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| 1 | 代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。 | 周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M | 2020 | 中华高血压杂志2020，28，9： | 7 |
| 2 | Nitrite-derived nitric oxide by xanthine oxidoreductase protects the liver against ischemia- reperfusion injury显示文摘It was demonstrated that xanthine oxidoreductase (XOR), during ischemia, catalyzes the formation of nitric oxide (NO) from nitrite (NO2-) and this NO2--derived NO protects the isolated perfused rat heart against the damaging effects of ischemia-reperfusion (I/R) when conventional nitric oxide synthase (NOS) -dependent NO production is impaired. Liver is one of the organs with the highest XOR concentration. This study was designed to determine whether NO2--derived NO by XOR protects liver against I/R injury in vivo. For its minute amounts and active reactivity, NO can not be detected directly in real time in vivo by this time. We have to prove the above hypothesis indirectly. METHODS:Wistar rats were pretreated with saline, NOS inhibitor L-NAME (10 mg/kg intravenously), XOR inhibitor allopurinol (1.5 mg/kg orally), L-NAME +allopurinol and NO scavenger carboxy-PTIO (0.6 mg/kg intravenously) respectively (12 animals per group). And then, they were subjected to total liver ischemia for 40 minutes followed by reperfusion. Blood samples and liver tissues were obtained for analysis after 3 hours of reperfusion. Survival was also investigated. RESULTS:Allopurinol-treated animals exhibited further increased serum alanine aminotransferase (ALT) levels and liver myeloperoxidase (MPO) activities, but further decreased liver adenosine triphosphate (ATP) stores after I/R compared to saline-treated counterparts (830.5±108.3 U/L, 56.5±11.0 U/mg protein and 1.93±0.47 μmol/g vs. 505.8± 184.2 U/L, 41.5±10.2 U/mg protein and 3.05±0.55 μmol/g respectively, P<0.01, P<0.05 and P<0.01 respectively). The hepatocyte injury was further exacerbated and the overall survival rate was significantly decreased after I/R in animals given by allopurinol compared to those pretreated by saline (P<0.05). L-NAME and allopurinol co-treated animals exhibited more severe liver injury (P<0.05 and P<0.01) and a further decreased overall survival rate (P<0.05) compared to L-NAME or allopurinol alone-treated counterparts, but they were not different from carboxy-PTIO treated animals (P>0.05). CONCLUSION:NO2--derived NO by XOR in the hypoxic and acidic environment induced by hepatic I/R protects the liver against I/R injury in vivo. | Department of General Surgery ( Lu P, Wang CY and Chen DD), and Department of Radiology (Liu F), Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China Cold Spring Harbor Laboratory, New York 11724, USA ( Yao Z) General Surgery Laboratory, Union Hospital, Tongji Medical College , Huazhong University of Science and Technology, Wuhan 430022 , China (Tian Y, Zhang JH and Wu YH) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 4 |
| 3 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 4 | FOUR NEW GLYCOSIDES, LIGUROBUSTOSIDES A, B, C AND D FROM LIGUSTRUM ROBUSTUM显示文摘FOURNEWGLYCOSIDES,LIGUROBUSTOSIDESA,B,CANDDFROMLIGUSTRUMROBUSTUM￥JunTIAN;HongJieZHANGandHanDongSUN.(Laboratoryofphytochemistr... | Tian, J Zhang, HJ Sun, HD Pan, LT Yao, P Chen, DY | 1996 | Chinese Chemical Letters1996，7，4： | 3 |
| 5 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013，23，9： | 3 |
| 6 | Direct and indirect effects of solar variations on stratospheric ozone and temperature显示文摘We have used a fully coupled chemistry-climate model(WACCM)to investigate the relative importance of the direct and indirect effects of 11a solar variations on stratospheric temperature and ozone.Although the model does not contain a quasi-biennial oscillation(QBO)and uses fixed sea surface temperature(SST),it is able to produce a second maximum solar response in tropical lower stratospheric(TLS)temperature and ozone of approximately 0.5 K and 3%,respectively.In the TLS,the solar spectral variations in the chemistry scheme play a more important role than solar spectral variations in the radiation scheme in generating temperature and ozone responses.The chemistry effect of solar variations causes significant changes in the Brewer-Dobson(BD)circulation resulting in ozone anomalies in the TLS.The model simulations also show a negative feedback in the upper stratosphere between the temperature and ozone responses.A wavelet analysis of the modeled ozone and temperature time series reveals that the maximum solar responses in ozone and temperature caused by both chemical and radiative effects occur at different altitudes in the upper stratosphere.The analysis also confirms that both the direct radiative and indirect ozone feedback effects are important in generating a solar response in the upper stratospheric temperatures,although the solar spectral variations in the chemistry scheme give the largest solar cycle power in the upper stratospheric temperature. | SHANG Lin TIAN WenShou DHOMSE Sandip CHIPPERFIELD Martyn P LIU Yi WANG WuKe | 2013 | Chinese Science Bulletin2013，58，31： | 2 |
| 7 | Multifrequency large amplitude pulse voltammetry: A novel electrochemical method for electronic tongue显示文摘 | Tian S Y Deng S P Chen Z X | 2007 | Sensor and Actuator B: Chem2007，123，2： | 1 |
| 8 | 显示文摘 | Hu Z J Yang J X Tian Y P | 2007 | Bull Chem Soc Jpn2007，80，5： | 1 |
| 9 | A surver on delayed feedback control of chaos 显示文摘 | Tian Y P Zhu J D Chen G R | 2005 | Journal of Control Theory and Application2005，3，4： | 1 |
| 10 | Image enhancement and minutiae matching in fingerprint verification显示文摘 | He Y L Tian J Luo X P | 2003 | Pattem Recognition Letters2003，24，910： | 1 |
| 11 | The protecting effects and mechanisms of baicalin and octreotide on heart injury in rats withSAP显示文摘 | Zhang X P Tian H Chen H Q etal | 2007 | Mediators of Inflamm2007，2007，19： | 1 |
| 12 | Capillary electrophoresis microchips with thick-film amperometric detectors: separation and detection of phenolic compounds 显示文摘 | Wang J Chatrathi M P Tian B | 2000 | Analytica Chemica Acta2000，416，： | 1 |
| 13 | A novel conflict reassignment method based on grey relational analysis (GRA)显示文摘 | Xu G P Tian W F Qian L | 2007 | Pattern Recognition Letters2007，28，15： | 1 |
| 14 | Comb-dendritic block copolymers as tree-shaped macromolecular amphiphiles for nanoparticle self assembly显示文摘 | Tian L Hammond P T | 2006 | Chem Mater2006，18，： | 1 |
| 15 | Robot-assisted laparoscope fundoplication for gastroesophageal reflux disease:A systematic review of randomized controlled trials显示文摘 | Zhang P Tian JH Yang KJ | 2010 | Digestion2010，81，1： | 1 |
| 16 | Volatile composition of Chinese Hippophae rhamnoides and its chemotaxonomic implications 显示文摘 | Tian C J Nan P Chen J K | 2004 | Biochem Syst Ecol2004，32，： | 1 |
| 17 | Evaluation of the use of high CO2concentrations and cold storage to control Monilinia fructicola on sweet cherries显示文摘 | Tian S P Fan Q Xu Y | 2001 | Postharvest Biology and Technology2001，22，1： | 1 |
| 18 | Partial discharge detection in cable using VHF capacitive couplers显示文摘 | Tian Y Lewin P L Davies A E | 2003 | IEEE Trans on Dielectrics and Electrical Insulation2003，10，2： | 1 |
| 19 | Effect of temperature during co-nidial formation of Monilinia laxa on conidial size,ger-mination and infection of stored nectarines显示文摘 | Tian S P Bertolini P | 1999 | Journalof Phytopathology1999，147，： | 1 |
| 20 | Application of the simulated annealing algorithm to the combinatorial optimization problem with permutation property:an investigation of generation mechanism显示文摘 | TIAN P MA J ZHANG D M | | 0，，01： | 1 |
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