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| 1 | Activation of Defense Response Pathways by OGs and Fig22 Elicitors in Arabidopsis Seedlings显示文摘 | Carine Denoux Roberta Galletti Nicole Mammarella Suresh Gopalan Danièle Werck Giulia De Lorenzo Simone Ferrari Frederick M. Ausubel Julia Dewdney | 2008 | Molecular Plant2008，1，3： | 13 |
| 2 | Technical and conceptual considerations forusing animated stimuli in studies of animalbehavior显示文摘Rapid technical advances in the field of computeropened new avenues in animal behavior research.animation (CA) and virtual reality (VR) haveAnimated stimuli are powerful tools as theyoffer standardization, repeatability, and complete control over the stimulus presented, thereby"reducing" and "replacing" the animals used, and "refining" the experimental design in line withthe 3Rs. However, appropriate use of these technologies raises conceptual and technical questions.In this review, we offer guidelines for common technical and conceptual considerations related tothe use of animated stimuli in animal behavior research. Following the steps required to create ananimated stimulus, we discuss (I) the creation, (11) the presentation, and (111) the validation of CAsand VRs. Although our review is geared toward computer-graphically designed stimuli, consider-ations on presentation and validation also apply to video playbacks. CA and VR allow both new be-havioral questions to be addressed and existing questions to be addressed in new ways, thus weexpect a rich future for these methods in both ultimate and proximate studies of animal behavior. | Laura CHOUINARD-THULY Stefanie GIERSZEWSKI Gil G. ROSENTHAL Simon M. READER Guillaume RIEUCAU Kevin L. Woo Robert GERLAI Cynthia TEDORE Spencer J. INGLEY John R. STOWERS Joachim G.FROMMENI Francine L. DOLINS Klaudia WITTE | 2017 | Current Zoology2017，63，1： | 10 |
| 3 | The Clock Protein CCA1 and the bZIP Transcription Factor HY5 Physically Interact to Regulate Gene Expression in Arabidopsis显示文摘生理节奏的钟调整象编码轻收获的叶绿素 A/B (Lhcb ) 的那些那样的一连串的 Arabidopsis 基因的表示蛋白质。我们以前学习了二这些 Arabidopsis genesLhcb1 *1 的倡导者, Lhcb1 *3and 识别了绑钟蛋白质的一个序列联系的生理节奏的钟 1 (CCA1 ) 。这个序列,指明的 CCA1 有约束力的地点(CBS ) ,为 phytochrome 和这些基因的生理节奏的应答是必要的。在到这个序列的靠近的最近,在那里存在被显示了在另外的调整光的植物倡导者绑 bZIP 抄写因素 HY5 的一个 G 盒子核心元素。在现在的学习,我们检验了抄写因素绑定的相互作用的重要性在 Lhcb 基因的正常生理节奏的有韵律的表示的控制的 CBS 和 G 盒子核心元素。我们的结果证明 HY5 能明确地在 Lhcb 倡导者绑 G 盒子元素并且 CCA1 能改变 HY5 的有约束力的活动。我们进一步证明 CCA1 和 HY5 罐头身体上交往并且他们能在酵母记者基因试金对抄写 synergistically 起作用。HY5 的缺席导致 Lhcb1 *1 的一个更短的时期生理节奏的表示但是不影响 CATALASE3 (CAT3 ) 的生理节奏的表示,其倡导者缺乏一个 G 盒子元素。我们的结果建议 Lhcb 倡导者上的 HY5 和 CCA1 蛋白质的那个相互作用为 Lhcb 基因的正常生理节奏的表示是必要的。 | Christos Andronis Simon Barak Stephen M. Knowles Shoji Sugano Elaine M. Tobin | 2008 | Molecular Plant2008，1，1： | 9 |
| 4 | Towards maximized utilization of iridium for the acidic oxygen evolution reaction显示文摘The reduction in noble metal content for efficient oxygen evolution catalysis is a crucial aspect towards the large scale commercialisation of polymer electrolyte membrane electrolyzers.Since catalytic stability and activity are inversely related,long service lifetime still demands large amounts of low-abundant and expensive iridium.In this manuscript we elaborate on the concept of maximizing the utilisation of iridium for the oxygen evolution reaction.By combining different tin oxide based support materials with liquid atomic layer deposition of iridium oxide,new possibilities are opened up to grow thin layers of iridium oxide with tuneable noble metal amounts.In-situ,time-and potential-resolved dissolution experiments reveal how the stability of the substrate and the catalyst layer thickness directly affect the activity and stability of deposited iridium oxide.Based on our results,we elaborate on strategies how to obtain stable and active catalysts with maximized iridium utilisation for the oxygen evolution reaction and demonstrate how the activity and durability can be tailored correspondingly.Our results highlight the potential of utilizing thin noble metal films with earth abundant support.materials for future catalytic applications in the energy sector. | Marc Ledendecker Simon Geiger Katharina Hengge Joohyun Lim Serhiy Cherevko Andrea M. Mingers Daniel Gohl Guilherme V. Fortunato Daniel Jalalpoor Ferdi Schuth Christina Scheu Karl J. J. Mayrhofer | 2019 | Nano Research2019，12，9： | 6 |
| 5 | Inferring the Tree of Life of the order Cypriniformes, the earth's most diverse clade of freshwater fishes: Implications of varied taxon and character sampling显示文摘The phylogenetic relationships of species are fundamental to any biological investigation, including all evolutionary studies. Accurate inferences of sister group relationships provide the researcher with an historical framework within which the attributes or geographic origin of species (or supraspecific groups) evolved. Taken out of this phylogenetic context, interpretations of evolutionary processes or origins, geographic distributions, or speciation rates and mechanisms, are subject to nothing less than a biological experiment without controls. Cypriniformes is the most diverse clade of freshwater fishes with estimates of diversity of nearly 3,500 species. These fishes display an amazing array of morphological, ecological, behavioral, and geographic diversity and offer a tremendous opportunity to enhance our understanding of the biotic and abiotic factors associated with diversification and adaptation to environments. Given the nearly global distribution of these fishes, they serve as an important model group for a plethora of biological investigations, including indicator species for future cli-matic changes. The occurrence of the zebrafish, Danio rerio, in this order makes this clade a critical component in understanding and predicting the relationship between mutagenesis and phenotypic expressions in vertebrates, including humans. With the tremendous diversity in Cypriniformes, our understanding of their phylogenetic relationships has not proceeded at an acceptable rate, despite a plethora of morphological and more recent mo-lecular studies. Most studies are pre-Hennigian in origin or include relatively small numbers of taxa. Given that analyses of small numbers of taxa for molecular characters can be compromised by peculiarities of long-branch attraction and nodal-density effect, it is critical that significant progress in our understanding of the relationships of these important fishes occurs with increasing sampling of species to mitigate these potential problems. The recent Cypriniformes Tree of Life initiative is an effort to achieve this goal with morphological and molecular (mitochondrial and nuclear) data. In this early synthesis of our understanding of the phylogenetic relationships of these fishes, all types of data have contributed historically to improving our understanding, but not all analyses are complementary in taxon sampling, thus precluding direct understanding of the impact of taxon sampling on achieving accurate phylogenetic inferences. However, recent molecular studies do provide some insight and in some instances taxon sampling can be implicated as a variable that can influence sister group relationships. Other instances may also exist but without inclusion of more taxa for both mitochondrial and nuclear genes, one cannot distinguish between inferences being dictated by taxon sampling or the origins of the molecular data. | Richard L. MAYDEN Kevin L. TANG Robert M. WOOD Wei-Jen CHEN Mary K. AGNEW Kevin W. CONWAY Lei YANG Andrew M. SIMONS Henry L. BART Phillip M. HARRIS Junbing LI Xuzhen WANG Kenji SAITOH Shunping HE Huanzhang LIU Yiyu CHEN Mutstmi NISHIDA Masaki MIYA | 2008 | 植物分类学报2008，46，3： | 5 |
| 6 | Executive Summary: Heart Disease and Stroke Statistics— 2010 Update: A Report From the American Heart Association显示文摘 | Donald Lloyd-Jones Robert J. Adams Todd M. Brown Mercedes Carnethon Shifan Dai Giovanni De Simone T. Bruce Ferguson Earl Ford Karen Furie Cathleen Gillespie Alan Go Kurt Greenlund Nancy Haase Susan Hailpern P. Michael Ho Virginia Howard Brett Kissela Stev | 2010 | Circulation2010，，7： | 5 |
| 7 | Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association显示文摘 | Véronique L. Roger Alan S. Go Donald M. Lloyd-Jones Robert J. Adams Jarett D. Berry Todd M. Brown Mercedes R. Carnethon Shifan Dai Giovanni de Simone Earl S. Ford Caroline S. Fox Heather J. Fullerton Cathleen Gillespie Kurt J. Greenlund Susan M. Hailpern | 2011 | Circulation2011，，4： | 4 |
| 8 | Incubation Phase of Acute Hepatitis B in Man: Dynamic of Cellular Immune Mechanisms显示文摘 | George J.M. Webster Stephanie Reignat Mala K. Maini Simon A. Whalley Graham S. Ogg Abigail King David Brown Peter L. Amlot Roger Williams Diego Vergani Geoffrey M. Dusheiko Antonio Bertoletti | 2000 | Hepatology2000，，5： | 4 |
| 9 | The Diagnostic Approach to Monogenic Very Early Onset Inflammatory Bowel Disease显示文摘 | Holm H. Uhlig Tobias Schwerd Sibylle Koletzko Neil Shah Jochen Kammermeier Abdul Elkadri Jodie Ouahed David C. Wilson Simon P. Travis Dan Turner Christoph Klein Scott B. Snapper Aleixo M. Muise | 2014 | Gastroenterology2014，，： | 3 |
| 10 | Models of withdrawing renewable and non-renewable resources based on Odum’s energy systems theory and Daly’s quasi-sustainability principle显示文摘 | Simone Bastianoni Riccardo M. Pulselli Federico M. Pulselli | 2009 | Ecological Modelling2009，，16： | 3 |
| 11 | 高血压患者左室向心性结构与舒张功能减退相关:HyperGEN研究 | De Simone G. Kitzman D. W. Chinali M. 郭战宏 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005，0，10： | 2 |
| 12 | Cytoreduction and HIPEC in The Netherlands: Nationwide Long-term Outcome Following the Dutch Protocol显示文摘 | Anke M. J. Kuijpers Boj Mirck Arend G. J. Aalbers Simon W. Nienhuijs Ignace H. J. T. Hingh Martinus J. Wiezer Bert Ramshorst Robert J. Ginkel Klaas Havenga Andreas J. Bremers Johannes H. W. Wilt Elisabeth A. Velde Vic J. Verwaal | 2013 | Annals of Surgical Oncology2013，，13： | 2 |
| 13 | Prediction of Mean Circulation Velocity in Oxidation Ditch显示文摘 | S. Simon M. Roustan J. M. Audic P. Chatellier | 2001 | Environmental Technology2001，，2： | 2 |
| 14 | Carotenoid biosynthesis structural genes in carrot ( Daucus carota ): isolation, sequence-characterization, single nucleotide polymorphism (SNP) markers and genome mapping显示文摘 | B. J. Just C. A. F. Santos M. E. N. Fonseca L. S. Boiteux B. B. Oloizia P. W. Simon | 2007 | Theoretical and Applied Genetics2007，，4： | 2 |
| 15 | Long-Term Morbidity and Oncologic Outcomes of Laparoscopic-Assisted Anterior Resection for Upper Rectal Cancer: Ten-Year Results of a Prospective, Randomized Trial显示文摘 | Simon S. M. Ng Ka Lau Leung Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Sophie S. F. Hon | 2009 | Diseases of the Colon & Rectum2009，，： | 2 |
| 16 | Comparative Effectiveness for Survival and Renal Function of Partial and Radical Nephrectomy for Localized Renal Tumors: A Systematic Review and Meta-Analysis显示文摘 | Simon P. Kim R. Houston Thompson Stephen A. Boorjian Christopher J. Weight Leona C. Han M. Hassan Murad Nathan D. Shippee Patricia J. Erwin Brian A. Costello George K. Chow Bradley C. Leibovich | 2012 | The Journal of Urology2012，，： | 2 |
| 17 | Double Balloon Enteroscopy Detects Small Bowel Mass Lesions Missed by Capsule Endoscopy显示文摘 | Andrew Ross Shahab Mehdizadeh Jeffrey Tokar Jonathan A. Leighton Ahmad Kamal Ann Chen Drew Schembre Gary Chen Kenneth Binmoeller Richard Kozarek Irving Waxman Charles Dye Lauren Gerson M. Edwyn Harrison Oleh Haluszka Simon Lo Carol Semrad | 2008 | Digestive Diseases and Sciences2008，，8： | 2 |
| 18 | Hypoxia-Inducible Factors, Stem Cells, and Cancer显示文摘 | Brian Keith M. Celeste Simon | 2007 | Cell2007，，3： | 2 |
| 19 | SJES14121800014225显示文摘 | Amar J. Majmundar Waihay J. Wong M. Celeste Simon | 2010 | Molecular Cell2010，，： | 2 |
| 20 | What is the learning curve associated with double-balloon enteroscopy? Technical details and early experience in 6 U.S. tertiary care centers <ce:link locator='fx1'/>显示文摘 | Shahab Mehdizadeh Andrew Ross Lauren Gerson Jonathan Leighton Ann Chen Drew Schembre Gary Chen Carol Semrad Ahmad Kamal Edwyn M. Harrison Kenneth Binmoeller Irving Waxman Richard Kozarek Simon K. Lo | 2006 | Gastrointestinal Endoscopy2006，，5： | 2 |
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