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1Involvement of serum retinoids and Leiden mutation in patients with esophageal, gastric, liver, pancreatic, and colorectal cancers in Hungary显示文摘AIM: To analyze the serum levels of retinoids and Leiden mutation in patients with esophageal, gastric, liver,pancreatic, and colorectal cancers.METHODS: The changes in serum levels of retinoids (vitamin A, α- and β-carotene, α- and β-cryptoxanthin,zeaxanthin, lutein) and Leiden mutation were measured by high liquid performance chromatography (HPLC)and polymerase chain reaction (PCR) in 107 patients (70 males/37 females) with esophageal (0/8), gastric (16/5), liver (8/7), pancreatic (6/4), and colorectal (30/21including 9 patients suffering from in situ colon cancer)cancer. Fifty-seven healthy subjects (in matched groups)for controls of serum retinoids and 600 healthy blood donors for Leiden mutation were used.RESULTS: The serum levels of vitamin A and zeaxanthin were decreased significantly in all groups of patients with gastrointestinal (GI) tumors except for vitamin A in patients with pancreatic cancer. No changes were obtained in the serum levels of α- and β-carotene,α- and β-cryptoxanthin, zeaxanthin, lutein in patients with GI cancer. The prevalence of Leiden mutation significantly increased in all groups of patients with GI cancer.CONCLUSION: Retinoids (as environmental factors)are decreased significantly with increased prevalence of Leiden mutation (as a genetic factor) in patients before the clinical manifestation of histologically different (planocellular and hepatocellular carcinoma, and adenocarcinoma) GI cancer.Gyula Mózsik Gy(o|¨)rgy Rumi András D(o|¨)m(o|¨)t(o|¨)r Mária Figler Beáta Gasztonyi El(?)d Papp Alajos Pár Gabriella Pár József Belágyi Zoltán Matus Béla Melegh 2005World Journal of Gastroenterology2005,11,48:2
2Volu nt a r y Di s clo s u r e i n a n Eme r g i n g Ca pit a lMarket:Some Empirical Evidence from CompaniesListed on the Kuala Lumpur Stock Exchange显示文摘H o s s a i n M L M Ta n M B A d a m s 1994TheInternational Journal of Accounting1994,29,4:1
3A segmentation algorithm for the automatic recognition of Fuji Apples atharvest 显示文摘Bulanon D M Kataoka T O ta Y 2002Biosystems Engineering2002,83,4:1
4M ethodologyfor vertical-navigation flight-trajectory cost calculationusing a perform ance d atabase显示文摘M U R R IE TA M E N D O ZA A B O TEZ R M 2015Journal ofA erospace Inform ation System s2015,12,51:1
5Atypical subtrochanteric and diaphyseal femoral fractures:Second report of a task force of the American Society for Bone and Mineral Research显示文摘Shane E Burr D Abrahamsen B Adler RA Brown TD Cheung AM Cosman F Curtis JR Dell R Dempster DW Ebeling PR Einhorn TA Genant HK Geusens P Klaushofer K Lane JM McKiernan F McKinney R Ng A Nieves J O'Keefe R Papapoulos S Howe TS van der Meulen MC Weinstein RS 0,,:1
6Biodegradability of slatwohterhouse wastewater with high blood content under anaerobic and aerobic conditions 显示文摘Pozo R del Ta D O Dulkadiro lu H 2003J Chem Technol Biotechnol2003,78,4:1
7Results of a pilot study on theeffects of propofol a n d d e x m e d e t o m i d i n e on inflammatory responses a ndintraabdominal pressure in severe sepsis 显示文摘Ta s d o g a n M M e m i s D Sut N J Clin A n e s t h0,21,6:1
8Optical detection of brain tumors using quantum dots 显示文摘Steven TA Hamid D Muhammad O 2005Nanosensing: Mate Dev Ⅱ2005,6009,:1
9A new alumina-supported,not pyrophoric Raney-type Ni-catalyst显示文摘PETR(O) J B(O)TA A L(A)SZL(O) K BEYER H K(A)LM(A)N E D(O)DONY I 0,,1:1
10Bright spatially coherent synchrotron X-rays from a table-top source显示文摘Kneip S Mcguffey C Martins J L Martins S F Bellei C Chvykov V Dollar F Fonseca R Huntington C Kalintchenko G Maksimchuk A Mangles S P D Matsuoka T Nagel S R Palmer C A J Schreiber J Phuoc K Ta Thomas A G R Yanovsky V Silva L O Krusheln 2010Nature Physics2010,,12:1
11Monoclonal anti- body therapy of T cell lymphoma: single agent trials of anti-CD2 (Siplizumab) and anti-CD4 ( Humax-CD4 ) 显示文摘Janik JE O' Mahony D Waldmann TA 2009Hematology Meeting Reports2009,3,1:1
12Compr ehensive ove r v iew of nu r si ng a ndinterdisciplinary care of the acute ischemic strokepatient:a scientific statement from the American HeartAssociation显示文摘Summe r s D L e o n a r d A We n two r t h D e ta l 2009Stroke2009,40,:1
13Mutations in OTOGL,encoding the in-ner ear protein otogelin-like,cause moderate sensorineural hear-ing loss显示文摘Yariz KO Duman D Seco CZ Dallman J Huang M Peters TA Sirmaci A Lu N Schraders M Skromne I Oostrik J Di-az-Horta O Young JI Tokgoz-Yilmaz S Konukseven O Shahin H Hetterschijt L Kanaan M Oonk AM Edwards YJ Li H Ata-lay S Blanton S Desmidt AA Liu XZ Pennings 0,,:1
14Migraine and tension headache: a meta-analytic review显示文摘Blanchard EB Andrassik F Ahles TA Teders ST O'Keefe D 1980Behav Ther1980,11,5:1
15Phase Ⅰ trial of a selective c-MET inhibitor ARQ 197 incorporating proof of mechanism pharmacodynamic studies显示文摘Yap TA Olmos D Brunett O 0,,10:1
16Bright spatially coherent synchrotron X-rays from a table-top source显示文摘Kneip S Mcguffey C Martins J L Martins S F Bellei C Chvykov V Dollar F Fonseca R Huntington C Kalintchenko G Maksimchuk A Mangles S P D Matsuoka T Nagel S R Palmer C A J Schreiber J Phuoc K Ta Thomas A G R Yanovsky V Silva L O Krusheln 2010Nature Physics2010,,12:1
17Lipase - catalysed production of biodiesel fuel from some Nigerian lauric oils显示文摘ABIGOR R D UADIA P O FOGLIA TA 2000Biochem Soc Trans2000,28,6:1
18Insecticidal toxins from the bacterium Photorhabdus luminescens显示文摘Bowen D Rocheleau TA Blackburn M Andreev O Golubeva E Bhartia R ffrench-Constant RH 0,,5372:1
19Playing dirtyor building capability- corruption and HR training as competitiveactions to threats from informal and foreign firmrivals显示文摘IRIYAMA A K ISH O RE R TA LU K D A R D 2006Strategic Management Journal2006,,10:1
20A segmentation algorithm for the automatic recognition of Fuji Apples at harvest显示文摘Bulanon D M Kataoka T O ta Y 2002Biosystems Engineering2002,83,4:1
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