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| 1 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 2 | What every gastroenterologist needs to know about common anorectal disorders显示文摘Anorectal complaints are very common and are caused by a variety of mostly benign anorectal disorders.Many anorectal conditions may be successfully treated by primary care physicians in the outpatient setting,but patients tend not to seek medical attention due to embarrassment or fear of cancer.As a result,patients frequently present with advanced disease after experiencing significant decreases in quality of life.A number of patients with anorectal complaints are referred to gastroenterologists.However,gastroenterologists' knowledge and experience in approaching these conditions may not be sufficient.This article can serve as a guide to gastroenterologists to recognize,evaluate,and manage medically or non-surgically common benign anorectal disorders,and to identify when surgical referrals are most prudent.A review of the current literature is performed to evaluate comprehensive clinical pearls and management guidelines for each topic.Topics reviewed include hemorrhoids,anal fissures,anorectal fistulas and abscesses,and pruritus ani. | Moonkyung Cho Schubert Subbaramiah Sridhar Robert R Schade Steven D Wexner | 2009 | World Journal of Gastroenterology2009，15，26： | 5 |
| 3 | Glass and Mineral Chemistry of Northern Central Indian Ridge Basalts:Compositional Diversity and Petrogenetic Significance显示文摘The glass and mineral chemistry of basalts examined from the northern central Indian ridge (NCIR) provides an insight into magma genesis around the vicinity of two transform faults: Vityaz (VT) and Vema (VM). The studied mid-ocean ridge basalts (MORBs) from the outer ridge flank (VT area) and a near-ridge seamount (VM area) reveal that they are moderately phyric plagioclase basalts composed of plagioclase (phenocryst [An60-90] and groundmass [An35-79]), olivine (Fo81-88), diopside (Wo45-51, En25-37, Fs14-24), and titanomagnetite (FeOt~63.75 wt% and TiO2~22.69 wt%). The whole-rock composition of these basalts has similar Mg# [mole Mg/mole(Mg+Fe2+)] (VT basalt:~0.56-0.58; VM basalt:~0.57), but differ in their total alkali content (VT basalt:~2.65; VM basalt:~3.24). The bulk composition of the magma was gradually depleted in MgO and enriched in FeOt, TiO2, P2O5, and Na2O with progressive fractionation, the basalts were gradually enriched in Y and Zr and depleted in Ni and Cr. In addition, the ΣREE of magma also increased with fractionation, without any change in the (La/ Yb)N value. Glass from the VM seamount shows more fractionated characters (Mg#: 0.56-0.57) compared to the outer ridge flank lava of the VT area (Mg#: 0.63-0.65). This study concludes that present basalts experienced low-pressure crystallization at a relatively shallow depth. The geochemical changes in the NCIR magmas resulted from fractional crystallization at a shallow depth. As a consequence, spinel was the first mineral to crystallize at a pressure >10 kbar, followed by Fe-rich olivine at <10 kbar pressure. | Dwijesh RAY Ranadip BANERJEE Sridhar D IYER Basavaraju BASAVALINGU Subir MUKHOPADHYAY4 | 2009 | Acta Geologica Sinica(English Edition)2009，83，6： | 2 |
| 4 | Effects of water and gas compositions on the internal corrosion of gas pipelines - modeling and experimental studies 显示文摘 | Sridhar N Dunn D S Anderko A M el at | 2001 | Corrosion2001，57，： | 1 |
| 5 | Spinal tubereulom in a patient with spinal myxopapiUary ependymoma 显示文摘 | Arora B Sridhar E Muzumdar D | 2010 | Cancer ResTher2010，6，2： | 1 |
| 6 | Pervaporation separation of isopropanol/water mixtures through crosslinked chitosan membranes显示文摘 | Devi D A Smitha B Sridhar S | 2005 | J Membr Sci2005，262，： | 1 |
| 7 | Break Temperatures of Mould Fluxes and Their Relevance to Continuous Casting显示文摘 | Sridhar S Mills K C Afrange O D C | 2000 | Ironmaking Steelmaking2000，27，3： | 1 |
| 8 | Repolariza- tion abnormalities and afterdepolarizations in a canine model of sudden cardiac death显示文摘 | SRIDHAR A NISHIJIMA Y TERENTYEV D : | 2008 | Am J Physiol Regul Integr Comp Physi- el2008，295，： | 1 |
| 9 | Separation of organic-or- ganic mixtures by pervaporation - a review 显示文摘 | Smitha B Suhanya D Sridhar S | | Journal of Mem- brane Science0，241，1： | 1 |
| 10 | Peripheral vascular complications after intracoronary stent placement: prevention by use of a pneumatic compression device 显示文摘 | Sridhar K Fischman D Goldberg S | 1996 | Cathet Cardiovasc Diagn1996，9，： | 1 |
| 11 | Bound rubber in chlorobutyl compounds:Influence of filler type and storage time 显示文摘 | Sridhar V Gupta B R Tripathy D K | 2006 | Journal of Applied Polymer Science2006，102，1： | 1 |
| 12 | Separation of organic-organic mixtures by pervaporation-a review显示文摘 | Smitha B Suhanya D Sridhar S | | 0，，01： | 1 |
| 13 | Effects of water and gas compositions on the internal corrosion of gas pipelines - modeling and experimental studies 显示文摘 | Sridhar N Dunn D S Anderko A M | 2001 | Corrosion2001，57，： | 1 |
| 14 | Optimal strategies for free-flight air traffic conflict resolution显示文摘 | Menon P K Sweriduk G D Sridhar B | 1999 | AIAA Journal of Guidance Control and Dynamics1999，22，2： | 1 |
| 15 | Microstructural stability of stressed lamellar and fiber composites显示文摘 | Sridhar N Rickman J M Srolovitz D J | 1997 | Acta Materialia1997，45，7： | 1 |
| 16 | 查看详情显示文摘 | Kumaraswamy G Rambabu D Jayaprakash N Venkata Rao G Sridhar B | | 0，，： | 1 |
| 17 | Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells显示文摘 | Suttner D M Sridhar K Lee C S | 1999 | Am J Physiol1999，276，： | 1 |
| 18 | Separation of organic- organic mixtures by pervaporation - a review显示文摘 | Smitha B Suhanya D Sridhar S | 2004 | J MembrSci2004，241，1： | 1 |
| 19 | Structure and function of BamE within the outer membrane and the β-barrel assembly machine显示文摘 | Knowles TJ Browning DF Jeeves M Maderbocus R Rajesh S Sridhar P Manoli E Emery D Sommer U Spencer A | | 0，，02： | 1 |
| 20 | Proton-conducting composite membranes of chitosan and sulfonated polysulfone for fuel cell application显示文摘 | Smitha B Devi D A Sridhar S | 2008 | International Journal of Hydrogen Energy2008，33，15： | 1 |
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