative polymerase chain reactions(miRCURY LNA™Universal RT miRNA PCR,Polyadenylation and cDNA synthesis kit,Exiqon).Results:Fifty-two miRNAs were detected in CSF in at least nine out of ten patients in both groups.Among these,two miRNAs(let-7i-5p and miR-15a-5p)were found significantly up-regulated and one miRNA(miR-29c-3p)was found significantly down-regulated in patients with AD compared to controls.One hundred and sixty-eight miRNAs were frequently detected in the blood,among which miR-590-5p and miR-142-5p were significantly up-regulated and miR-194-5p was significantly down-regulated in AD patients compared to controls.Conclusions:Detection of miRNA expression profiles in blood and in particular CSF of patients diagnosed with different types of dementia is feasible and it seems that several expressional differences between AD and other dementia types do exist when measured in a clinically relevant setup.In this explorative pilot study,the deregulated miRNAs in CSF of AD patients may be associated with relevant target genes related to AD pathology,including APP and BACE1,which suggests that miRNAs are interesting candidates for AD biomarkers in the future. | Sofie Sølvsten Sørensen Ann-Britt Nygaard Thomas Christensen | 2016 | Translational Neurodegeneration2016，5，1： | 14 |
| 7 | Voltage regulation in LV grids by coordinated volt-var control strategies显示文摘The increasing penetration level of photovoltaic(PV)power generation in low voltage(LV)networks results in voltage rise issues,particularly at the end of the feeders.In order to mitigate this problem,several strategies,such as grid reinforcement,transformer tap change,demand-side management,active power curtailment,and reactive power optimization methods,show their contribution to voltage support,yet still limited.This paper proposes a coordinated volt-var control architecture between the LV distribution transformer and solar inverters to optimize the PV power penetration level in a representative LV network in Bornholm Island using a multi-objective genetic algorithm.The approach is to increase the reactive power contribution of the inverters closest to the transformer during overvoltage conditions.Two standard reactive power control concepts,cosu(P)and Q(U),are simulated and compared in terms of network power losses and voltage level along the feeder.As a practical implementation,a reconfigurable hardware is used for developing a testing platform based on real-time measurements to regulate the reactive power level.The proposed testing platform has been developed within PVNET.dk project,which targets to study the approaches for large PV power integration into the network,without the need of reinforcement. | Miguel JUAMPEREZ Guangya YANG Søren Bækhøj KJÆR | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，4： | 10 |
| 8 | 针吸术和切开引流术治疗急性单纯性肛周脓肿的随机对照研究显示文摘目的:采用针吸术治疗急性单纯性肛周脓肿在切口愈合、功能结局和生活质量方面具有潜在优势,或可作为传统切开引流术的替代方法。本研究的目的是比较针吸术联合术后抗生素使用与传统切开引流术治疗急性肛周脓肿的疗效。主要观察指标为脓肿复发情况,次要观察指标为瘘管形成、切口愈合、生活质量和肛门失禁情况。 | 佟伟华 SØRENSEN K M MÖLLER S QVIST N | 2021 | 结直肠肛门外科2021，27，2： | 6 |
| 9 | The development of machine learning-based remaining useful life prediction for lithium-ion batteries显示文摘Lithium-ion batteries are the most widely used energy storage devices,for which the accurate prediction of the remaining useful life(RUL)is crucial to their reliable operation and accident prevention.This work thoroughly investigates the developmental trend of RUL prediction with machine learning(ML)algorithms based on the objective screening and statistics of related papers over the past decade to analyze the research core and find future improvement directions.The possibility of extending lithium-ion battery lifetime using RUL prediction results is also explored in this paper.The ten most used ML algorithms for RUL prediction are first identified in 380 relevant papers.Then the general flow of RUL prediction and an in-depth introduction to the four most used signal pre-processing techniques in RUL prediction are presented.The research core of common ML algorithms is given first time in a uniform format in chronological order.The algorithms are also compared from aspects of accuracy and characteristics comprehensively,and the novel and general improvement directions or opportunities including improvement in early prediction,local regeneration modeling,physical information fusion,generalized transfer learning,and hardware implementation are further outlooked.Finally,the methods of battery lifetime extension are summarized,and the feasibility of using RUL as an indicator for extending battery lifetime is outlooked.Battery lifetime can be extended by optimizing the charging profile serval times according to the accurate RUL prediction results online in the future.This paper aims to give inspiration to the future improvement of ML algorithms in battery RUL prediction and lifetime extension strategy. | Xingjun Li Dan Yu Vilsen Søren Byg Store Daniel Ioan | 2023 | Journal of Energy Chemistry2023，，7： | 3 |
| 10 | 兆瓦级风力机结构系统可靠性分析的样本分数阶矩最大熵方法显示文摘以兆瓦级风力机塔架和叶片极限载荷的概率外推模型为基础,结合载荷动态响应峰值的独立同分布假设和三参数威布尔模型,外推获取了正常湍流和极端湍流强度条件下风力机关键部件长期服役载荷概率分布;进一步通过无量纲极值统计量定义系统失效的结构可靠性状态函数,结合样本分数阶矩和最大熵理论提出兆瓦级风力机关键部件结构可靠性分析的数值方法,对比湍流模型对兆瓦级风力机关键部件结构失效概率的影响。计算结果表明:样本分数阶矩最大熵方法能有效重构结构可靠性状态函数的概率分布;基于无量纲极值统计量的系统可靠性建模方法能有效表征风力机关键部件耦合相关失效问题,结合该文方法可获得系统失效概率的准确预测结果;湍流模型对风力机结构失效概率影响较大,难以预先判定何种模型将得到结构失效概率的保守预估结果,需结合IEC 61400-1标准中的设计载荷工况细致分析后才能确定。 | 黄德胜 张旭方 Sørensen John Dalsgaard | 2022 | 太阳能学报2022，43，7： | 2 |
| 11 | Understanding the effects of structured self-assessment in directed,self-regulated simulation-based training of mastoidectomy:A mixed methods study显示文摘Objective:Self-directed training represents a challenge in simulation-based training as low cognitive effort can occur when learners overrate their own level of performance.This study aims to explore the mechanisms underlying the positive effects of a structured self-assessment intervention during simulation-based training of mastoidectomy.Methods:A prospective,educational cohort study of a novice training program consisting of directed,self-regulated learning with distributed practice(5x3 procedures)in a virtual reality temporal bone simulator.The intervention consisted of structured self-assessment after each procedure using a rating form supported by small videos.Semi-structured telephone interviews upon completion of training were conducted with 13 out of 15 participants.Interviews were analysed using directed content analysis and triangulated with quantitative data on secondary task reaction time for cognitive load estimation and participants’self-assessment scores.Results:Six major themes were identified in the interviews:goal-directed behaviour,use of learning supports for scaffolding of the training,cognitive engagement,motivation from self-assessment,selfassessment bias,and feedback on self-assessment(validation).Participants seemed to self-regulate their learning by forming individual sub-goals and strategies within the overall goal of the procedure.They scaffolded their learning through the available learning supports.Finally,structured self-assessment was reported to increase the participants’cognitive engagement,which was further supported by a quantitative increase in cognitive load.Conclusions:Structured self-assessment in simulation-based surgical training of mastoidectomy seems to promote cognitive engagement and motivation in the learning task and to facilitate self-regulated learning. | Steven Arild Wuyts Andersen Martin Frendø Mads Guldager Mads Sølvsten Sørensen | 2020 | Journal of Otology2020，15，4： | 1 |
| 12 | Clinical valve thrombosis and subclinical leaflet thrombosis in transcatheter aortic heart valves:clinical manifestations,diagnosis,and treatment显示文摘During the last decade,transcatheter aortic valve replacement(TAVR)has rapidly expanded as an alternative to surgical aortic valve replacement(SAVR)in patients with symptomatic severe aortic valve stenosis(AS)and increased surgical risk.In TAVR,a bioprosthetic valve is positioned within the stenotic native aortic valve.Although favorable short-and medium-term outcomes have been reported,thrombosis of the transcatheter heart valve(THV)has occurred,with two different entities being described:clinical valve thrombosis and subclinical leaflet thrombosis.In clinical valve thrombosis,an increase in transvalvular gradient appears as a result of obstructive thrombus formation,which eventually leads to symptoms of heart failure.Subclinical leaflet thrombosis is an incidental finding,characterized by a thin layer of thrombus covering the aortic site of the leaflet—called hypoattenuating leaflet thickening(HALT)—as described on and defined by 4-dimensional computed tomography(4DCT)imaging.This phenomenon may affect motion of the leaflets and is then classified as hypo-attenuation affecting motion(HAM).Even in the case of HAM,the transvalvular pressure gradient remains within the normal range.Clinical valve thrombosis requires treatment,whereas the clinical impact and need for intervention in subclinical leaflet thrombosis is uncertain.Anticoagulant therapy protects against and resolves both clinical valve thrombosis and subclinical leaflet thrombosis,but studies exploring different antithrombotic strategies after TAVR are ongoing.This review summarizes currently available literature within the field of THV thrombosis and provides recommendations for a patient-tailored approach in TAVR patients,although guidelines are still lacking. | Liesbeth Rosseel Ole De Backer Lars Søndergaard | 2018 | Precision Clinical Medicine2018，1，3： | 0 |
| 13 | From preference to landscape sustainability:a bibliometric review of landscape preference research from 1968 to 2019显示文摘Landscape preference(LP)studies highlight one of the most important issues of human-environment relationship,and their related publications have increased rapidly over the last two decades.However,there is no systematic review with a holistic understanding of this field.here we applied a bibliometric approach to examine the evolution of LP research and identify its status and future prospects.We obtained 7,637 LP research publications from Web of Science core collection from 1968 to 2019 and analyzed the characteristics of publication outputs as well as performances in various countries and institutions.Besides,content keywords analysis was conducted to discover the drivers,focus,motivation,and trends of LP research.We found that 1)publications,subject categories,and active journals increased rapidly since the 2000s;2)the USA,England,and Australia are the leading countries in LP research,while China is starting to have some influence;3)LP research is most closely linked to ecological and environmental studies,being developed by objective drivers,i.e.,interactions with landscape change,and subjective motivations;and 4)LP research is advancing the landscape sustainability science,integrating natural and social science together through ecosystem services.By comprehensively reviewing the evolution and prospect of LP research,we provide insights for further research in this field. | Gaoyuan Yang Zhaowu Yu Jinguang Zhang Lone Søderkvist Kristensen | 2021 | Ecosystem Health and Sustainability2021，7，1： | 0 |
| 14 | 健康供者来源的TCR可以识别肿瘤新抗原显示文摘肿瘤新抗原(neoantigen)是一类因基因突变而编码出的新的未知蛋白质或多肽,以其良好的肿瘤特异性逐渐被科学家们所重视和利用,成为良好的肿瘤免疫治疗靶点。尽管在各种类型的肿瘤中发现了大量突变导致的肿瘤新抗原,但是真正能被患者免疫系统所识别的肿瘤新抗原不到1%。荷兰癌症研究所的Schumaeher和挪威奥斯陆大学的Olweus团队在癌症免疫疗法上取得新的突破,他们证实即使患者自身的T细胞不能够识别肿瘤新抗原和抵抗他们自身的肿瘤,但是其他人的T细胞可能可以识别。该研究成果发表在2016年6月的Science上。 | 虞淦军 万涛 StrØnen E Toebes M Kelderman S | 2016 | 中国肿瘤生物治疗杂志2016，23，5： | 0 |
| 15 | The prognostic relevance of examined lymph nodes for accurate staging of resected pancreatic adenocarcinoma显示文摘Pancreatic ductal adenocarcinoma(PDAC)is a disease with a particular aggressive cancer biology and,unfortunately,a very poor prognosis for most patients.There is no question about the lethality of pancreatic cancer.However,the question why this malignancy is so deadly remains a biological puzzle both to investigators and caretakers alike.Staging of pancreatic cancer undergoing resection-while important to compare cohorts across studies and trials-also allows for a clinical clue about the progress of the disease. | Claudia Zaharia Marcus Roalsø Kjetil Søreide | 2022 | Hepatobiliary Surgery and Nutrition2022，11，4： | 0 |
| 16 | Is there a survival benefit of a robotic approach to pancreatoduodenectomy for pancreatic cancer?显示文摘Pancreatic cancer has an overall poor prognosis,and only about 15%can be offered surgical resection.Current systemic therapy can achieve median overall survival rates up to 54 months,as reported in the PRODIGE-24 trial,for those who complete resection,have good performance status,a low carbohydrate antigen(CA)19-9 value and complete adjuvant therapy(1). | Dyre Kleive Sheraz Yaqub Kjetil Søreide | 2023 | Hepatobiliary Surgery and Nutrition2023，12，1： | 0 |
| 17 | Formation of RRR-a-tocopherol in rumen and intestinal digestibility of tocopherols in dairy cows显示文摘Tocopherol sources in diets are often a combination of all-rac-a-tocopheryl acetate(synthetic a-tocopherol)from vitamin supplements and natural tocopherols and 2R-(4’R,8’R)-5,7,8-trimethyltocotrienol(a-tocotrienols)from the feed sources.Synthetic a-tocopherol consists of 8 different stereoisomers including 2R-(4’R,8’R)-5,7,8-trimethyltocol(RRR-a-tocopherol),2R-(4’S,8’R)-5,7,8-trimethyltocol(RSR-a-tocopherol),2R-(4’R,8’S)-5,7,8-trimethyltocol(RRS-a-tocopherol),2R-(4’S,8’S)-5,7,8-trimethyltocol(RSS-a-tocopherol),2S-(4’S,8’S)-5,7,8-trimethyltocol(SSS-a-tocopherol),2S-(4’R,8’S)-5,7,8-trimethyltocol(SRS-a-tocopherol),2S-(4’S,8’R)-5,7,8-trimethyltocol(SSR-a-tocopherol),and2S-(4’R,8’R)-5,7,8-trimethyltocol(SRR-a-tocopherol).The pre-absorption metabolism of tocopherols and tocotrienols in ruminants differs from monogastric animals due to the extensive microbial fermentation in the anaerobic rumen.The current study investigated the impact of toasting and decortication of oats on metabolism in the digestive tract(synthesis,digestion),and intestinal digestibility of tocopherols in dairy cows by using 4 ruminal and intestinal cannulated Danish Holstein cows in a 4×4 Latin square design for 4 periods.Cows were fed a total mixed ration ad libitum containing different forms of oats:whole oat,decorticated oat,toasted oat,and decorticated toasted oat,all rolled before mixed ration.Overall means across 4 treatments were statistically analyzed,testing whether overall means were different from zero.Decortication or toasting did not affect the balance or digestibility of a-tocopherols in rumen.Average across treatments showed the ruminal degradation of synthetic a-tocopherol(279 mg/d,P=0.02;P-value shows that average across treatments is different from zero),synthetic 2R-a-tocopherol(133 mg/d,P<0.01;summation of RRS-,RSR-and RSS-a-tocopherol),and 2S-a-tocopherol(190 mg/d;P<0.01,summation of SSS-,SRS-,SSR,and SRR-a-tocopherol),while RRR-a-tocopherol was formed in the rumen(221 mg/d,P=0.10).The average across treatments showed that small intestinal digestibility of tocopherols ranked in the following order:a-tocotrienol>natural a-tocopherol>synthetic a-tocopherols>2R-(4’R,8’R)-,7,8-dimethyltocol(γ-tocopherol).The average across treatments for small intestinal and feed-ileum digestibility ranked in the following order:RRR-a-tocopherol>synthetic 2R-a-tocopherol>2S-a-tocopherol.Results showed the first evidence for RRR-a-tocopherol formation under anaerobic conditions in the rumen.In addition,synthetic a-tocopherol stereoisomers,γ-tocopherol and a-tocotrienol were degraded in the rumen.There was a discrimination against absorption of synthetic 2R-and 2S-a-tocopherol in the small intestine. | Saman Lashkari Farhad M.Panah Martin R.Weisbjerg Søren K.Jensen | 2023 | Animal Nutrition2023，，4： | 0 |
| 18 | The vascular endothelial growth factor system-a new player in the pathogenesis and development of metabolic dysfunction-associated steatotic liver disease显示文摘The pathogenesis of liver disease from simple steatosis-metabolic dysfunction-associated steatotic liver disease(MASLD)-and the transition to inflammation and fibrosis-metabolic dysfunction-associated steatohepatitis(MASH)-is not well understood.However,cross-talk between subcutaneous white adipose tissue(WAT)and the liver may be of importance. | Henning Grønbæk Anders Mellemkjær Søren Nielsen Faidon Magkos | 2023 | Hepatobiliary Surgery and Nutrition2023，12，6： | 0 |
| 19 | Extra-pair paternity and antiparasitic defence显示文摘Background:Extra-pair paternity(EPP)in birds provides benefits in terms of more offspring,and characteristics for maintenance of this behaviour have been the subject of investigation.Microorganisms are known to be transmitted during mating,especially when mating with multiple partners,and factors reducing this cost of multiple mating are expected.Further,plumage brightness and colour intensity have been shown to be important traits to benefits from multiple mating as predicted by sexual selection.The aim of this study was to investigate the relationship between the rate of extra-pair paternity and the relative size of the uropygial gland at the interspecific level,as the uropygial gland is an exocrine gland hypothesized to produce antiparasitic substances and further identified to affect plumage brightness.Because of the expected benefits of large uropygial gland in scenarios of sexual selection,we predicted a positive correlation with EPP.Methods:We collected information from the literature of uropygial gland size and frequency of extra-pair paternity of 60 avian species of different families and explored the predicted positive correlation between them.We did so with means of comparative analyses that considered phylogenetic relationship as random factor and included body mass as covariate.We used Markov chain Monte Carlo generalized linear mixed models that were weighted by number of nests used to estimate extra-pair paternity.Results:We detected a positive relationship between level of extra-pair paternity and uropygial gland size at an interspecific level.This finding is consistent with the prediction.Conclusions:We discuss the importance of this result in scenarios of sexual selection and argue that the detected relationship may have arisen by utilizing antiparasitic secretions through secondary sexual characters indicating parasite resistance. | Anders Pape Møller Jørgen Skavdal Søraker Juan JoséSoler | 2020 | Avian Research2020，11，4： | 0 |
| 20 | Application of the health risk assessment of acetochlor in the development of water quality criteria显示文摘Acetochlor is a widely used herbicide in agricultural production. Studies have shown that acetochlor has obvious environmental hormone effects, and long-term exposure may pose a threat to human health. To quantify the hazards of acetochlor in drinking water, a health risk assessment of acetochlor was conducted in major cities of China based on the data of acetochlor residue concentrations in drinking water. The approach of the Species Sensitivity Distributions(SSD) method is used to extrapolate from animal testing data to reflect worst case human toxicity. Results show that hazard quotients related to acetochlor residues in drinking water for different age groups range from 1.94 × 10-4 to 6.13 × 10-4, so, there are no indication of human risk. Compared to the total estimated hazard quotient from oral intake of acetochlor, the chronic exposure imputed to acetochlor residues in drinking water in China accounts for 0.4%. This paper recommends 0.02 mg/L to be the maximum acetochlor residue concentration level in drinking water and source water criteria. | Wei An Chenhui Sang Kristian Marienlund Jensen Peter Borgen Sørensen Bin Zhang Min Yang | 2021 | Journal of Environmental Sciences2021，33，12： | 2 |
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