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| 1 | An X-ray and DFT Computational Study on 1-(Naphthalene-2-yl)-2-(1H-pyrazol-1-yl) ethanone O-butyl Oxime显示文摘The title compound, 1-(naphthalene-2-yl)-2-(1H-pyrazol-1-yl)ethanone O-butyl oxime, I, was synthesized. The crystal and molecular structures of I were determined by IR, 1H-NMR, mass spectrum, elemental analysis and X-ray single crystal diffraction. Molecular geometry from X-ray experiment of I in the ground state was compared using the Density Functional Theory (DFT) with B3LYP/6-311G(d,p) basis set. In addition, DFT calculation, molecular electrostatic potentials (MEP) and frontier molecular orbitals of I were performed at the B3LYP/6-311G(d,p) level of the theory. | Zarife Sibel SAHN Zeynep ZDEMR Arzu KARAKURT Samil ISIK | 2012 | Chinese Journal of Structural Chemistry2012，31，2： | 2 |
| 2 | Bone marrow microenvironment: The guardian of leukemia stem cells显示文摘Bone marrow microenvironment (BMM) is the main sanctuary of leukemic stem cells (LSCs) and protects these cells against conventional therapies. However, it may open up an opportunity to target LSCs by breaking the close connection between LSCs and the BMM. The elimination of LSCs is of high importance, since they follow cancer stem cell theory as a part of this population. Based on cancer stem cell theory, a cell with stem cell-like features stands at the apex of the hierarchy and produces a heterogeneous population and governs the disease. Secretion of cytokines, chemokines, and extracellular vesicles, whether through autocrine or paracrine mechanisms by activation of downstream signaling pathways in LSCs, favors their persistence and makes the BMM less hospitable for normal stem cells. While all details about the interactions of the BMM and LSCs remain to be elucidated, some clinical trials have been designed to limit these reciprocal interactions to cure leukemia more effectively. In this review, we focus on chronic myeloid leukemia and acute myeloid leukemia LSCs and their milieu in the bone marrow, how to segregate them from the normal compartment, and finally the possible ways to eliminate these cells. | Mohammad Houshmand Teresa Mortera Blanco Paola Circosta Narjes Yazdi Alireza Kazemi Giuseppe Saglio Mahin Nikougoftar Zarif | 2019 | World Journal of Stem Cells2019，11，8： | 2 |
| 3 | Cochleates:new lipid-based drug delivery system显示文摘 | Zarif L Graybill J R Perlin D Mannino R J | 2000 | J Liposome Res2000，10，： | 1 |
| 4 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast J2005，11，4： | 1 |
| 5 | Efficacy of orally delivered cochleates containing amphotericin B in a murine model of aspergillosis显示文摘 | Delmas G Park S Chen Z W Tan F Kashiwazaki R Zarif L | 2002 | Antimicrob Agents Chemother2002，46，： | 1 |
| 6 | Correlation of Her-2/neu gene amplification with other prognosticand predictive factors in female breast carcinoma显示文摘 | Ariga R Zarif A Korasiclc J | 2005 | Breast J2005，11，4： | 1 |
| 7 | Pharmacokinetics and tissue distribution after intravenous administration of a single dose of amphotericin B cochleates, a new lipid-based delivery system显示文摘 | Segarra I Movshin D A Zarif L | 2002 | J Pharm Sci2002，91，： | 1 |
| 8 | Hemorrhagic shockand encephalopathy syndrome:Neurologic features显示文摘 | Erdal ince Zarife kuloglu Zekeriya akinci | 2000 | PediatricEmeng Care2000，16，4： | 1 |
| 9 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast2005，11，4： | 1 |
| 10 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast J2005，11，4： | 1 |
| 11 | Correlation of Her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma 显示文摘 | Ariga R Zarif A Kaxasick J | 2005 | Breast J2005，11，4： | 1 |
| 12 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinom a显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast J2005，11，4： | 1 |
| 13 | Correlation of her-2/neu geneamplification with other prognostic and predictive factors in femalebreast carcinoma显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast J2005，11，4： | 1 |
| 14 | Predominant RET germline mutations in exons 10,11, and 16 in Iranian patients with hereditary medullary thy- roid carcinoma 显示文摘 | Hedayati M Zarif Yeganeh M Sheikhol Eslami S | 2011 | J Thyroid Res2011，2011，： | 1 |
| 15 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | Zarif A Korasick J | 2005 | Breast2005，11，4： | 1 |
| 16 | Multi-objective optimization of seismically isolated high-rise building structures using genetic algorithms 显示文摘 | Pourzeynali S Zarif M | 2008 | Journal of Sound and Vibration2008，311，： | 1 |
| 17 | Apolipoprotein E polymorphisms status in Iranian patients with multiple sclero- sis 显示文摘 | Rafiei M Zarif Yeganeh M Sheikholeslami S | 2012 | Journal of the Neurological Sci- ences2012，320，12： | 1 |
| 18 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | Ariga R Zarif A Korasick J | 2005 | Breast J2005，11，4： | 1 |
| 19 | Transient Flow and Pigging Operation in Gas-Liquid Two Phase Pipelines显示文摘 | S M Hosseinalipour A Salimil A Zarif Khalili | 2007 | 16th Australasian Fluid Mechanics Conference Crown Plaza Gold Coast Australia2007，2007，： | 1 |
| 20 | Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinoma显示文摘 | ARIGA R ZARIF A KORASICK J | | 0，，04： | 1 |
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