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| 1 | Hypofractionated stereotactic rad iotherapy alone without whole-brain irradiation for patien ts with solitary and oligo brain metastasis using noninvasive fixation of the skull显示文摘To evaluate the efficacy and toxicity of hypofractionated stereotactic radiotherapy(HSRT)using noninvasive fixation of the sk ull on solitary or oligo brain metastatic p atients as an alternative to stereotactic radiosurgery(SRS)using invasive fixation.The subjects were 87patients who had 4or fewer brain meta stases(50solitary,37oligometastases).Treatment was conducted on 159meta stases by using a linac-based stereotactic system.T he median isocentric dose was 35Gy in4fractions.Whole-brain irradiati on was not applied as an initial treatment.For the salvage treatmen t of metachronous brain metastases,repeat HSRT or whole-brain irradiation was applied.The actuarial1-year local tumor control rate was 81%.Treatment-related complicatio ns were observed in 4patients in the e arly period(<3months)and in 2patients in the late period.T he median survival period was 8.7mon ths.Metachronous brain metastases occurred in 30patients,and none of the 18patients who were eligible for salvage HSRT refused to re ceive it again.Hypofractionated stereotactic radiotherapy achieved tumor control and survival equivalent to those of SRS reported i n the literature.The results suggested that HSRT could be an alternative for solitary or oligo br ain metastatic patients with less to xicity and less invasiveness compared to | Aoyama H Shirato H Onimaru R Kagei K Ikeda J Ishii N Sawamura Y Miyasaka K | 2003 | 癌症2003，22，7： | 12 |
| 2 | Tyrosinase inhibitory activity of citrus essential oils显示文摘 | MATSUURA R UKEDA H SAWAMURA M | 2006 | Journal of Agricultural and Food Chemistry2006，54，6： | 1 |
| 3 | Application of advances in molecular biology to the treatment of brain tumors显示文摘 | Takeshima H Sawamura Y Gilbert M R | 2000 | Curr Oncol Rep2000，2，5： | 1 |
| 4 | The role of G- protein-coupled receptor 120 in fatty acids sensing in chicken oral tissues 显示文摘 | Sawamura R Y Kawabata F Kawabata S | 2015 | Biochem Biophys Res Commun2015，458，2： | 1 |
| 5 | Tyrosinase inhibitor activity of citrus essential oils 显示文摘 | MATSUURA R UKEDA H SAWAMURA M | 2006 | Journal of Agricultural and Food Chemistry2006，6，54： | 1 |
| 6 | Antiviral activities of diarylheptanoids isolated from alpinia officinarum against respiratory syncytial virus, poliovirus, measles virus, and herpes simplex virus type 1 in vitro显示文摘 | Konno K Sawamura R Sun Y | 2006 | Natural Product Communications2006，6，12： | 1 |
| 7 | Mesoscale variability of verticalprofiles of environmental radionuclides ( 40K, 226 Ra, 210 Pb and137Cs) in temperate forest soils in Germany 显示文摘 | Fujiyoshi R Sawamura S | 2004 | Science of theTotal Environment2004，320，23： | 1 |
| 8 | Clinical heterogeneity of 1649delG mutation in the tail domain of keratin 5 : a Japanese family with epidermolysis bullosa simplex with mottled pigmentation 显示文摘 | Horiguchi Y Sawamura D Moil R | 2005 | J Invest Dermatol2005，125，1： | 1 |
| 9 | Dominant and recessive compound heterozygous mutations in epidermolysis bullosa simplex demonstrate the role of the stutter region in keratin intermediate filament assembly 显示文摘 | Yasukawa K Sawamura D McMillan J R | 2002 | J Biol Chem2002，277，23： | 1 |
| 10 | Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice 显示文摘 | Yamanaka K Hasegawa A Sawamura R | 1989 | Biochem Biophys Res Commun1989，165，： | 1 |
| 11 | Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice 显示文摘 | Yamanaka K Hasegawa A Sawamura R | 1991 | Toxicol Appl Pharmacol1991，108，2： | 1 |
| 12 | Effects of tetrabromobisphenol A, a brominated flame retardant, on the immune response to respiratory syncytial virus infection in mice 显示文摘 | Watanabe W Shimizu T Sawamura R | 2010 | lnt Immunopharmacol2010，10，4： | 1 |
| 13 | Clinical heterogeneity of 1649delG mutation in the taildomain ofkeratin 5:a Japanese family with epidermolysis bullosa simplex with mottled pigmentation显示文摘 | Horiguchi Y Sawamura D Mori R | 2005 | J Invest Dermatol2005，125，1： | 1 |
| 14 | Tyrosinase inhibitory activity of citrus essential oils显示文摘 | Matsuura R Ukeda H Sawamura M | 2006 | Journal Agricultural and Food Chemistry2006，54，6： | 1 |
| 15 | Antiatherogenic effects of novel lipoprotein lipase enhancing agent in cholesterol fed New Zealand white rabbits显示文摘 | Chiba T Miura S Sawamura F Uetsuka R Tomita I Inoue Y | 1997 | Ateroscler Thromb V asc Biol1997，17，： | 1 |
| 16 | Tyrosinase inhibitory activity of citrus essential oils 显示文摘 | Matsuura R Ukeda H Sawamura M | 2006 | Journal of Agricultural and Food Chemistry2006，54，6： | 1 |
| 17 | Tyrosinase inhibitory activity of citrus essential oils显示文摘 | MATSUURA R UKEDA H SAWAMURA M | | 0，，06： | 1 |
| 18 | Angiotensin Ⅱ increases the expression of lectin-like oxidized lox-density lipoprotein receptor-1 in human vascular smooth muscle cells via a lipoxygenase-dependent pathway显示文摘 | Limor R Kaplan M Sawamura T | 2005 | Am J Hypertens2005，18，3： | 1 |
| 19 | JAERI superconducting RF Linac-based free-electron laser-facility显示文摘 | Minehara E J Sawamura M Nagai R | | 0，，1： | 1 |
| 20 | JAERI superconducting RF linac-based free-electron laser-facility显示文摘 | Minehara E Sawamura M Nagai R | 2000 | Nucl Instr and Meth2000，445，： | 1 |
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