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| 1 | Vascular depression for radiology: A review of the construct,methodology,and diagnosis显示文摘Vascular depression(VD)as defined by magnetic resonance imaging(MRI)has been proposed as a unique subtype of late-life depression.The VD hypothesis posits that cerebrovascular disease,as characterized by the presence of MRIdefined white matter hyperintensities,contributes to and increases the risk for depression in older adults.VD is also accompanied by cognitive impairment and poor antidepressant treatment response.The VD diagnosis relies on MRI findings and yet this clinical entity is largely unfamiliar to neuroradiologists and is rarely,if ever,discussed in radiology journals.The primary purpose of this review is to introduce the MRI-defined VD construct to the neuroradiology community.Case reports are highlighted in order to illustrate the profile of VD in terms of radiological,clinical,and neuropsychological findings.A secondary purpose is to elucidate and elaborate on the measurement of cerebrovascular disease through visual rating scales and semi-and fully-automated volumetric methods.These methods are crucial for determining whether lesion burden or lesion severity is the dominant pathological contributor to VD.Additionally,these rating methods have implications for the growing field of computer assisted diagnosis.Since VD has been found to have a profile that is distinct from other types of late-life depression,neuroradiologists,in conjunction with psychiatrists and psychologists,should consider VD in diagnosis and treatment planning. | Sara N Rushia Al Amira Safa Shehab Jeffrey N Motter Dakota A Egglefield Sophie Schiff Joel R Sneed Ernst Garcon | 2020 | World Journal of Radiology2020，12，5： | 5 |
| 2 | Ribavirin:Past,present and future显示文摘Before the advent of direct acting antiviral agents(DAAs) ribavirin, associated to pegylated-interferon played a crucial role in the treatment of chronic hepatitis C, preventing relapses and breakthroughs. In the present era of new potent DAAs, a place is still devoted to the drug. Ribavirin associated with sofosbuvir alone is efficient in the treatment of most cases of G2 infected patients. All options currently available for the last difficult-to-treat cirrhotic G3 patients contain ribavirin. Reducing treatment duration to 12 wk in G1 or G4 cirrhotic compensated patients is feasible thanks to ribavirin. Retreating patients with acquired anti NS5 A resistance-associated variants using ribavirin-based strategies could be useful. The addition of ribavirin with DAAs combinations however, leads to more frequent but mild adverse events especially in cirrhotic patients. Preliminary data with interferon-free second generation DAAs combinations without ribavirin suggest that future of the drug is jeopardized even in difficult-totreat patients: The optimization of ribavirin dosage according to an early monitoring of blood levels has been suggested to be relevant in double therapy with peginterferon or sofosbuvir but not with very potent combinations of more than two DAAs. | Véronique Loustaud-Ratti Marilyne Debette-Gratien Jérémie Jacques Sophie Alain Pierre Marquet DenisSautereau Annick Rousseau Paul Carrier | 2016 | World Journal of Hepatology2016，8，2： | 3 |
| 3 | HCV ‐associated B ‐cell non‐ H odgkin lymphomas and new direct antiviral agents显示文摘 | Paul Carrier Arnaud Jaccard Jérémie Jacques Tessa Tabouret Marilyne Debette‐Gratien Julie Abraham Laura Mesturoux Pierre Marquet Sophie Alain Denis Sautereau Marie Essig Véronique Loustaud‐Ratti | 2015 | Liver Int2015，，10： | 2 |
| 4 | Towards a new tuberculosis drug: pyridomycin – nature’s isoniazid显示文摘 | Ruben C. Hartkoorn Claudia Sala Jo?o Neres Florence Pojer Sophie Magnet Raju Mukherjee Swapna Uplekar Stefanie Boy‐R?ttger Karl‐Heinz Altmann Stewart T. Cole | 2012 | EMBO Mol Med2012，，： | 2 |
| 5 | Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation显示文摘 | Céline Chu Marie‐Sophie No?l‐Hudson Valérie Boige Diane Goéré Sylvie Marion Mélanie Polrot Ludovic Bigot Patrick Gonin Robert Farinotti Laurence Bonhomme‐Faivre | 2013 | Fundamental & Clinical Pharmacology2013，，4： | 2 |
| 6 | Al/stainless - invar com- posites with tailored anisotropy for thermal management in light weight electronic packaging 显示文摘 | Sophie R Anne M Francis D | 2015 | Materials and De- sign2015，85，： | 1 |
| 7 | Treatment of Sleep Problems in a 5-year-old Boy with Autism Using Behavioural Principles显示文摘 | Sophie W Jan M Amanda R | 2001 | Autism2001，，2： | 1 |
| 8 | Primary Culture of Human Atrial Myocytes is Associated with the Appearance of Structural and Functional Characteristics of Immature Myocardium显示文摘 | Agnès Bénardeau Stéphane N. Hatem Catherine Rücker-Martin Sophie Tessier Sylvie Dinanian Jane-Lyse Samuel Edouard Coraboeuf Jean-Jaques Mercadier | 1997 | Journal of Molecular and Cellular Cardiology1997，，5： | 1 |
| 9 | The effect of density on sea bass (Dicentrarchus labrax ) performance in a tank-based recirculating system显示文摘 | SOPHIE S EMMANUELLE R ERIC G | 2009 | Aquacuhural Engineering2009，40，2： | 1 |
| 10 | Allelopathic potential of Medicago arborea, a mediterranean invasive shrub 显示文摘 | ANNE B M SOPHIE L CHRISTINE R S G | 2005 | Chem Ecology2005，5，： | 1 |
| 11 | The regionalization of PepT1,NBAT and unchanged from birth to adulthood 显示文摘 | Sophie R Barbot L Windsor E | 2002 | Nutr2002，132，： | 1 |
| 12 | Expanding the Role of the Nurse Practitioner in the Deployed Setting显示文摘 | Julie Dargis Theresa Horne Sophie Tillman-Ortiz r | 2006 | Mil-Med2006，171，8： | 1 |
| 13 | Volcanic carbon dioxide vents show ecosystem effects of ocean acidification显示文摘 | JASON M H RICCARDO R M SOPHIE M | 2008 | Nature2008，454，： | 1 |
| 14 | Low-grade inflammation, obesity, and insulin resistance in adolescents 显示文摘 | Christian H Sophie S Wolfgang R | 2007 | J Clin Endocrinol Melab2007，92，9： | 1 |
| 15 | Effects of norepinephrine and dobutamine on pressure load - induced right ventricolar failure 显示文摘 | Francois K Benoit R Sophie M | 2004 | Crit Care Med2004，32，4： | 1 |
| 16 | Methods for synthesizing diethyl carbonate from ethanol and supercritical carbon dioxide by one-pot or two-step reactions in the presence of potassium carbonate显示文摘 | Fabien G Sophie T R Zephirin M | 2009 | The Journal of Supercritical Fluids2009，50，1： | 1 |
| 17 | Endogenous control 0f hippocampal epileptogenesis:a molecular cascade involving BDNF and NPY显示文摘 | Sophie R Yves L Josette C et a1 | 2000 | Epilepsia2000，6，： | 1 |
| 18 | Passive optical fast frequcncy-hop CDMA communications system显示文摘 | FATHALLAH H LESLIE A R SOPHIE L | 1999 | Journal of Lighwave Technology1999，17，3： | 1 |
| 19 | Low - grade inflammation, obesity, and insulin resistance in adolescents 显示文摘 | Christian H Sophie S Wolfgang R | 2007 | J Clin Endocrinol Metab2007，92，9： | 1 |
| 20 | Pecking order and debt capacity considerations for high-growth companies seeking financing显示文摘 | TOM R VANACKER SOPHIE MANIGART | 2010 | Small Business Economics2010，35，1： | 1 |
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