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37篇 您的检索式:作者名="Sperlagh"
    题名 作者 年代 出处 被引量
1Non-synaptic release of noradrenaline in response to oxidative stress combined with mitochondrial dysfunction in rat hippocampal slices显示文摘 Sperlagh B Shikova L 2003Neuroscience2003,120,:1
2P2X7 receptors in the nervous system显示文摘Sperlagh B Vizi E S Wirkner K 2006Prog Neurobiol2006,78,6:1
3From purines to purinergic signalling:molecular functions and human diseases显示文摘Purines and their derivatives,most notably adenosine and ATP,are the key molecules controlling intracellular energy homoeostasis and nucleotide synthesis.Besides,these purines support,as chemical messengers,purinergic transmission throughout tissues and species.Purines act as endogenous ligands that bind to and activate plasmalemmal purinoceptors,which mediate extracellular communication referred to as“purinergic signalling”.Purinergic signalling is cross-linked with other transmitter networks to coordinate numerous aspects of cell behaviour such as proliferation,differentiation,migration,apoptosis and other physiological processes critical for the proper function of organisms.Pathological deregulation of purinergic signalling contributes to various diseases including neurodegeneration,rheumatic immune diseases,inflammation,and cancer.Particularly,gout is one of the most prevalent purine-related disease caused by purine metabolism disorder and consequent hyperuricemia.Compelling evidence indicates that purinoceptors are potential therapeutic targets,with specific purinergic agonists and antagonists demonstrating prominent therapeutic potential.Furthermore,dietary and herbal interventions help to restore and balance purine metabolism,thus addressing the importance of a healthy lifestyle in the prevention and relief of human disorders.Profound understanding of molecular mechanisms of purinergic signalling provides new and exciting insights into the treatment of human diseases.Zhao Huang Na Xie Peter Illes Francesco Di Virgilio Henning Ulrich Alexey Semyanov Alexei Verkhratsky Beata Sperlagh Shu-Guang Yu Canhua Huang Yong Tang 2021Signal Transduction and Targeted Therapy2021,6,5:1
4Immunization procedures for anti-idiotypic antibody induction in mice and rats 显示文摘Maruyama H Sperlagh M Zaloudik J et d 2002J Immunol Methods2002,264,12:1
5P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus 显示文摘Papp L Vizi ES Sperlagh B 2007Biochem and Bioph Res Co2007,355,2:1
6P2Xs receptor involvement in pain states显示文摘Wirkner K Sperlagh B Illes P 2007Mol Neurobiol2007,36,:1
7Lack of ATP- evoked GABA and gluta- mate release in the hippocampus of P2X7 receptor -/- mice显示文摘Vizi E S Sperlagh B 2004Neuroreport2004,15,15:1
8P2X7 receptor: an emerging target in central nervous system diseases 显示文摘Sperlagh B llles P 2014Trends in pharmacological sciences2014,35,10:1
9Peripheral origin of IL-1β production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X7 receptors 显示文摘Csolle C Sperlagh B 2010J Neuroimmunol2010,219,12:1
10The role of puri- nergic signaling in depressive disorders显示文摘SPERLAGH B CSOLLE C ANDO R D 2012Neuropsychophar- macol Hung2012,14,4:1
11P2X7 receptors in thenervous system显示文摘Sperlagh B Vizi E S Wirkner K Illes P 2006Prog Neurob2006,78,:1
12Modulation of norepinephrine release by ATP-dependent K+-channel activators and inhibitors in guinea-pig and human isolated right atrium显示文摘 Sperlagh B Santha E 1999Cardiovasc Res1999,43,1:1
13The role of extracellular adenosine inchemical neurotransmission in the hippocampus and Basal Ganglia: pharmacologi- cal and clinical aspects 显示文摘Sperlagh B Vizi ES 2011CurrTop Med Chem2011,11,:1
14The role of purinergic signaling in depressive disorders显示文摘Sperlagh B Csolle C Ando RD 2012Neuropsychopharmacol Hung2012,14,4:1
15Modulation of norepinephrine release by ATP-dependent K+-channel activators and inhibitors in guinea-pig and human isolated right atrium显示文摘Oe K Sperlagh B Santha E 1999Cardiovasc Res1999,43,:1
16P2X3 receptor involvement in pain states显示文摘Wirkner K Sperlagh B Illes P 2007MolNeurobinl2007,36,2:1
17P2X 7 receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBC rds mice显示文摘Heike Franke Kerstin Klimke Ute Brinckmann Jens Grosche Mike Francke Beata Sperlagh Andreas Reichenbach Uwe Gerd Liebert Peter Illes 2005Neurochemistry International2005,,4:1
18P2X7 receptors in the nervous system显示文摘Sperlagh B Vizi B Wirkner K 2006Prog Neurobiol2006,78,6:1
19P2X7 receptors in the nervous system显示文摘Sperlagh B Vizi ES Wirkner K 2006Prog Neurobiol2006,78,6:1
20The role of extracellular adenosine inchemical neurotransmission in the hippocampus and BasalGanglia : pharmacological and clinical aspects 显示文摘Sperlagh B Vizi ES 2011CurrTop Med Chem2011,11,:1
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