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| 1 | Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer显示文摘AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(Ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of Ktrans and ve,generating two texture measures: Energy(E) and homogeneity.RESULTS: No significant changes were found for the mean and standard deviation for Ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors. | Jacobus FA Jansen Yonggang Lu Gaorav Gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 2 | The new human kallikrein gene family : implications in carcinogenesis 显示文摘 | Diamandis E P Yousef G M Luo L Y | 2000 | Trends Endocrinol Metab2000，11，2： | 1 |
| 3 | Haman tissue kallikreins:a family of new cancer biomarkers显示文摘 | Diamandis E P Yousef S | | 0，，21： | 1 |
| 4 | The human kallikrein gene family-implication in carcinogenesis显示文摘 | Diamandis E P Yousef G M Luo L Y | 2000 | Trends Endocrinol Metab2000，11，1： | 1 |
| 5 | Susceptibility of human rotavirus to ozone, high pressure, and pulsed electric field显示文摘 | KHADRE M A YOUSEF A E | 2002 | J Food Protect2002，65，9： | 1 |
| 6 | Identification and molecular characterization of a novel member of the singlec family显示文摘 | Foussias G Yousef G M Diamandis E P | 2000 | Genomics2000，67，1： | 1 |
| 7 | Inactivation kinetics of selected aerobic and anaerobic bacterial spores by pressureassisted thermal processing显示文摘 | AHN J BALASUBRAMANIAM V M YOUSEF A E | 2007 | International Journal of Food Microbiology2007，113，： | 1 |
| 8 | Spectrofluorimetric assessment of bacterial cell membrane damage by pulsed electric field显示文摘 | Unal R Yousef A E Dunne C P | 2002 | Innovative Food Science & Emerging Technologies2002，3，3： | 1 |
| 9 | Adaptive fuzzy decentralized control for interconnected MIMO nonlinear subsystems显示文摘 | Yousef H Hamdy M Madbouly E | 2009 | Automatica2009，45，2： | 1 |
| 10 | The new human tissue kallikre ingene family: structure, function, and association to disease显示文摘 | Yousef G M Diamandis E P | 2001 | Endocr Rev2001，22，2： | 1 |
| 11 | Use of ozone to inactivate microorganisms on lettuce显示文摘 | Kim J-G Yousef A E Chism G W | 1999 | Food Safety1999，19，1： | 1 |
| 12 | The role of echocardiography in guiding management in dilated cardiomyopathy 显示文摘 | Thomas D E Wheeler R Yousef Z R | 2009 | Eur J Echocardiography2009，10，8： | 1 |
| 13 | Deltame- thrin-induced oxidative damage and biochemical alterations in rat and its attenuation by Vitamin E 显示文摘 | Yousef M I Awad T I Mohameda E H | 2006 | Toxicology2006，227，： | 1 |
| 14 | Studies on the movement on Ni in wheat rhizosphere显示文摘 | Yousef R A Abd E A Hilal M H | 1987 | Plant Nutr1987，，： | 1 |
| 15 | Human kallilreins:common structural features,sequence analysis and evaluation显示文摘 | Yousef G M Diamandis E P | 2003 | Curr Genomics2003，276，1： | 1 |
| 16 | Rapid detection and differentiation of AlicyclobaciUus species in fruit juice using hydrophobic grid membranes and attenuated total reflectance infrared microspectroscopy显示文摘 | Grasso E Yousef A Castellvi S | 2009 | J Agr Food Chem2009，57，10： | 1 |
| 17 | Predictors of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage : A cardiac fo- cus显示文摘 | Yousef K Crago E Kuo CW | 2010 | Neurocrit Care2010，13，3： | 1 |
| 18 | Intermittent versus continuous total androgen blockade in the treatment of patients with advanced hormone-naive prostate cancer: results of a prospective randomized multicenter trial显示文摘 | de Leval J Boca P Yousef E | 2002 | Clin Prostate Cancer2002，1，3： | 1 |
| 19 | Effect of rare earth (Pr2 O3,Nd2 O3,Sm2 O3,Eu2 O3,Gd2 O3 and Er2 O3) on the acoustic properties of glass belonging to bismuth borate system显示文摘 | Yousef E S El-Adawy A El-Kheshkhany N | | 0，，01： | 1 |
| 20 | New nomenclature for the human tissue kallikrein gene family显示文摘 | Diamandis E P Yousef G M Clements J | 2000 | Clin Chem2000，46，11： | 1 |
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