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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | 脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件显示文摘临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动。 | 刘莉 叶鹏 Alshehry ZH Mundra PA Barlow CK Mellett NA Wong G McConville MJ Simes J Tonkin AM Sullivan DR Barnes EH Nestel PJ Kingwell BA Marre M Neal B Poulter NR Rodgers A Williams B Zoungas S Hillis GS Chalmers J Woodward M Meikle PJ | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 3 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 4 | A range of clinical phenotypes associated with mutations in CRX,a photoreceptor transcription-factor gene显示文摘 | Sullivan L S Mintz-Hittner H A | 1998 | Am J Hum Genet1998，63，： | 1 |
| 5 | Homocysteine is a risk factor for cerebral small vessel disease,acting via endothelial dysfunction 显示文摘 | Hassan A Hunt BJ O'Sullivan M | 2004 | Brain2004，127，1： | 1 |
| 6 | Donor age affects differentiation of rat ventral mesencephalic stem cells显示文摘 | O'Keeffe G W Sullivan A M | 2005 | Neurosci Lett2005，375，2： | 1 |
| 7 | Coincident inactiva- tion of 14 3 3sigma and pl6INK4a is an early event in vulval squamous neop|asia显示文摘 | Gasco M Sullivan A Repellin C | 2002 | Oncogene2002，21，： | 1 |
| 8 | Freeze-dried whole plasma: Evaluating sucrose,trehalose, sorbitol, mannitol and glyeine as stabilizers显示文摘 | Bakaltcheva I O'Sullivan A M Hmel P | 2007 | Thrombosis research2007，120，1： | 1 |
| 9 | TGF beta-1downregulates DMP-1 and DSPP in odontoblasts显示文摘 | Unterbrink A O'Sullivan M Chen S | 2002 | Connect Tissue Res2002，43，23： | 1 |
| 10 | Ecology of testate amoebae in a North Carolina pocosin and their potential use as environmental and paleoenvironmental indicators显示文摘 | Booth R K Sullivan M E Sousa V A | 2008 | Ecoscience2008，5，2： | 1 |
| 11 | Practical application of molecular genetic testing as an aid to the surgical pathologic diagnosis of sarcomas:a prospective study显示文摘 | Hill D A O'Sullivan M J Zhu X | 2002 | Am J Surg Pathol2002，26，： | 1 |
| 12 | Evolution of JAK-STAT pathway components: mechanisms and role in immune system development 显示文摘 | Liongue C O'Sullivan L A Trengove M C | 2012 | PLoS ONE2012，7，3： | 1 |
| 13 | Acute hypexernia stimulates ANP secretion in vivo显示文摘 | Raertscli A Adams J Sullivan M | 1998 | Am J Physiol1998，255，： | 1 |
| 14 | Influence of transglutaminase treatment on some physico-chemical properties of milk 显示文摘 | O' Sullivan M M Kelly A L Fox P F | 2002 | Dairy Research2002，69，： | 1 |
| 15 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 16 | Age-related decline in brain white matter anisotropy measured with spatially corrected echo- planar diffusion tensor imaging显示文摘 | Pfefferbaum A Sullivan EV Hedehus M | 2000 | Magnetic Resonance in Medicine2000，44，2： | 1 |
| 17 | Diagnostic gold standard for soft tissue tumour:morphology or molecular genetics显示文摘 | Pfeifer J D Hill D A O'Sullivan M J | 2000 | Histopathology2000，37，： | 1 |
| 18 | Agerelated decline in brain white matter anisotropy measured with spatially corrected echoplanar diffusion tensor imaging显示文摘 | Pfefferbaum A Sullivan E V Hedehus M | 2000 | Magn Reson Med2000，44，2： | 1 |
| 19 | Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene显示文摘 | Blezinger P Wang J Gondo M Quezada A Mehrens D French M Singhai A Sullivan S Rolland A Ralston R Min W | | 0，，： | 1 |
| 20 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
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