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33篇 您的检索式:作者名="Tuo Liang"
    题名 作者 年代 出处 被引量
1Characteristics of and strategies for patients with severe burn-blast combined injury显示文摘背景严重灼伤强风联合了损害是对为它的高死亡的医疗队的大挑战。这研究的目的是阐明损害并且到现在的临床的特征我们有严重灼伤强风的五个病人联合了的如此的 cases.Methods 的治疗上的临床的经验损害进入我们在 2005 年 6 月 7 日 77 个小时损害以后的医院。灼伤程度从 80% ~ 97%(89.6% 鞪? 亘吗??CHAI Jia-ke SHENG Zhi-yong LU Jiang-yang WEN Zhong-guang YANG Hong-ming JIA Xiao-ming LI Li-gen CAO Wei-hong HAO Dai-feng SHEN Chuan-an TUO Xiao-ye LIANG Li-ming WANG Shu-jun 2007Chinese Medical Journal2007,,20:17
2Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event.TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou 2018Science China(Physics,Mechanics & Astronomy)2018,61,3:12
3Effect of total dissolved gas supersaturated water on early life of David's schizothoracin (Schizothorax davidi)显示文摘The effect of total dissolved gas (TDG) supersaturation on fish living downstream of dams is one of the main ecological risks of high dam construction. A strategy for mitigating the negative effects is needed urgently since many high dams are under construction in the upper reaches of the Yangtze River in China. Experiments on the hatching process of David's schizothoracin were carried out and the results show that the hatching rate decreased with increasing TDG levels, and that most eggs hatched within a very short time in the higher TDG saturation groups. By using a stereomicroscope, damages to the head, yolk sac, body, anus, etc. were found in larvae which hatched in TDG supersaturated water. Results show that the lesion rate increased with increasing TDG levels. Furthermore, 7-d-old David's schizothoracin were exposed to TDG supersaturated water levels of 100%, 105%, 110%, 115%, 120%, 125%, 130%, 135%, and 140% for testing their tolerance to TDG supersaturation. We found that the median lethal concentrations (LC50 ) for 13, 14, 20, 35, 52, 73, and 96 h exposure were 138%, 138%, 134%, 130%, 129%, 128%, and 126%, respectively. The median lethal times (LT50 ) were 7.49, 11.04, 19.25, and 35.38 h for exposure to water with TDG levels of 145%, 140%, 135%, and 130%, respectively.Rui-feng LIANG Bo LI Ke-feng LI You-cai TUO 2013Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013,14,7:6
4Effects of Salinity on Embryonic Development, Survival, and Growth of Crassostrea hongkongensis显示文摘This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artificial seawater at three different salinities(low, 15; medium, 23; and high, 30) to determine the optimum hatchery and nursery conditions for mass production of the seeds. Results showed that the percentage production of straight-hinged larvae from fertilized eggs was significantly lower at the high salinity than at the low- and medium-salinities(P < 0.05). The survival rates of larvae and juveniles differed significantly among the three salinity trials, with the highest survival rate observed at the low salinity(P < 0.05). The shell height of larvae was significantly larger at the low salinity than at the high and medium salinities from days 9 to 15(P < 0.05), whereas that of juveniles was significantly larger at the low salinity than at the high and medium salinities on day 70(P < 0.05). These results indicate that the larvae and juveniles of C. hongkongensis are tolerant to a wide range of salinities(15 to 30), but show better growth and survival at relatively low salinities. Thus, it is recommended to use relatively low salinities in hatchery and nursery systems for improved yields of C. hongkongensis.HUO Zhongming WANG Zhaoping LIANG Jian ZHANG Yuehuan SHEN Jianping YAO Tuo SU Jiaqi YU Ruihai 2014Journal of Ocean University of China2014,13,4:6
5Three Cases of COVID-19 Variant Delta With and Without Vaccination——Chengdu City,Sichuan Province,April-May,2021显示文摘On April 26,2021,a 33-year-old male Chinese sailor returning from India via Kathmandu,Nepal,tested positive for the coronavirus disease 2019(COVID-19)by Chengdu Customs and was confirmed positive by Chengdu CDC(Case A).On May 2,2021,a housewife in the same flight tested positive for COVID-19 by Pengzhou CDC in Sichuan Province during her quarantine period and was confirmed positive by Chengdu CDC the next day(Case B).Heng Chen Yi Mao Zhenhua Duan Liang Wang Yue Cheng Yingxue Dai Haixia Luo Wenjun Xie Shuangfeng Fan Yuzhen Zhou Jingpei Xu Lan Feng Liwen Hu Zhu Liu Xian Liang Liangshuang Jiang Xiaoli Tuo 2021China CDC weekly2021,3,25:5
6Study on purification and ultrastructure of a baculovirus in Penaeus chinensis显示文摘Shi Tuo, Kong Jie, Bao Zhenmin, Liu Ping and Wang Chongming (Huanghai Sea Fisheries Research Institute, Qingdao 266071, China)Liang Xingming, (College of Marine Life Sciences, Ocean University of Qingdao, Qingdao 266003, China) 1998Acta Oceanologica Sinica1998,17,4:4
7The effect of pmpR on the type Ⅲ secretion system in Pseudomonas aeruginosa显示文摘The type III secretion system(T3SS) plays important roles in Pseudomonas aeruginosa pathogenicity.Previously,we reported that the uncharacterized protein PmpR could regulate pqsR,an important regulator in the quorum-sensing system,by directly binding to its promoter region.As the T3SS is controlled by the quorum-sensing system,here,we investigated the relationship between PmpR and the T3SS.Our data showed that expression of the T3SS genes exoS,exoY,exoT,and exsD was dramatically increased in a pmpR-deletion mutant compared with that in the wild-type P.aeruginosa strain PAO1.Data from DNA mobility assays indicated that PmpR affects the T3SS indirectly.It is unlikely that PmpR controls the T3SS via the Pseudomonas quinolone signal(PQS) because the PQS negatively regulates the T3SS,while pmpR negatively regulates the PQS.The effect of PmpR on the T3SS seems to be independent of the PQS;further investigation is required to uncover the underlying regulatory pathways.LIANG HaiHua KONG WeiNa SHEN Tuo DUAN JiaLi DUAN KangMin 2012Chinese Science Bulletin2012,57,19:4
8Effect of Daxx on cholesterol accumulation in hepatic cells显示文摘AIM:To study the effect of Daxx on cholesterol accumulation in hepatic cells. METHODS: Sprague Dawley (SD) rats were fed a normal or high fat diet for 6 wk, and serum lipids and Daxx expression of hepatic tissues were measured by immunoblot assays. HepG2 cells were transfected with the pEGFP-C1/Daxx or pEGFP-C1 plasmid. Cells stably transfected with Daxx were identified by RT- PCR analysis. Total cholesterol levels were determined by high performance liquid chromatography. Activated- SREBP and caveolin-1 were assayed by western blotting. RESULTS: Hepatic Daxx protein was higher in normal rats than in high fat diet-fed rats. Noticeable negative correlations were seen between Daxx and LDL-C (γ = -7.56, P = 0.018), and between Daxx and TC (γ = -9.07, P = 0.01), respectively. The total cholesterol of HepG2/GFP-Daxx cells was lower than that of control cells or HepG2/GFP cells (9.28 ± 0.19 vs 14.36 ± 4.45 or 13.94 ± 2.62, both P < 0.05). Furthermore, in HepG2/GFP cells, the expression of activated SREBP was lower than that of control cells, whereas caveolin-1 expression was higher. CONCLUSION: Overexpression of Daxx in HepG2 cells decreased intracellular cholesterol accumulation, which might be associated with inhibition of SREBP activity and an increase in caveolin-1 expression.Qin-Hui Tuo Lei Liang Bing-Yang Zhu Xuan Cao Duan-Fang Liao 2008World Journal of Gastroenterology2008,14,3:3
9Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang 2020Science China(Physics,Mechanics & Astronomy)2020,63,4:2
10Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq显示文摘Phosphoenolpyruvate carboxykinase 1(PCK1),a step limiting enzyme of gluconeogenesis,is downregulated in hepatocellular carcinoma(HCC).Overexpression of PCK1 has been shown to suppress hepatoma cell growth,but the underlying mechanism remains unclear.We used recombinant adenovirus overexpressing PCK1 or GFP in Huh7 cells,and the differentially expressed genes(DEGs)were identified by RNA-Seq.180 were upregulated by PCK1 overexpression,whereas 316 were downregulated.Pathway analysis illustrated that PCK1 was closely correlated with Wnt signaling pathway and TGF-beta signaling pathway.Hence,Wnt signaling pathway and its downstream component,FZD2,FZD6,FZD7 and b-catenin were confirmed by qRT-PCR and Western blot.In vivo we also observed that PCK1 had restrained tumor growth as a result of decreasing expression of b-catenin.Whole-transcriptomic profile analysis discovered that overexpression of PCK1 downregulates several oncogenic signaling pathways in HCC,providing potential therapeutic targets for improving HCC therapy.Jin Xiang Yuhong Zhang Lin Tuo Rui Liu Dongmei Gou Li Liang Chang Chen Jie Xia Ni Tang Kai Wang 2020Genes & Diseases2020,7,1:2
11Geochemistry, Sr-Nd-Pb Isotopic Compositions and Zircon U-Pb Geochronology of Neoproterozoic Mafic Dyke in the Douling Complex, South Qinling Belt, China显示文摘Mafic dyke swarm is widely developed in Proterozoic continental lithosphere.The Gangou diabase dyke from the Xixia area,intruded into the Douling complex of the South Qinling belt,yields zircon UPb age of 731 Ma.It has low SiO2 content(49.02 wt.%-49.37 wt.%)and Mg^#(34.0–37.7)and shows characteristics of subalkaline tholeiite series.They show highΣREE(155.5×10^-6–184.7×10^-6),weak negative Eu anomaly(δEu=0.88-0.93),slight depletion of Nb and Ta,and enrichment of LILE.Their major and trace element,Sr-Nd-Pb isotope and clinopyroxene compositions indicate that it originated from the partial melting of the asthenospheric mantle within-plate extension setting and was slightly contaminated by crust compositions.The similarities of formation age,petrogenesis,source characteristic and tectonic setting for Gangou diabase with mafic dykes in Wudang Block and mafic volcanic rocks in Yaolinghe Group indicate that the South Qinling belt underwent strong continental extension in Neoproterozoic during 796–685 Ma most likely correspondence to the breaking-up of the Rodinia supercontinent.Tong Li Liang Liu Xiao-Ying Liao Yong-Sheng Gai Tuo Ma Chao Wang 2020Journal of Earth Science2020,31,2:2
12Terahertz radiation of a butterfly-shaped photoconductive antenna(invited)显示文摘The terahertz(THz) far-field radiation properties of a butterfly-shaped photoconductive antenna(PCA) were experimentally studied using a home-built THz time-domain spectroscopy(THz-TDS) setup.To distinguish the contribution of in-gap photocurrent and antenna structure to far-field radiation,polarization-dependent THz field was measured and quantified as the illuminating laser beam moved along the bias field within the gap region of electrodes. The result suggests that, although the far-field THz radiation originates from the in-gap photocurrent, the antenna structure of butterfly-shaped PCA dominates the overall THz radiation. In addition, to explore the impact of photoconductive material,radiation properties of butterfly-shaped PCAs fabricated on both low-temperature-grown GaAs(LT-GaAs) and semi-insulating GaAs(Si-GaAs) were characterized and compared. Consistent with previous experiments, it is observed that while Si-GaAs-based PCA can emit higher THz field than LT-GaAs-based PCA at low laser power, it would saturate more severely as laser power increased and eventually be surpassed by LT-GaAs-based PCA. Beyond that, it is found the severe saturation effect of Si-GaAs was due to the longer carrier lifetime and higher carrier mobility, which was confirmed by the numerical simulation.Jitao Zhang Mingguang Tuo Min Liang Wei-Ren Ng Michael E.Gehm Hao Xin 2019红外与激光工程2019,48,4:1
13Measurement of^(134)Xe(n,2n)^(133m),gXe reaction cross sections in 14‑MeV region with detailed uncertainty quantification显示文摘A lead-shielded HPGe detector and offlineγ-ray spectra of the residual product were used to measure the cross section(CS)and ratios of isomeric CS(σm/σg)in^(134)Xe(n,2n)^(133m),gXe reactions at different energies(13.5 MeV,13.8 MeV,14.1 MeV,14.4 MeV,14.8 MeV)relative to the^(93)Nb(n,2n)^(92)mNb reaction CS.The target was high-purity natural Xe gas under high pressure.The T(d,n)4He reaction produces neutrons.TALYS code(version 1.95)for nuclear reactions was used for calculations,with default parameters and nuclear level density models.The uncertainties in the measured CS data were thoroughly analyzed using the covariance analysis method.The results were compared with theoretical values,evaluation data,and previous experimental findings.CS data of the 134Xe(n,2n)133mXe and 134Xe(n,2n)133gXe reactions and the corresponding isomeric CS ratios at 13.5 MeV,13.8 MeV,and 14.1 MeV neutron energies are reported for the first time.This research advances our knowledge of pre-equilibrium emission in the(n,2n)reaction channel by resolving inconsistencies in the Xe data.Jun‑Hua Luo Jun‑Cheng Liang Li Jiang Fei Tuo Liang Zhou Long He 2023Nuclear Science and Techniques2023,34,1:1
14Interest filter vs interest operator: face recognition using Fisher linear diseriminant based on interest filter representation 显示文摘Zhao Tuo Liang Zhizheng ZHANG D 2008Pattern Recognition Letlers2008,,29:1
15Influence of total dissolved gas-supersaturated water on silver carp(Hypophthalmichthys molitrix)显示文摘Dam discharges over spillways are the main reason for the gas-supersaturated water generated in rivers.Local aquatic organisms,especially fish,readily develop gas bubble disease(GBD) in a river with total dissolved gas supersaturation(TDGS).Sometimes,fish will die after a specific exposure period,which negatively affects the biological equilibrium.In this study,the influence of TDGS on silver carp was explored.Silver carp were exposed to gas-supersaturated water with TDGS levels of 140%,135%,130%,125%,120%,and 110%to test the impact of TDGS.Some silver carp died when the TDGS level was 120%or higher,and all the silver carp exposed to a TDGS level of 140%died within10 h.In comparison with the Chinese sucker,Prenant's schizothoracin,and rock carp,silver carp seem less sensitive to TDGS.In addition,we tested the catalase(CAT) activity in the muscles and gills of silver carp after they were exposed to gas-supersaturated water with a TDGS level of140%.The CAT activity changed with time;it increased first and then decreased until it was lower than the initial CAT activity.The results of this study can provide basic data for developing a standard for environmental evaluation.Lu Cao Rui-feng Liang You-cai Tuo Yong Li Ke-feng Li 2016Water Science and Engineering2016,9,4:1
16Projected gradient method for kernel discriminant nonnegative matrix factorization and the applications显示文摘Liang Zhizheng Li Youfu Zhao Tuo 2010Signal Processing2010,90,7:1
17Role of the Hedgehog pathway in hepatocellular carcinoma (Review)显示文摘Xin Zheng Wen Zeng Xiaohong Gai Qiuran Xu Chao Li Zheyong Liang Hang Tuo Qingguang Liu 2013Oncology Reports2013,,5:1
18Projected gradient method for kernel diacriminant nonnegative matrix factorization and the applications显示文摘LIANG ZHLZHENG Ll YOUFU ZHAO TUO 0,,07:1
19A novel ambigrammatic mycovirus,PsV5,works hand in glove with wheat stripe rust fungus to facilitate infection显示文摘Here we describe a novel narnavirus,Puccinia striiformis virus 5(PsV5),from the devastating wheat stripe rust fungus P.striiformis f.sp.tritici(Pst).The genome of PsV5 contains two predicted open reading frames(ORFs)that largely overlap on reverse strands:an RNA-dependent RNA polymerase(RdRp)and a reverseframe ORF(rORF)with unknown function.Protein translations of both ORFs were demonstrated by immune technology.Transgenic wheat lines overexpressing PsV5(RdRp-rORF),RdRp ORF,or rORF were more susceptible to Pst infection,whereas PsV5-RNA interference(RNAi)lines were more resistant.Overexpression of PsV5(RdRp-rORF),RdRp ORF,or rORF in Fusarium graminearum also boosted fungal virulence.We thus report a novel ambigrammatic mycovirus that promotes the virulence of its fungal host.The results are a significant addition to our understanding of virosphere diversity and offer insights for sustainable wheat rust disease control.Yanhui Zhang Xiaofei Liang Mengxin Zhao Tuo Qi Hualong Guo Jing Zhao Jie Zhao Gangming Zhan Zhensheng Kang Li Zheng 2023Plant Communications2023,4,3:1
20Conformally Mapped Multifunctional Acoustic Metamaterial Lens for Spectral Sound Guiding and Talbot Effect显示文摘We demonstrate a conformally mapped multifunctional acoustic metamaterial Mikaelian lens.Mikaelian lens is a gradient medium with a hyperbolic secant refractive index profile that can realize functions like beam self-focusing.Unlike the conventional design approaches,with a conformal transformation method,only isotropic material parameters with gradient refractive index profiles are required for the construction of such lens.To realize desired gradient index distribution,we carefully design a new type of crosschannel-shaped acoustic metamaterial,whose refractive index can be effectively modulated by simply changing the slit opening size.The distinct capabilities of the metamaterial Mikaelian lens in manipulating acoustic waves are experimentally verified with the fabricated sample.Simultaneous sound guiding and Talbot effects,which normally require respective geometrical and wave acoustic approximations,are observed in simulations and experiments.Furthermore,those effects of shaping acoustic wave propagations were validated within a relatively wide frequency range.Our study reveals how the conformal transformation method can help to bridge the ray acoustics with wave acoustics.It offers opportunities to the development of novel multifunctional acoustic devices for various applications,such as sound and particle manipulations.He Gao Xinsheng Fang Zhongming Gu Tuo Liu Shanjun Liang Yong Li Jie Zhu 2019Research2019,,1:0
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