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| 1 | Serum leptin and soluble leptin receptor in non-alcoholic fatty liver disease显示文摘AIM: To determine the role of leptin system in non-al- coholic fatty liver disease (NAFLD) development by deli- neating the changes in serum levels of leptin and soluble leptin receptor (sOB-R). METHODS: Blood samples were collected from 30 consecutive patients with liver-biopsy-proven NAFLD and 30 patients with cholecystolithiasis (stationary phase) as controls. Serum leptin levels were determined by radio- immunoassay and concentration of sOB-R was measured by ELISA. Body mass index (BMI) was calculated for all subjects, and serum insulin, C-peptide, and lipoprotein levels were also detected. RESULTS: Mean serum leptin level and BMI in the NAFLD group were significantly higher than in the con- trols (both P < 0.001), but mean sOB-R level was lower in the NAFLD group when compared to the controls. Both men and women in the NAFLD group had higher mean serum leptin levels and lower sOB-R levels than did the men and women in the control group (all P < 0.001). The- re was a significant negative correlation between serum leptin and sOB-R levels (r = -0.725, P < 0.001). Multiva- riate analysis showed that the percentage of hepatocyte steatosis, sex, BMI, and homeostasis model assessment of insulin resistance (HOMA IR) were independently rela- ted to serum leptin levels. CONCLUSION: Elevated serum leptin seems to be afeature of steatosis, and serum leptin seems to increase as hepatocyte steatosis develops. An enhanced release of leptin is accompanied by an decrease in sOB-R con- centration, which suggests higher resistance of periphe- ral tissues towards the action of leptin. | Xiao-Dong Huang Yan Fan Hen Zhang Ping Wang Jing Ping Yuan Ming-Jie Li Xi-Yan Zhan | 2008 | World Journal of Gastroenterology2008，14，18： | 26 |
| 2 | Ultra-low procedural blank and the single-grain mica Rb-Sr isochron dating显示文摘Both low procedural blank and high-precision measurements of isotopic ratios are crucial for the analysis of micro samples. This study reports a chemical procedure of ultra-low blank for the high precision measurement of Sr isotopic ratios on micro samples (<1 ng level) using a new-type thermal ionization mass spectrometer IsoProbe-T, with a case study of single-grain Rb-Sr isochron dating on phlogopite from the Fuxian kimberlite in Liaoning Province. This method can be employed in studies of high resolution Rb-Sr geochronology and Sr isotopic geochemistry and thus will broaden application of the Rb-Sr isotopic system to earth sciences. | LI Qiuli HEN Fukun WANG Xiuli LI Xianghui LI Chaofeng | 2005 | Chinese Science Bulletin2005，50，24： | 15 |
| 3 | Evaluation of growth and reproduction as indicators of soil metal toxicity to the Collembolan, Sinella curviseta显示文摘实验室研究评估了 Sinella curviseta 布鲁克的敏感(Collembola:Entomobryidae ) 到选择重金属(Cu, Pb 和 Zn ) 。S 的幸存,复制和生长。curviseta 在与金属修改到 100, 200, 400, 800, 1600 和 3200 mg/kg 的集中的农业土壤的 4 星期的暴露测试被决定。结果在 Cu 和 Zn 的最高的集中(3200 mg/kg ) 在成年幸存和繁殖失败显示出减小。为 Cu 和 Zn 的 EC 50 繁殖 价值分别地是约 442 和 2760 mg/kg。Pb 的申请根本,层次与控制相比导致了大量子孙和没有重要死亡。成年生长率与控制相比为所有金属处理减少了,建议金属影响 S。在更慢的生长的 curviseta 新陈代谢和结果。我们证明复制比生长是一个稍微更敏感的参数。因为生长测试需要更少少年并且比繁殖测试花更少的时间,我们断定二个参数是补足的并且能被用于沾染物层次的更好的 ecotoxicological 评估。然而,在生长测试比繁殖测试作为更快的尚不致命的测试被接受以前,相对生长和繁殖敏感应该与更多的化学药品被测试。 | Jie Xu Xin Ke Paul Henning Krogh Yin Wang Yong-Ming Luo Jing Song | 2009 | Insect Science2009，16，1： | 8 |
| 4 | Applied anatomy for pituitary adenoma resection显示文摘背景垂体腺瘤是普通 intracranial 肿瘤,与在中国的升起的发生。切除是为这疾病的支柱治疗,并且经常经由 transfrontal , transsphenoidal 或 transpterional approaches.However 被执行,很少研究系统地探讨了涉及学习试图基于死尸和计算机断层摄影术( CT )图象研究建立与垂体腺瘤切除术相关的一些关键解剖大小的在场的这些 microsurgical procedures.The 的地区性的解剖。方法从解剖 analysis.Measurements 在垂体腺上面在大脑结构的颅骨追随者移动的底上,并且在头盖骨的 mid-sagittal 飞机上被做的死尸被用于的 30 随机选择的修理福尔马林的成年人领导标本。参数被考虑设计 3 上述普通 microsurgical 途径,并且用滑动 caliper 在每个头上获得了。从 30 个个人的多水平 CT 图象也为在与这些手术相关的里程碑结构之间的距离大小被使用。所有数据用 SPSS 11.5 软件受到统计分析。有的结果在 3 相对 CT 图象在死尸上测量的距离的统计上重要的差别( P0.05 )将外科的途径放与 transfrontal 有关的大小,即,从眉毛的拱门上级的中点的距离毗邻到内部颈动脉动脉(集成通信适配器)的头部的入口,集成通信适配器并且到集成通信适配器的膝的相反的方面入口。当地区性的解剖分析根据 transpterional 途径被执行时,统计上重要的差别也在在死尸和 CT 图象数据之间的距离大小的 3 个集合被发现,关于在在垂体附近的 pterion 和一些里程碑结构之间的距离。现在的学习提供解剖的钥匙和为垂体肿瘤切除术包含 3 条通常使用的外科的途径的 CT 图象大小的结论。数据含有当 CT 扫描结果能为操作提供珍贵指南时,小心和调整在垂体腺并且在外科的小径附近的附近为足够的肿瘤切除和关键血容器和神经的保护在外科期间被需要。 | LIU Liang LIU Zhi-xiong LIU Yun-sheng LIU Jing-fang ZENG Yu ZENG Zhi-cheng WANG Miao WANG Hao ZENG Chang-ming JIANG Xing-jun HEN Xin YANG Shu-guang | 2011 | Chinese Medical Journal2011，，15： | 4 |
| 5 | Supplementation of black rice pigment fraction improves antioxidant and anti-inflammatory statusin patients with coronary heart disease:显示文摘 | Wang Q Hen P Zhang M | 2007 | Asia Pac J Clin Nutr2007，161，： | 1 |
| 6 | A novel hydrophilic poly ( lactide-co- glycolide)/leeithin hybrid microspheres sintered scaffold for bone repair显示文摘 | Shi X Wang Y Hen L | 2010 | J Biomed Mater Res A2010，92，3： | 1 |
| 7 | Chemopreventive effects of tea in prostate cancer: green tea versus black tea显示文摘 | Henning SM Wang PW Heber D | 2011 | Mol Nutr Food Res2011，55，： | 1 |
| 8 | Sensitization to docetaxel in prostate cancer cells by green tea and quercetin显示文摘 | Wang P Henning SM Heber D | 2015 | J Nutr Biochem2015，26，4： | 1 |
| 9 | Adjuvantradiotherapy aftermodi- fled IvRR-Lewis esophagectomy: can itprevent lymph node recur- rence of themed the Racic esophageal carcinoma 显示文摘 | Hen G Wang Z LiuXY | 2009 | Ann Thorac Surg2009，87，6： | 1 |
| 10 | Energy saving and emission redaction revolutionizing China's environmental protection 显示文摘 | WANG Q C HEN Y | 2010 | Renewable & Sustainable Energy Reviews2010，14，1： | 1 |
| 11 | Electrical properties of a single microcoiled carbon fiber显示文摘 | Shen J Y C hen Z J Wang N L | 2006 | Appl Phys Lett2006，89，15： | 1 |
| 12 | Altered placental syncytin and its receptor ASCT2 expression in placental development and pre eclampsia显示文摘 | Hen CP Wang KG Chen CY | 2006 | BJOG2006，113，2： | 1 |
| 13 | Distributional features and fluxes of dissolved nitrogen, phosphorus and silicon in the Hangzhou Bay显示文摘 | GAO Sheng quan YU Guo hui WANG Yu hen | 1993 | Marine Chemistry1993，43，： | 1 |
| 14 | Effects of an endogenous nitric oxide synthase inhibitor on phorbol myristate acetate-induced acute lung injury in rats显示文摘 | Hen J Lin Shi Jye Chu David Wang | 2003 | Clinical and Experimental Pharmacology and Physiology2003，30，56： | 1 |
| 15 | Ophthalmoplegic migraine:migraine vari- ant or cranial neuralgia?显示文摘 | C hen PK Wang SJ | 2012 | Cephalalgia2012，32，7： | 1 |
| 16 | Transforming growth factor etenhances stem cell mediated postischemic myocardial protection显示文摘 | Hen'mann J L Abarbanell A M Wang Y | 2011 | Ann Thorae surg2011，92，5： | 1 |
| 17 | Interval kalman filtering 显示文摘 | hen G Wang J Shieh L S | 1997 | kerospace and Electronic Systems1997，33，1： | 1 |
| 18 | Novel spherical microporous carbon as anode material for Li-ion batterics显示文摘 | Wang Q Li H ( hen L O | 2002 | Solid State Ionics2002，15，： | 1 |
| 19 | AAA architecture for mobile IPv6 based on WLAN 显示文摘 | R C Wang C R Y hen H C Chao | 2004 | International Journal of Network Management2004，14，5： | 1 |
| 20 | Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells显示文摘 | Wang P Heber D Henning SM | 2012 | Nutr Cancer2012，64，4： | 1 |
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