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| 1 | Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization显示文摘AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization.METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization. | Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul Kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya Richard Kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 2 | 强化与标准降压治疗对脑卒中亚型的影响显示文摘在收缩压干预试验(systolic blood pressure intervention trial, SPRINT)中,各治疗组的脑卒中发生比例差异无统计学意义,但脑卒中亚型的病因不同,可能对强化降压治疗的反应不同。SPRINT纳入患者(n=9 361)随机分为目标收缩压<120 mm Hg(1 mm Hg=0.133 kPa)的强化治疗与目标收缩压<140 mm Hg的标准治疗组。 | Wright CB Auchus AP Lerner A Ambrosius WT Ay H Bates JT Chen J Meschia JF Pancholi S Papademetriou V Rastogi A Sweeney M Willard JJ Yee J Oparil S 赵狄(摘译) 郑武洪(审校) | 2021 | 中华高血压杂志2021，29，3： | 2 |
| 3 | Blueberry flavonoids inhibit matrix metalloproteinase activity in DUI45 human prostate cancer cells显示文摘 | MATCHETF M D MACKINNON S L SWEENEY M L | 2005 | Biochem Cell Biol2005，83，： | 1 |
| 4 | Brucella abortus detection by PCR assay in blood,miLk and lymph tissue of serologically positive cows显示文摘 | O'Leary S Sheahan M Sweeney T | 2006 | Res Vet Sci2006，81，2： | 1 |
| 5 | Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells显示文摘 | Bao S Wang Y Sweeney P | 2005 | Am J Physiol Lung Cell Mol Physiol2005，288，1： | 1 |
| 6 | The effect of enclosure size on social interactions and daily activity patterns of the captive Asiatic wild horse (Equus przewalskii)显示文摘 | Hogan E S Houpt K A Sweeney K | 1988 | Applied Animal Behaviour Science1988，21，12： | 1 |
| 7 | Specific pathogenfree Penaeus vannamei 显示文摘 | Wyban J A Swingle J S Sweeney J N | 1995 | World Aquaculture1995，24，： | 1 |
| 8 | Fraudulent misstated financial statements and insider trading: an empirical analysis 显示文摘 | Summers S L Sweeney J T | 1998 | The Accounting Review1998，73，1： | 1 |
| 9 | Matrix elasticity directs stem cell lineage specification显示文摘 | Engler AJ Sen S Sweeney HL | 2006 | Cell2006，126，4： | 1 |
| 10 | Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer显示文摘 | Sweeney C Coles BF Nowell S Lang NP Kadlubar FF | 2002 | Toxicology2002，18，： | 1 |
| 11 | The expression o{ p- selectin during collection, processing and storage of platelet concentrates: relationship to loss of in vivo viability 显示文摘 | Holme S Sweeney JD Sawyer S | 1997 | Transfusion1997，37，1： | 1 |
| 12 | The effects of lactose inclusion and seaweed extract on performance, nutrient digestibility and microbial populations in newly weaned piglets 显示文摘 | Dillon S Sweeney T Figat S | 2010 | Livestock Science2010，134，： | 1 |
| 13 | Addtion of L-carnitine to additive solution-suspended red cell stored at 40C reduces in vitrohemolysis and improves in vivo viability显示文摘 | Arduine A Holme S Sweeney JD | | 0，，： | 1 |
| 14 | The use of ensemble empirical mode decomposition with ca- nonical correlation analysis as a novel artifact removal technique显示文摘 | SWEENEY K T MCLOONE S F WARD T E | 2013 | IEEE Transactions on Biomedical Engi- neering2013，60，1： | 1 |
| 15 | Matrix elasticity directs stem cell lineage specification显示文摘 | Engler AJ Sen S Sweeney HL | 2006 | Cell2006，126，4： | 1 |
| 16 | Notch and vascular smooth muscle cell phenotype 显示文摘 | MORROW D GUHA S SWEENEY C | 2008 | Circ Res2008，103，12： | 1 |
| 17 | Depicting Women as Sex Objects in Television Advertising: Effects on Body Dissat isfaction 显示文摘 | Lavine H Sweeney D Wagner S H | 1999 | Social Psychology1999，25，： | 1 |
| 18 | Study on the flow structure in an aerated flat apparatus using laser Doppler anemometry显示文摘 | Becker S De Bie H Sweeney J | 2000 | Chemical Engineering and Technology2000，23，3： | 1 |
| 19 | Matrix elasticity directs stem cell lineage specification 显示文摘 | ENGLER A SEN S SWEENEY H L | 2006 | Cell2006，126，4： | 1 |
| 20 | Antiviralgene expression in rheumatoid arthritis : role ofIKKepsilon and interferon regulatory factor 3 显示文摘 | SWEENEY S E MO L FIRESTEIN G S | 2007 | Arthritis Rheum2007，56，3： | 1 |
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