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| 1 | Emerging pollutants in the environment:A challenge for water resource management显示文摘A significant number of emerging pollutants(EPs)resulting from point and diffuse pollution is present in the aquatic environment.These are chemicals that are not commonly monitored but have the potential to enter the environment and cause adverse ecological and human health effects.According to the NORMAN network,at least 700 substances categorized into 20 classes,have been identified in the European aquatic environment.In light of their potential impact action is urgently required.In this study,we present a concept that shows the current state of art and challenges for monitoring programs,fate and risk assessment tools and requirements for policies with respect to emerging pollutants as a base for sustainable water resource management.Currently,methods for sampling and analysis are not harmonized,being typically focused on certain EP classes.For a number of known highly hazardous EPs detection limits are too high to allow proper risk assessment.For other EPs such as microplastics method development is in its infancy.Advanced ultra-sensitive instrumental techniques should be used for quantitative determination of prioritized EPs in water,suspended matter,soil and biota.Data on EPs'and their metabolites'properties that determine their fate in the environment are often not available.National surveys on water quality often use different parameters for water quality assessment and often do not include EPs.A harmonized monitoring of surface and groundwater is not yet achieved and urgently required.Specific component integrated into models assessing the fate of EPs in a multi compartment environmental approach are missing and must be developed.The main goal of risk assessment is the overall protection of ecological communities in the aquatic environment and human health.New methods for assessing the cumulative risks from combined exposures to several stressors,including mixtures of EPs in a multi-scale approach are required.A combination of regulations and management measures with respect to use/emissions of EPs into the environment,as well as to their occurrence in the environment are fundamental to reach an efficient water resource management. | Violette Geissen Hans Mol Erwin Klumpp Günter Umlauf Marti Nadal Martine van der Ploeg Sjoerd E.A.T.M.van de Zee Coen J.Ritsema | 2015 | International Soil and Water Conservation Research2015，3，1： | 3 |
| 2 | Wnt signaling controls the phosphorylation status of beta-catenin显示文摘 | van Noort M Meeldijk J van der Zee R el al | | 0，，： | 2 |
| 3 | Expression and prognostic significance of thymidylate synthase (TS) in pancreatic head and periampullary cancer显示文摘 | J.A. van der Zee C.H.J. van Eijck W.C.J. Hop H. van Dekken B.M. Dicheva A.L.B. Seynhaeve G.A. Koning A.M.M. Eggermont T.L.M. ten Hagen | 2012 | European Journal of Surgical Oncology2012，，11： | 2 |
| 4 | A new technique of reversibly adsorbed phosphate显示文摘 | Fokkink L G J Van Reimsdijk W H | 1987 | Soil Sci Soc Am J1987，51，： | 1 |
| 5 | Thoracoscopic repair of esophageal atresia with distal fistula显示文摘 | van Der Zee DC Bax NM | 2003 | Surg Endosc2003，17，7： | 1 |
| 6 | Use of combined radiation and hyperthermia for gynecological cancer 显示文摘 | Franckena M van der Zee J | 2010 | Current Opinion in Obstetrics and Gynecology2010，22，1： | 1 |
| 7 | Alkalinization of urine samples preserves albumin concentrations during prolonged frozen stor- age in patients with diabetes mellitus 显示文摘 | Lambers Heerspink H J Nauta FL van der Zee CP | 2009 | Diabet Med2009，26，5： | 1 |
| 8 | Bcl-2 associated anthanogen-1(Bag-1)expression and prognostic value in pancreatic head and periampullary cancer显示文摘 | Van der Zee JA Ten Hagen TL Hop WC | 2013 | Eur J Cancer2013，49，2： | 1 |
| 9 | Long-term survival data of triple modality treatment of stage IIB-III- IVA cervical cancer with the combination of radiotherapy, chemotherapy and hyperthermia-an update显示文摘 | Westermann A Mella O Van Der Zee J | 2012 | Int J Hyper- thermia2012，28，6： | 1 |
| 10 | Short communication: influ- ence of preformed metal crowns ( Hall technique ) on the occlusal vertical dimension in the primary dentition显示文摘 | van der Zee V van Amerongen WE | 2010 | Eur Arch Paediatr Dent2010，11，5： | 1 |
| 11 | Simulating the effect of capillary flux on the soil water balance in a stochastic ecohydrological framework显示文摘 | Vervoort R W van der Zee S E A T | 2008 | Water Resources Research2008，44，8： | 1 |
| 12 | Effects of transient intracranial hypertension on lung fiuid and protein exchange显示文摘 | van der Zee H Neumann PH Minnear FL | 1983 | Apph Physiol1983，54，1： | 1 |
| 13 | Multi-phase flow modeling of air sparging显示文摘 | Van Dijke M Van der Zee I J Van Duijn C J | 1995 | Advances in Water Resources1995，18，6： | 1 |
| 14 | The Effects of Compression and Gas Diffusion Layers on the Performance of a PEM Fuel Cell显示文摘 | Woo-kum Lee Chien-Hsien Ho Van Zee J W | 1999 | Journal of Power Sources1999，84，： | 1 |
| 15 | Temperature data analysis for 22 patients with advanced cervical carcinoma treated in Rotterdam using radiotherapy,hyperthermia and chemotherapy:a reference point is needed显示文摘 | Fatehi D Van der Zee J Van der Wal E | 2006 | Int J Hyperthermia2006，22，4： | 1 |
| 16 | Wnt signaling controls the phosphorylation status of beta-catenin显示文摘 | Van Noort M Meeldijk J van der Zee R | 2002 | J Biol Chem2002，277，20： | 1 |
| 17 | Temperature data analysis for 22 patients with advanced cervical carcinoma treated in Rotterdam using radiotherapy, hyperthermia and chemotherapy: a reference point is needed显示文摘 | Fatehi D van der Zee J van der Wal E | 2006 | Int J Hyperthermia2006，22，4： | 1 |
| 18 | Evidence based selection of housekeeping genes显示文摘 | de Jonge H J Fehrmann R S de Bont E S Hofstra R M Gerbens F Kamps W A de Vries E G van der Zee A G te Meerman G J ter Elst A | | 0，，： | 1 |
| 19 | Laparoscopy-assisted anorectal pull-through in anorectal malformations: a reap- praisal显示文摘 | Van der Zee DC Dik P Beek FJ | 2013 | World J Surg2013，37，8： | 1 |
| 20 | A nomogram for predicting the likelihood of additional nodal metastasis in breast cancer patients with a positive sentinel node biopsy显示文摘 | Van Zee K Manasseh DE Bevilacqua JL | 2003 | Ann Surg Oncol2003，10，10： | 1 |
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