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| 1 | Utility of magnetic resonance imaging in anorectal disease显示文摘Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound have become popular in assessment of anatomy and staging of tumors, but have limitations. Magnetic resonance imaging (MRI) has the capability to fill in the gaps left open by more conventional imaging modalities and continues to be promising as the definitive imaging technique in the pelvis, especially with advancement of emerging technologies in this field. A comprehensive review of this topic has been undertaken. Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders. A review of the literature is performed to evaluate the use of MRI and other imaging modalities in these three areas. Preoperative imaging is useful in the evaluation of all three areas of anorectal disease. MRI is an effective tool in delineating anatomy and, when correlating with the specific clinical scenario, is an effective adjunct in clinical decision-making in order to optimize outcome. MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor. Its role is more well-established in some areas than in others, and there are still signif icant limitations. As technology advances, MRI will shed more light on a complex anatomical area. | Loren Berman Gary M Israel Shirley M McCarthy Jeffrey C Weinreb Walter E Longo | 2007 | World Journal of Gastroenterology2007，13，23： | 11 |
| 2 | Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study显示文摘AIM To increase our insight in the neuronal mechanisms underlying cognitive side-effects of antiepileptic drug(AED) treatment.METHODS The relation between functional magnetic resonance-acquired brain network measures, AED use, and cognitive function was investigated. Three groups of patients with epilepsy with a different risk profile for developing cognitive side effects were included: A 'low risk' category(lamotrigine or levetiracetam, n=16), an 'intermediate risk' category(carbamazepine, oxcarbazepine, phenytoin, or valproate, n=34) and a 'high risk' category(topiramate, n=5). Brain connectivity was assessed using resting state functional magnetic resonance imaging and graph theoretical network analysis. The Computerized Visual Searching Task was used to measure central information processing speed, a common cognitive side effect of AED treatment. RESULTS Central information processing speed was lower in patients taking AEDs from the intermediate and high risk categories, compared with patients from the low risk category. The effect of risk category on global efficiency was significant(P < 0.05, ANCOVA), with a significantly higher global efficiency for patient from the low category compared with the high risk category(P < 0.05, post-hoc test). Risk category had no significant effect on the clustering coefficient(ANCOVA, P > 0.2). Also no significant associations between information processing speed and global efficiency or the clustering coefficient(linear regression analysis, P > 0.15) were observed. CONCLUSION Only the four patients taking topiramate show aberrant network measures, suggesting that alterations in functional brain network organization may be only subtle and measureable in patients with more severe cognitive side effects. | Tamar M van Veenendaal Dominique M IJff Albert P Aldenkamp Richard H C Lazeron Paul A M Hofman Anton J A de Louw Walter H Backes Jacobus F A Jansen | 2017 | World Journal of Radiology2017，9，6： | 2 |
| 3 | Imaging of renal lesions: evaluation of fast MRI and helical CT显示文摘 | Walter C Kruessell M Gindele A | 2003 | Br J Radiol2003，76，910： | 2 |
| 4 | Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel显示文摘 | Mrrras M Mikhitarian K Walters C | 2001 | Int J Cancer2001，93，： | 1 |
| 5 | Protein serine/threonine phos-phatases :Structure, regulation,and functions in cell growth显示文摘 | MUMBY M C WALTER G | 1993 | Physiol Rev1993，73，4： | 1 |
| 6 | Methyl methanesulfonate(MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks 显示文摘 | Lundin C North M Erixon K Walters K Jenssen D Goldmanand SHA Helleday T | 2005 | Nucl Acids Res2005，33，12： | 1 |
| 7 | Soil carbon storage prediction in temperate hydromorphic soils by using morphologic index and digital elevation model显示文摘 | Chaplot V Bemoux M Walter C | 2001 | Soil Sci2001，102，： | 1 |
| 8 | The MAFT architecture for distributed fault - tolerance 显示文摘 | Kieckhafer R M Walter C J Finn A M | 1988 | IEEE Trans Computers1988，37，4： | 1 |
| 9 | Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping显示文摘 | Book C Walter J Paulsen M | 2008 | Nucleic Acids Res2008，36，10： | 1 |
| 10 | Identification of mi- crobial and thermogenic gas components from Upper Devonian black shale cores,Illinois and Michigan basins显示文摘 | Martini A M Walter L M Mclntosh J C | 2008 | AAFG Bul- letin2008，92，3： | 1 |
| 11 | Physical and related sensory properties of a swallowable bolus显示文摘 | Loret C Walter M Pineau N | 2011 | Physiology and Behavior2011，104，5： | 1 |
| 12 | Long-term outcome of split liver transplantation using right extended grafts in adulthood:a matched pair analysis显示文摘 | Wilms C Walter J Kaptein M | | 0，，06： | 1 |
| 13 | Adherent diamond-like carbon coatings on metals via plasma ion source ion implan- tation显示文摘 | Walter K C Nastasi M Munson C | 1997 | Surf Coat Technol1997，93，23： | 1 |
| 14 | Longevity of seeds in a genebank: species characteristics 显示文摘 | Walters C Wheeler L M Grotenhuis J M | 2005 | Seeds Sci Res2005，15，： | 1 |
| 15 | Neuroprotective effect of herpes simplex virus-mediated gene transfer of erythropoietin in hyperglycemic dorsal root ganglion neurons显示文摘 | Chattopadhyay M Walter C Mata M | 2009 | Brain2009，132，4： | 1 |
| 16 | Extensive microbial modificationof formation water geochemistry:Case study from a Midcontinentsedimentary basin,United States显示文摘 | McIntosh J C Walter L M Martini A M | 2004 | Geological Society of America Bulletin2004，116，56： | 1 |
| 17 | Social Resources and Strength of Ties:Structural Factors in Occupational Status Attainment显示文摘 | Nan Lin Walter M Ensel&John C Vaughn | 1981 | American Sociological Review1981，46，4： | 1 |
| 18 | In-plane-aligned membranes of carbon nanotubes显示文摘 | Walters D A Casavant M J Qin X C | 2001 | Chemical Physics Letters2001，338，1： | 1 |
| 19 | Microbial pro-duction and modification of gases in sedimentary basins:A geochemical case study from a Devonian shale gas play,Michigan basin显示文摘 | Martini A M Walter L M Ku T C W | 2003 | AAPG Bulletin2003，87，8： | 1 |
| 20 | Four-year metabolic out- come of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass显示文摘 | Keymeulen B Walter M Mathieu C | 2010 | Diabetologia2010，53，4： | 1 |
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