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| 1 | 缺血性脑卒中和出血性脑卒中患者发病前后血压的变化显示文摘《中国高血压防治指南2010》指出,急性脑卒中的血压处理缺乏足够的临床试验证据,参考建议如下:急性脑卒中溶栓前血压应控制在<185/110mm Hg(1mm Hg=0.133kPa)。对急性缺血性脑卒中发病24h内血压升高的患者应谨慎处理,收缩压≥180mm Hg或舒张压≥100mm Hg或伴有严重心功能不全、主动脉夹层、高血压脑病者,一般不予降压。降压的合理目标是24h内血压降低约15%。有高血压病史且正在服用降压药物者,如神经功能平稳,可于脑卒中发病后24h开始使用降压药物。因此,了解脑卒中患者发病前后的血压情况对临床治疗有重要的意义。Fischer等研究者探讨缺血性脑卒中和出血性脑卒中患者发病前后血压的变化情况。结果表明,缺血性脑卒中患者发病后首次测量的收缩压低于出血性脑卒中。与发病前比较,缺血性脑卒中发病后收缩压略升高(约10.6mm Hg),24h内轻度降低(约13.6mm Hg);而出血性脑卒中发病后,收缩压明显升高(约40.7mm Hg),24h内明显下降(约41.1mm Hg)。出血性脑卒中发病前几天及几周的平均收缩压逐渐增加,而缺血性脑卒中无明显变化。出血性脑卒中患者发病3h内的最高收缩压比发病前高50.0 mm Hg,而缺血性脑卒中则低5.2mm Hg。综上所述,与发病前比较,出血性脑卒中发病后收缩压升高,而缺血性脑卒中无明显变化。 | Fischer U Cooney MT Bull LM Silver LE Chalmers J Anderson CS Mehta Z Rothwell PM 林东杰 叶鹏 | 2014 | 中华高血压杂志2014，22，4： | 13 |
| 2 | Risk Factors for Posterior Compared to Anterior Ischemic Stroke: An Observational Study of the Registry of the Canadian Stroke Network显示文摘 | Subramanian G Silva J Silver F L Fang J Kapral M K Oczkowski W Gould L O’donnell M J | 2009 | Neuroepidemiology2009，，1： | 2 |
| 3 | Mechanisms of secondary hyperparathyroidism显示文摘 | Silver J Kilav R Naveh-Many T | | 0，，： | 2 |
| 4 | Effect of weekend admission on geriatric hip fractures显示文摘BACKGROUND The care discrepancy for patients presenting to a hospital on the weekend relative to the work week is well documented.With respect to hip fractures,however,there is no consensus about the presence of a so-called“weekend effect”.This study sought to determine the effects,if any,of weekend admission on care of geriatric hip fractures admitted to a large tertiary care hospital.It was hypothesized that geriatric hip fracture patients admitted on a weekend would have longer times to medical optimization and surgery and increased complication and mortality rates relative to those admitted on a weekday.AIM To determine if weekend admission of geriatric hip fractures is associated with poor outcome measures and surgical delay.METHODS A retrospective chart review of operative geriatric hip fractures treated from 2015-2017 at a large tertiary care hospital was conducted.Two cohorts were compared:patients who arrived at the emergency department on a weekend,and those that arrived at the emergency department on a weekday.Primary outcome measures included mortality rate,complication rate,transfusion rate,and length of stay.Secondary outcome measures included time from emergency department arrival to surgery,time from emergency department arrival to medical optimization,and time from medical optimization to surgery.RESULTS There were no statistically significant differences in length of stay(P=0.2734),transfusion rate(P=0.9325),or mortality rate(P=0.3460)between the weekend and weekday cohorts.Complication rate was higher in patients who presented on a weekend compared to patients who presented on a weekday(13.3%vs 8.3%;P=0.044).Time from emergency department arrival to medical optimization(22.7 h vs 20.0 h;P=0.0015),time from medical optimization to surgery(13.9 h vs 10.8 h;P=0.0172),and time from emergency department arrival to surgery(42.7 h vs 32.5 h;P<0.0001)were all significantly longer in patients who presented to the hospital on a weekend compared to patients who presented to the hospital on a weekday.CONCLUSION This study provided insight into the“weekend effect”for geriatric hip fractures and found that day of presentation has a clinically significant impact on delivered care. | Jordan B Pasternack Matthew L Ciminero Michael Silver Joseph Chang Ronald J Simon Kevin K Kang | 2020 | World Journal of Orthopedics2020，11，9： | 2 |
| 5 | Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells 显示文摘 | Murasawa S Levadot J Silver M | 2002 | Circulation2002，106，9： | 1 |
| 6 | Scavenger receptor-BI inhibits ATP-binding cassette transporter 1-mediated choles-terol efflux in macrophages显示文摘 | CHEN W SILVER D L SMITH J D | 2000 | J Biol Chem2000，275，30： | 1 |
| 7 | Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells显示文摘 | Murasawa S Llevadot J Silver M Isner JM Losordo DW Asahara T | 2002 | Circulation2002，106，9： | 1 |
| 8 | Frequency-modulation spectroscopy for tracespecies detection:theory and comparison among experi-mental methods显示文摘 | Silver J A | 1992 | Appl Opt1992，，31： | 1 |
| 9 | Editorial:PD-1,a new target for sepsis treatment:better late than never显示文摘 | Goyert SM Silver J | | 0，，02： | 1 |
| 10 | Selection of housekeeping genes for gene expression studies in human retieuloeytes using real-time PCR显示文摘 | SILVER N BEST S JIANG J | 2006 | BMC molecular biology2006，33，7： | 1 |
| 11 | Autotrophic growth of thiobacillus acidophilus in the presence of a surface-active agent, Tween-80显示文摘 | Kingma J G Jr Silver M | 1979 | Applied and Environmental Microbiology1979，38，5： | 1 |
| 12 | Bacterial resistance mechanism for heavy metal of environmental concern 显示文摘 | Silvers J I G | 1995 | Ind Microbiol1995，14，： | 1 |
| 13 | Adenosine mediated relaxation and activation of cyclic AMP dependent protein kinase in coronary arterial smooth muscle显示文摘 | Walus K Disalvo J | 1984 | J Pharmacol Exp Ther1984，228，： | 1 |
| 14 | Reliability of the Visual Analog Scale for Measurement of Acute Pain显示文摘 | Bijur P E Silver W Gallagher E J | 2001 | Acad Emerg Med2001，8，12： | 1 |
| 15 | Plant and microbial controls on nitrogen retention and loss in a humid tropical forest显示文摘 | Templer P H Silver W L Pett-Ridge DeAngelis J M K Firestone MK | 2008 | Ecology2008，89，11： | 1 |
| 16 | Direct evidence of endothelial oxidative stress with aging in humans:relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB显示文摘 | Donato A J Eskurza I Silver AE | | 0，，11： | 1 |
| 17 | FGF23 and PTH-donb- le agents at the heart of CKD显示文摘 | Silver J Rodriguez M Slatopolsky E | 2012 | Nephrol Dial Transplant2012，27，5： | 1 |
| 18 | Regeneration of adult axons in white matter tracts of the central nervous system显示文摘 | Davies S J Fitch M T Memberg S P Hall A K Raisman G Silver J | 1997 | Nature1997，390，： | 1 |
| 19 | Raman spectra of earotenoids in natural products显示文摘 | Withnall R Chowdhry B Z Silver J | 2003 | Spectrochimica Acta Part A2003，59，： | 1 |
| 20 | Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development显示文摘 | Gibson-Brown J J Agulnik S I Silver L M | 1998 | Development1998，125，13： | 1 |
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