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| 1 | On the origin and continuing evolution of SARS-CoV-2显示文摘The SARS-Co V-2 epidemic started in late December 2019 in Wuhan, China, and has since impacted a large portion of China and raised major global concern. Herein, we investigated the extent of molecular divergence between SARS-CoV-2 and other related coronaviruses. Although we found only 4% variability in genomic nucleotides between SARS-CoV-2 and a bat SARS-related coronavirus(SARSr-CoV;Ra TG13), the difference at neutral sites was 17%, suggesting the divergence between the two viruses is much larger than previously estimated. Our results suggest that the development of new variations in functional sites in the receptor-binding domain(RBD) of the spike seen in SARS-Co V-2 and viruses from pangolin SARSr-Co Vs are likely caused by natural selection besides recombination. Population genetic analyses of 103 SARS-CoV-2 genomes indicated that these viruses had two major lineages(designated L and S), that are well defined by two different SNPs that show nearly complete linkage across the viral strains sequenced to date. We found that L lineage was more prevalent than the S lineage within the limited patient samples we examined. The implication of these evolutionary changes on disease etiology remains unclear.These findings strongly underscores the urgent need for further comprehensive studies that combine viral genomic data, with epidemiological studies of coronavirus disease 2019(COVID-19). | Xiaolu Tang Changcheng Wu Xiang Li Yuhe Song Xinmin Yao Xinkai Wu Yuange Duan Hong Zhang Yirong Wang Zhaohui Qian Jie Cui Jian Lu | 2020 | National Science Review2020，7，6： | 67 |
| 2 | In-situ fabrication of PtSe2/GaN heterojunction for self-powered deep ultraviolet photodetector with ultrahigh current on/off ratio and detectivity显示文摘The research of ultraviolet photodetectors(UV PDs)have been attracting extensive attention,due to their important applications in many areas.In this study,PtSe2/GaN heterojunction is in-situ fabricated by synthesis of large-area vertically standing two-dimensional(2D)PtSe2 film on n-GaN substrate.The PtSe2/GaN heterojunction device demonstrates excellent photoresponse properties under illumination by deep UV light of 265 nm at zero bias voltage.Further analysis reveals that a high responsivity of 193 mA·W^-1,an ultrahigh specific detectivity of 3.8 × 10^14 Jones,linear dynamic range of 155d B and current on/off ratio of^10^8,as well as fast response speeds of 45/102μs were obtained at zero bias voltage.Moreover,this device response quickly to the pulse laser of 266 nm with a rise time of 172 ns.Such high-performanee PtSe2/GaN heteroj u nction UV PD demonstrated in this work is far superior to previously reported results,suggesting that it has great potential for deep UV detection. | Ranran Zhuo Longhui Zeng Huiyu Yuan Di Wu Yuange Wang Zhifeng Shi Tingting Xu Yongtao Tian Xinjian Li Yuen Hong Tsang | 2019 | Nano Research2019，12，1： | 11 |
| 3 | Energy-Efficient Mapping for 3D NoC Using Logistic Function Based Adaptive Genetic Algorithms显示文摘The problem of mapping application tasks is one of key issues in 3D Network on chip(3D NoC) design. A novel Logistic function based adaptive genetic algorithm(LFAGA) is proposed for energy-aware mapping of homogeneous 3D NoC. We formulate the mapping problem and show the Standard genetic algorithm(SGA). The LFAGA is presented in detail with the goal of obtaining higher convergence speed while preventing the premature convergence. Experimental results indicate that the proposed LFAGA is more efficient than previously proposed Chaos-genetic mapping algorithm(CGMAP). In the experiments, a randomly generated task graph of size 27 is mapped to a 3D NoC of size 3×3×3, the convergence speed of LFAGA is 2.55 times faster than CGMAP in the best condition. When the task size increases to 64 and the 3D NoC size extends to 4×4×4, LFAGA is 2.31 times faster compared to CGMAP. For the No C sizes in the range from 3×3×2 to 4×4×4, solutions obtained by the LFAGA are consistently better than the CGMAP. For example, in the experiment of size 4×4×4, the improvement of final result reaches 30.0% in term of energy consumption. For a real application of size 3×4×2, 18.6% of energy saving can be achieved and the convergence speed is 1.58 times faster than that of the CGMAP. | WANG Jiawen LI Li WANG Zhongfeng ZHANG Rong ZHANG Yuang | 2014 | Chinese Journal of Electronics2014，23，2： | 5 |
| 4 | Fermented mixed feed alters growth performance,carcass traits,meat quality and muscle fatty acid and amino acid profiles in finishing pigs显示文摘This study was conducted to investigate the effects of fermented mixed feed(FMF)on growth performance,carcass traits,meat quality,muscle amino acid and fatty acid composition and mRNA expression levels of genes related to lipid metabolism in finishing pigs.In the present study,144 finishing pigs(Duroc×Berkshire×Jiaxing Black)were randomly allocated to 3 dietary treatments with 4 replicate pens per group and 12 pigs per pen.The dietary treatments included a basal diet(CON),a basal diet+5%FMF and a basal diet+10%FMF.The experiment lasted 38 d after 4 d of acclimation.The results showed that 5%and 10%FMF significantly increased the average daily gain(ADG)of the females but not the males(P<0.05),but FMF supplementation showed no impact on carcass traits.Moreover,10%FMF supplementation increased the meat color45 min and meat color24 h values,while it decreased the shear force relative to CON(P<0.05).In addition,10%FMF significantly increased the contents of flavor amino acids(FAA),total essential AA(EAA),total non-EAA(NEAA)and total AA relative to CON(P<0.05).Furthermore,the diet supplemented with 10%FMF significantly increased the concentration of n-3 polyunsaturated fatty acids(PUFA),n-6 PUFA and total PUFA,and the PUFA to saturated fatty acids ratio(P<0.05),suggesting that FMF supplementation increased meat quality.Moreover,compared with the CON,10%FMF supplementation increased the mRNA expression of lipogenic genes,including CEBPα,PPARγ,SREBP1 and FABP4,and upregulated the expression of unsaturated fatty acid synthesis(ACAA1 and FADS2).Together,our results suggest that 10%FMF dietary supplementation improved the female pigs’growth performance,improved the meat quality and altered the profiles of muscle fatty acids and amino acids in finishing pigs.This study provides a reference for the production of high-quality pork. | Shiqi Liu Man Du Yuang Tu Wenjing You Wentao Chen Guoliang Liu Junyue Li Yizhen Wang Zeqing Lu Tenghao Wang Tizhong Shan | 2023 | Animal Nutrition2023，，1： | 4 |
| 5 | Genome-wide analysis and identification of cytokinin oxidase/dehydrogenase(CKX) gene family in foxtail millet(Setaria italica)显示文摘Cytokinin oxidase/dehydrogenase(CKX; EC.1.5.99.12) regulates cytokinin(CK) level in plants and plays an essential role in CK regulatory processes. CKX proteins are encoded by a small gene family with a varying number of members in different plants. In spite of their physiological importance, systematic analyses of SiCKX genes in foxtail millet have not yet been examined. In this paper, we report the genome wide isolation and characterization of SiCKXs using bioinformatic methods. A total of 11 members of the family were identified in the foxtail millet genome. SiCKX genes were distributed in seven chromosomes(chromosome 1, 3, 4, 5, 6, 7, and 11). The coding sequences of all the SiCKX genes were disrupted by introns, with numbers varying from one to four. These genes expanded in the genome mainly due to segmental duplication events. Multiple alignment and motif display results showed that all SiCKX proteins share FAD- and CK-binding domains. Putative cis-elements involved in Ca2+-response, abiotic stress response, light and circadian rhythm regulation, disease resistance and seed development were present in the promoters of SiCKX genes. Expression data mining suggested that SiCKX genes have diverse expression patterns. Real-time PCR analysis indicated that all 11 SiCKX genes were up-regulated in embryos under 6-BA treatment, and some were NaCl or PEG inducible. Collectively, these results provide molecular insights into CKX research in plants. | Yuange Wang Huaihua Liu Qingguo Xin | 2014 | The Crop Journal2014，2，4： | 3 |
| 6 | Protein farnesylation negatively regulatesbrassinosteroid signaling via reducing BES1 stabilityinArabidopsis thaliana^(∞)显示文摘Brassinosteroids(BRs)are a group of steroidal phytohormones,playing critical roles in almost all physiological aspects during the life span of a plant.In Arabidopsis,BRs are perceived at the cell surface,triggering a reversible phosphorylation-based signaling cascade that leads to the activation and nuclear accumulation of a family of transcription factors,represented by BES1 and BZR1.Protein famesylation is a type of post-translational modification,functioning in many important cellular processes.Previous studies demonstrated a role of famesylation in BR biosynthesis via regulating the endoplasmic reticulum localization of a key bassino-lide(BL)biosynthetic enzyme BR6ox2.Whether such a process is also involved in BR signaling is not understood.Here,we demonstrate that protein famesylation is involved in mediating BR signaling in Arabidopsis.A loss-of-function mutant of EN HANCED RESPONSE TO ABA 1(iERA1).encoding a(3 subunit of the protein famesyl transferase hoi oenzyme,can alter the BL sensitivity of bak1~4 from a reduced to a hypersensitive level,era 7 can partially rescue the BR defective phenotype of a hetero zygous mutant of bin2-1,a gain-of function mutant of BIN2 which encodes a negative regulator in the BR signaling.Our genetic and biochemical analyses revealed that ERA1 plays a significant role in regulating the protein stability of BES1. | Zengxiu Feng Hongyong Shi Minghui Lv Yuang Ma Jia Li | 2021 | Journal of Integrative Plant Biology2021，63，7： | 3 |
| 7 | Improvement of copper tolerance of Arabidopsis by transgenic expression of an allene oxide cyclase gene,GhA OC1, in upland cotton(Gossypium hirsutum L.)显示文摘Allene oxide cyclase(AOC, E 5.3.99.6) is an essential enzyme in the jasmonic acid(JA)biosynthetic pathway and mediates a wide range of adaptive responses. In this report, five AOC genes(Gh AOC1–Gh AOC5) were cloned from upland cotton(Gossypium hirsutum L.),sequenced, and characterized. Real-time PCR analysis indicated that the transcripts of Gh AOCs were abundantly expressed in roots and less in fibers, and regulated in cotton plants under methyl jasmonate(Me JA) and Cu Cl2 stresses. To investigate the role of Gh AOC under copper stress, transgenic Arabidopsis plants overexpressing cotton Gh AOC1 under control of the Cauliflower mosaic virus 35S(Ca MV 35S) promoter were generated. Compared to untransformed plants, Gh AOC1-overexpressing Arabidopsis thaliana plants exhibited markedly higher survival rate, shoot fresh weight, shoot dry weight, and photosynthetic efficiency, and reduced cell membrane damage and lipid peroxidation under copper stress.This study provides the first evidence that Gh AOC1 plays an important role in copper stress tolerance. | Yuange Wang Huaihua Liu Qingguo Xin | 2015 | The Crop Journal2015，3，4： | 2 |
| 8 | Effects of SRT and DO on nutrient removal in a combined AS-biofilm process 显示文摘 | Chuang S H Ouyang C F Yuang H C | 1997 | Water Sci Technol1997，36，： | 1 |
| 9 | The contractible edges of 5-connected graphs显示文摘 | YUANG Xu-dong | 1994 | J Guangxi Normal University1994，，3： | 1 |
| 10 | Pilot study of a fluidized-pellet-bed technique for simultaneous soild/liquid separation and sludge thickening in a sewage treatment plant 显示文摘 | WANG X C JIN P K YUANG H L | 2004 | Water Science & Technology2004，49，10： | 1 |
| 11 | Status of persistent organic pollutants in the sediment from several estuanies in china 显示文摘 | YUANG D YANG D WADE T L | 2001 | Environmental Pollution2001，114，1： | 1 |
| 12 | Self-balancing of the Clamping-capacitor-voltages in the Multilevel Capacitor- clamping-inverter under Sub-harmonic PWM Modulation 显示文摘 | Yuang Xiaoming Stemmler H Barbi I | 2001 | IEEE Transactions on Power Electronics2001，16，2： | 1 |
| 13 | Joint wavelet and spatial transformation for digital watermarking显示文摘 | Tsai M Yuang K Chen Y | 2000 | IEEE Transactions on Consumer Electronics2000，46，1： | 1 |
| 14 | Joint wavelet and spatial transformation for digital watermarking显示文摘 | Tsai M Yuang K Chen Y | 2000 | IEEE Trans on Consumer Electronics2000，46，1： | 1 |
| 15 | Dynamic Video Playout Smoothing Method for Multimedia Applications显示文摘 | Yuang M C Liang S T Chen Y G | 1998 | Multimedia Tools and Applications1998，6，1： | 1 |
| 16 | Joint wavelet and spatial transformation for digital watermarking显示文摘 | TSAI M YUANG K CHEN Y | 2000 | IEEE Transactions on Consumer Electronics2000，46，1： | 1 |
| 17 | Institutional arrangements and construction safety in China: An empirical examination 显示文摘 | YUANG Ping | 2009 | Construc- tion Management and Economics2009，27，5： | 1 |
| 18 | Photothermal deflection and photoluminescence studies of CdS and CdSe quantum dots显示文摘 | Yuang Yushen Chen Yangfang Lee Yangyao | 1994 | Appl Phys1994，76，304： | 1 |
| 19 | An application of real-time error com- pensation on a turning center 显示文摘 | Lo C I-I Yuang J X Ni J | 1995 | International Journal of Machine Tools & Manufacture1995，，12： | 1 |
| 20 | Integrated tool path and feed rate optimization for the finishing machining of 3D plane surfaces显示文摘 | Feng His yuang Su Ning | 2000 | International Journal of Machine Tools and Manufacture2000，40，11： | 1 |
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