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| 1 | Evolution of planetary boundary layer under different weather conditions,and its impact on aerosol concentrations显示文摘一个领域实验在天津被进行,从 2010 年 9 月 930 日的中国,在表面空气污染物质上集中了于行星的边界层(PBL ) 和它的影响的进化。实验使用了三台遥感仪器,风侧面雷达( WPR ),微波辐射计( MWR )和微脉搏的激光雷达( MPL ),到检测风,温度,和喷雾器 backscattering 系数并且到的垂直侧面测量表面污染物质的垂直侧面(喷雾器,公司, SO2 , NOx ),并且也从 255-m 收集了声音的风速表数据气象学的塔。把大小基于这些, PBL 的进化被估计。平均 PBL 高度在夜间期间在 noon/afternoon-time,和 200300 m 期间是大约 10001300 m。PBL 高度和喷雾器集中是相关反的在期间清楚并且薄雾条件。当平均喷雾器集中分别地是在薄雾和晴朗天空条件下面的 52 和 17 g/m3 时,平均最大的 PBL 高度是 1.08 和 1.70 km。太阳的放射上的喷雾器和云的影响基于从 255-m 收集的声音的风速表数据被观察气象学的塔。当 PBL 的镇压结构进一步削弱了污染物质的散开时,热流动被发现被薄雾(重污染) 或云显著地减少了,它趋于压抑 PBL 的发展,导致重污染。这个可能的积极反馈周期(更多的喷雾器降低 PBL 高度更多的喷雾器) 将在大城市为重地面污染导致一个加速过程。 | Jiannong Quan Yang Gao Qiang Zhang Xuexi Tie Junji Cao Suqin Han Junwang Meng Pengfei Chen Delong Zhao | 2013 | Particuology2013，11，1： | 51 |
| 2 | Measurement and Interpretation of Connectivity of Chinese Cities in World City Network,2010显示文摘This is an empirical paper that measures and interprets the position of Chinese cities in the world city network in 2010. Building on a specification of the world city network as a′interlocking network′in which business services firms play the crucial role in city network formation, information is gathered about the presence of global service firms in cities. This information is converted into data to provide the′service value′of a city for a firm′s provision of corporate services in a 526(cities)×175(firms) matrix. These data are then used as the input to the interlocking network model in order to measure cities′connectivity and its predominant geographical orientation. Here we focus on the position of some key Chinese cities in this regard, and discuss and interpret results in the context of the urban dimensions of the′opening up′of the Chinese economy. | Ben DERUDDER Peter J TAYLOR Michael HOYLER NI Pengfei LIU Xingjian ZHAO Miaoxi SHEN Wei Frank WITLOX | 2013 | Chinese Geographical Science2013，23，3： | 40 |
| 3 | Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment via the HMGB1/RAGE/IL-8 axis显示文摘Objective:Neutrophil extracellular traps(NETs)produced by tumor-infiltrating neutrophils(TINs)are associated with poor prognosis in patients with several types of cancer.However,the mechanisms underlying the involvement of NETs in glioma progression remain largely unknown.This study aimed to elucidate the roles of NETs in biological processes that drive the crosstalk between glioma progression and the tumor microenvironment.Methods:Neutrophil infiltration and NETs formation were investigated in glioma tissue through immunohistochemistry,and their relationships with clinicopathological features and outcomes were statistically evaluated.The effects of NETs on glioma cell progression were studied in a co-culture system.In vivo and in vitro experiments validated the reactive oxygen species activity and cytokine production of TINs,as well as the ERK signaling pathway activation and the metastasis of gliomas.Results:Neutrophil infiltration and NETs formation were induced in high-grade glioma compared with low-grade glioma.NETs induced by TINs were determined to be an oncogenic marker of high-grade gliomas and to be involved in cell proliferation and invasion.NETs overproduction promoted glioma cell proliferation,migration,and invasion.Furthermore,HMGB1 was found to bind to RAGE and activate the NF-κB signaling pathway in vitro.In addition,NETs stimulated the NF-κB signaling pathway,thus promoting IL-8 secretion in glioblastoma.Subsequently,IL-8 recruited neutrophils which in turn mediated NETs formation via the PI3 K/AKT/ROS axis in TINs.Conclusions:Our results suggest that NETs produced by TINs mediate the crosstalk between glioma progression and the tumor microenvironment by regulating the HMGB1/RAGE/IL-8 axis.Targeting NETs formation or IL-8 secretion may be an effective approach to inhibit glioma progression. | Caijun Zha Xiangqi Meng Lulu Li Shan Mi Da Qian Ziwei Li Pengfei Wu Shaoshan Hu Shihong Zhao Jinquan Cai Yanhong Liu | 2020 | Cancer Biology & Medicine2020，17，1： | 19 |
| 4 | Effects of dietary supplementation of Artemisia argyi aqueous extract on antioxidant indexes of small intestine in broilers显示文摘The present study was conducted to investigate the effect of Artemisia argyi aqueous extract(AAE) on antioxidant indexes in the small intestine. A total of 192 Arbor Acre broiler chickens(one-day-old) were randomly divided into 4 treatments with 6 replicates of 8 chickens. These 4 diets were formulated by adding 0, 500,1,000 and 2,000 mg/kg AAE to the basal diet. The results showed as follows: 1) compared with the control, the total antioxidant capacity(T-AOC) in ileum for the 2,000 mg/kg treatment group was significantly increased at 21 days of age(P < 0.05); the T-AOC levels in jejunum and ileum were significantly increased in broilers supplemented with 500 mg/kg AAE at 42 days of age(P < 0.05), and the T-AOC levels in jejunum and ileum were significantly improved in 1,000 mg/kg treatment group(P < 0.01), 2) At 21 days of age, supplementation of 500 mg/kg AAE significantly increased the catalase(CAT) activity of small intestine, and the glutathione peroxidase(GSH-Px) activity of jejunum was improved(P < 0.01), meanwhile, the GSH-Px activity of duodenum and the total superoxide dismutase(T-SOD) activity of duodenum and jejunum were significantly higher than those of the control group(P < 0.05); supplementation of 1,000 mg/kg AAE significantly increased the CAT activity of duodenum and ileum and the GSH-Px activity of duodenum and jejunum(P < 0.05), and the ileum GSH-Px activity was significantly increased(P < 0.01); supplementation of 2,000 mg/kg AAE significantly increased the CAT activity of duodenum and ileum(P < 0.05). At 42 days of age, supplementation of 500 mg/kg AAE significantly increased the GSH-Px activity of ileum and the T-SOD activity of duodenum(P < 0.05),meanwhile, the T-SOD activity of jejunum was significantly increased(P < 0.01); supplementation of1,000 mg/kg AAE significantly increased the CAT activity of jejunum and the T-SOD activity of ileum(P < 0.01), and the GSH-Px activity of jejunum was significantly increased(P < 0.05); supplementation of2,000 mg/kg AAE significantly increased the T-SOD activity of ileum(P < 0.05), but significantly decreased the CAT activity of ileum and the GSH-Px activity of jejunum(P < 0.05). 3) The malondialdehyde(MDA) levels of 3 AAE supplementation groups were significantly decreased at 21 and 42 days of age(P < 0.05). The results suggested that dietary supplementation with AAE could improve the antioxidative capacity of small intestine in broilers. | Fei Zhao Binlin Shi Dengsheng Sun Hongyan Chen Manman Tong Pengfei Zhang Xiaoyu Guo Sumei Yan | 2016 | Animal Nutrition2016，，3： | 18 |
| 5 | Prevention and treatment technologies of railway tunnel water inrush and mud gushing in China显示文摘Water inrush and mud gushing are one of the biggest hazards in tunnel construction. Unfavorable geological sections can be observed in almost all railway tunnels under construction or to be constructed, and vary in extent. Furthermore, due to the different heights of mountains and the lengths of tunnels, the locations of the unfavorable geological sections cannot be fully determined before construction, which increases the risk of water inrush and mud gushing. Based on numerous cases of water inrush and mud gushing in railway tunnels, the paper tries to classify water inrush and mud gushing in railway tunnels in view of the conditions of the surrounding rocks and meteorological factors associated with tunnel excavation. In addition, the causes of water inrush and mud gushing in combination of macroand micromechanisms are summarized, and site-specifc treatment method is put forward. The treatment methods include choosing a method of advance geological forecast according to risk degrees of different sections in the tunnel, determining the items of predictions, and choosing the appropriate methods, i.e. draining-oriented method, blocking-oriented method or draining-and-blocking method. The treatment technologies of railway water inrush and mud gushing are also summarized, including energy relief and pressure relief technology, advance grouting technology, and advance jet grouting technology associated with their key technical features and applicable conditions. The results in terms of treatment methods can provide reference to the prevention and treatment of tunnel water inrush and mud gushing. | Yong Zhao Pengfei Li Siming Tian | 2013 | Journal of Rock Mechanics and Geotechnical Engineering2013，5，6： | 16 |
| 6 | Differential study of DCE-MRI parameters in spinal metastatic tumors, brucellar spondylitis and spinal tuberculosis显示文摘Objective: In the present study, spinal metastatic tumors, brucellar spondylitis and spinal tuberculosis were quantitatively analyzed using dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) to assess the value of DCE-MRI in the differential diagnosis of these diseases.Methods: Patients with brucellar spondylitis, spinal tuberculosis or a spinal metastatic tumor(30 cases of each)received conventional MRI and DCE-MRI examination. The volume transfer constant(K^(trans)), rate constant(K_(ep)),extravascular extracellular volume fraction(V_e) and plasma volume fraction(V_p) of the diseased vertebral bodies were measured on the perfusion parameter map, and the differences in these parameters between the patients were compared.Results: For pathological vertebrae in cases of spinal metastatic tumor, brucellar spondylitis and spinal tuberculosis, respectively, the K^(trans) values(median ± quartile pitch) were 0.989±0.014, 0.720±0.011 and0.317±0.005 min^(–1); the K_(ep) values were 2.898±0.055, 1.327±0.017 and 0.748±0.006 min^(–1); the V_e values were 0.339±0.008, 0.542±0.013 and 0.428±0.018; the V_p values were 0.048±0.008, 0.035±0.004 and 0.028±0.009; the corresponding H values were 50.25(for K_(trans)), 52.47(for K_(ep)), 48.33(for V_e) and 46.56(for V_p), and all differences were statistically significant(two-sided P<0.05).Conclusions: The quantitative analysis of DCE-MRI has a certain value in the differential diagnosis of spinal metastatic tumor, brucellar spondylitis and spinal tuberculosis. | Pengfei Qiao Pengfei Zhao Yang Gao Yuzhen Bai Guangming Niu | 2018 | Chinese Journal of Cancer Research2018，30，4： | 16 |
| 7 | Removal of elemental mercury by iodine-modified rice husk ash sorbents显示文摘Iodine-modified calcium-based rice husk ash sorbents(I2/CaO/RHA) were synthesized and characterized by X-ray diffraction,X-ray fluorescence,and N2 isotherm adsorption/desorption.Adsorption experiments of vapor-phase elemental mercury(Hg0) were performed in a laboratory-scale fixed-bed reactor.I2/CaO/RHA performances on Hg0 adsorption were compared with those of modified Ca-based fly ash sorbents(I2/CaO/FA) and modified fly ash sorbents(I2/FA) .Effects of oxidant loading,supports,pore size distribution,iodine impregnation modes,and temperature were investigated as well to understand the mechanism in capturing Hg0.The modified sorbents exhibited reasonable effciency for Hg0 removal under simulated flue gas.The surface area,pore size distribution,and iodine impregnation modes of the sorbents did not produce a strong effect on Hg0 capture effciency,while fair correlation was observed between Hg0 uptake capacity and iodine concentration.Therefore,the content of I2 impregnated on the sorbents was identified as the most important factor influencing the capacity of these sorbents for Hg0 uptake.Increasing temperature in the range of 80-140°C caused a rise in Hg0 removal.A reaction mechanism that may explain the experimental results was presumed based on the characterizations and adsorption study. | Pengfei Zhao,Xin Guoff,Chuguang Zheng State Key Laboratory of Coal Combustion,Huazhong University of Science and Technology,Wuhan 430074,China | 2010 | Journal of Environmental Sciences2010，22，10： | 15 |
| 8 | Targeting cancer stem cell pathways for cancer therapy显示文摘Since cancer stem cells(CSCs)were first identified in leukemia in 1994,they have been considered promising therapeutic targets for cancer therapy.These cells have self-renewal capacity and differentiation potential and contribute to multiple tumor malignancies,such as recurrence,metastasis,heterogeneity,multidrug resistance,and radiation resistance.The biological activities of CSCs are regulated by several pluripotent transcription factors,such as OCT4,Sox2,Nanog,KLF4,and MYC.In addition,many intracellular signaling pathways,such as Wnt,NF-κB(nuclear factor-κB),Notch,Hedgehog,JAK-STAT(Janus kinase/signal transducers and activators of transcription),PI3K/AKT/mTOR(phosphoinositide 3-kinase/AKT/mammalian target of rapamycin),TGF(transforming growth factor)/SMAD,and PPAR(peroxisome proliferator-activated receptor),as well as extracellular factors,such as vascular niches,hypoxia,tumor-associated macrophages,cancer-associated fibroblasts,cancer-associated mesenchymal stem cells,extracellular matrix,and exosomes,have been shown to be very important regulators of CSCs.Molecules,vaccines,antibodies,and CAR-T(chimeric antigen receptor T cell)cells have been developed to specifically target CSCs,and some of these factors are already undergoing clinical trials.This review summarizes the characterization and identification of CSCs,depicts major factors and pathways that regulate CSC development,and discusses potential targeted therapy for CSCs. | Liqun Yang Pengfei Shi Gaichao Zhao Jie Xu Wen Peng Jiayi Zhang Guanghui Zhang Xiaowen Wang Zhen Dong Fei Chen Hongjuan Cui | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 12 |
| 9 | Design and test of tray-seedling sorting transplanter显示文摘In order to improve the automatic sorting and transplanting of tray-seedling and reduce labors strength,a new sorting transplanter was designed.According to the feature of normal seedling tray and manual grading method,the mechanical sorting procedure was defined.The key parts of sorting transplanter are as follows:an efficient transfer mechanism with aerodynamic buffer,a seedling identifying and measuring unit based on linear-structured vision,the extendible multi-grasper with wireless technology and the system controller.The experiments were conducted and showed that the transplanting success rate was 90.0% on the tray of 6×12 holes under the speed of 700 cycles per hour.The vision unit’s failed identifying rate for the superior pepper seedlings on five different trays was less than 10%,and the measurement error of seedling height was about 5 mm. | Feng Qingchun Zhao Chunjiang Jiang Kai Fan Pengfei Wang Xiu | 2015 | International Journal of Agricultural and Biological Engineering2015，8，2： | 12 |
| 10 | Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China显示文摘The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls;the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza. | Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen | 2022 | Science China(Life Sciences)2022，65，4： | 12 |
| 11 | The levels, sources and reactivity of volatile organic compounds in a typical urban area of Northeast China显示文摘Air concentrations of volatile organic compounds(VOCs) were continually measured at a monitoring site in Shenyang from 20 August to 16 September 2017. The average concentrations of alkanes, alkenes, aromatics and carbonyls were 28.54, 6.30, 5.59 and9.78 ppbv, respectively. Seven sources were identified by the Positive Matrix Factorization model based on the measurement data of VOCs and CO. Vehicle exhaust contributed the most(36.15%) to the total propene-equivalent concentration of the measured VOCs,followed by combustion emission(16.92%), vegetation emission and secondary formation(14.33%), solvent usage(10.59%), petrochemical industry emission(9.89%), petrol evaporation(6.28%), and liquefied petroleum gas(LPG) usage(5.84%). Vehicle exhaust, solvent usage and combustion emission were found to be the top three VOC sources for O_3 formation potential, accounting for 34.52%, 16.55% and 11.94%, respectively. The diurnal variation of the total VOCs from each source could be well explained by their emission characteristics,e.g., the two peaks of VOC concentrations from LPG usage were in line with the cooking times for breakfast and lunch. Wind rose plots of the VOCs from each source could reveal the possible distribution of the sources around the monitoring site. The O_3 pollution episodes during the measurement period were found to be coincident with the elevation of VOCs, which was mainly due to the air parcel from the southeast direction where petrochemical industry emission was found to be dominant, suggesting that the petrochemical industry emission from the southeast was probably a significant cause of O_3 pollution in Shenyang. | Zhuobiao Ma Chengtang Liu Chenglong Zhang Pengfei Liu Can Ye Chaoyang Xue Di Zhao Jichen Sun Yiming Du Fahe Chai Yujing Mu | 2019 | Journal of Environmental Sciences2019，31，5： | 12 |
| 12 | A Statistical Analysis of China's Traffic Tunnel Development Data显示文摘 | Yong Zhao Pengfei Li | 2018 | Engineering2018，4，1： | 11 |
| 13 | Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone marrowderived macrophage显示文摘Macrophages play critical roles in renal fibrosis.However,macrophages exhibit ontogenic and functional heterogeneities,and which population of macrophages contributes to renal fibrosis and the underlying mechanisms remain unclear.In this study,we genetically targeted Notch signaling by disrupting the transcription factor recombination signal binding protein-JK(RBP-J),to reveal its role in regulation of macrophages during the unilateral ureteral obstruction(UUO)-induced murine renal fibrosis.Myeloid-specific disruption of RBP-J attenuated renal fibrosis with reduced extracellular matrix deposition and myofibroblast activation,as well as attenuated epithelial-mesenchymal transition,likely owing to the reduced expression of TGF-β.Mean while,RBP-J deletion significantly hampered macrophage infiltration and activation in fibrotic kidney,although their proliferation appeared unaltered.By using macrophage clearance experiment,we found that kidney resident macrophages made negligible contribution,but bone marrow(BM)-derived macrophages played a major role in renal fibrogenesis.Further mechanistic analyses showed that Notch blockade reduced monocyte emigration from BM by down-regulating CCR2 expression.Finally,we found that myeloid-specific Notch activation aggravated renal fibrosis,which was mediated by CCR2^+macrophages infiltration.In summary,our data have unveiled that myeloid-specific targeting of Notch could ameliorate renal fibrosis by regulating BM-derived macrophages recruitment and activation,providing a novel strategy for intervention of this disease. | Yali Jiang Yuanyuan Wang Pengfei Ma Dongjie An Junlong Zhao Shiqian Liang Yuchen Ye Yingying Lu Peng Zhang Xiaowei Liu Hua Han Hongyan Qin | 2019 | Protein & Cell2019，10，3： | 10 |
| 14 | Two-photon-excited near-infrared emissive carbon dotsas multifunctional agents for fluorescence imaging andphotothermal therapy显示文摘C dots (CDs) have shown great potential in bioimaging and phototherapy.However, it is challenging to manipulate their fluorescent properties andtherapeutic efficacy to satisfy the requirements for clinic applications. In thisstudy, we prepared S, Se-codoped CDs via a hydrothermal method anddemonstrated that the doping resulted in excitation wavelength-independentnear-infrared (NIR) emissions of the CDs, with peaks at 731 and 820 nm.Significantly, the CDs exhibited a photothermal conversion efficiency of -58.2%,which is the highest reported value for C nanostructures and is comparable tothat of Au nanostructures. Moreover, the CDs had a large two-photon absorptioncross section (-30,045 GM), which allowed NIR emissions and the photothermalconversion of the CDs through the two-photon excitation (TPE) mechanism. Invitro and in vivo tests suggested that CDs can function as new multi functionalphototheranostic agents for the TPE fluorescence imaging and photothermaltheraov of cancer cells. | Minhuan Lan Shaojing Zhao Zhenyu Zhang Li Yan Liang Guo Guangle Niu Jinfeng Zhang Junfang Zhao Hongyan Zhang Pengfei Wang Guangyu Zhu Chun-Sing Lee Wenjun Zhang | 2017 | Nano Research2017，10，9： | 9 |
| 15 | Outbreak of human astrovirus 1 lineage 1d in a childcare center in China显示文摘Dear Editor,Astrovirus is an enteric virus associated with sporadic diarrhea or large outbreaks of gastroenteritis(Mendez et al.,2013).Until 2008,human astroviruses(HAst Vs)were classified into eight serotypes—HAstV-1 to HAstV-8—based on the reactivity of their capsid protein with type-specific antibodies.Among these serotypes,HAstV-1is the most prevalent globally.However,some divergent new astroviruses(MLB1/MLB2,VA1/VA2/VA3,and HMO A/B/C)have been discovered recently in | Meiling Hou Xuexue Liang Liqian Tan Pengfei Liu Wei Zhao | 2016 | Virologica Sinica2016，31，3： | 9 |
| 16 | LICOM Model Datasets for the CMIP6 Ocean Model Intercomparison Project显示文摘The datasets of two Ocean Model Intercomparison Project(OMIP)simulation experiments from the LASG/IAP Climate Ocean Model,version 3(LICOM3),forced by two different sets of atmospheric surface data,are described in this paper.The experiment forced by CORE-II(Co-ordinated Ocean–Ice Reference Experiments,Phase II)data(1948–2009)is called OMIP1,and that forced by JRA55-do(surface dataset for driving ocean–sea-ice models based on Japanese 55-year atmospheric reanalysis)data(1958–2018)is called OMIP2.First,the improvement of LICOM from CMIP5 to CMIP6 and the configurations of the two experiments are described.Second,the basic performances of the two experiments are validated using the climatological-mean and interannual time scales from observation.We find that the mean states,interannual variabilities,and long-term linear trends can be reproduced well by the two experiments.The differences between the two datasets are also discussed.Finally,the usage of these data is described.These datasets are helpful toward understanding the origin system bias of the fully coupled model. | Pengfei LIN Zhipeng YU Hailong LIU Yongqiang YU Yiwen LI Jirong JIANG Wei XUE Kangjun CHEN Qian YANG Bowen ZHAO Jilin WEI Mengrong DING Zhikuo SUN Yaqi WANG Yao MENG Weipeng ZHENG Jinfeng MA | 2020 | Advances in Atmospheric Sciences2020，37，3： | 9 |
| 17 | Dual-Mode Induction of Tunable Circularly Polarized Luminescence from Chiral Metal-Organic Frameworks显示文摘The general approach for fabricating solid-state materials showing circularly polarized luminescence(CPL)is still in its challenge.In this work,chiral metal-organic frameworks(MOFs)with full-color and white-color circularly polarized light emission are firstly achieved through a host-guest emitter-loading strategy.Chiral zeolitic imidazolate frameworks(ZIFs,a class of MOFs)are fabricated by a facile and simple mixed-ligand coassembly pathway.Meantime,achiral dyes,quantum dots(QDs),and upconversion nanoparticles(UCNPs)are easily loaded into the chiral ZIFs during the synthetic process.Size-matched dyes can be solely encapsulated into the chiral cages of ZIF,resulting in induced CPL and enhanced luminescence efficiency in solid-state ZIF⊃dye composites.Large-sized QDs,after embedding into the gap of the ZIF particles,also exhibited intense CPL activity.Furthermore,through modulating the blending ratio of colored dyes or QDs in chiral ZIFs,white light-emitting ZIFs with circular polarization could be constructed in a solid state.In addition,through loading rare earth element-based upconversion nanoparticles(UCNPs)into chiral ZIFs,upconverted CPL(UC-CPL)could be achieved with a high dissymmetry factor(glum).Thus,various achiral luminophores were endowed with CPL upon coupling with chiral ZIFs,which significantly deepened and enlarged the research scope of the chiroptical materials in a solid state. | Tonghan Zhao Jianlei Han Xue Jin Minghao Zhou Yan Liu Pengfei Duan Minghua Liu | 2020 | Research2020，，1： | 8 |
| 18 | Safety and efficacy of stent-assisted coiling for acutely ruptured wide-necked intracranial aneurysms:comparison of LVIS stents with laser-cut stents显示文摘Background:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients with acutely ruptured wide-necked intracranial aneurysms treated with LVIS stent-assisted coiling(LVIS stent group)and laser-cut stent-assisted coiling(laser-cut stent group)were retrospectively reviewed from January 2014 to December 2017.Propensity score matching was used to adjust for potential differences in age,sex,aneurysm location,aneurysm size,neck width,Hunt-Hess grade,and modified Fisher grade.Perioperative procedure-related complications and clinical and angiographic follow-up outcomes were compared.Univariate and multivariate analyses were performed to determine the associations between procedure-related complications and potential risk factors.Results:A total of 142 patients who underwent LVIS stent-assisted coiling and 93 patients who underwent laser-cut stent-assisted coiling were enrolled after 1:2 propensity score matching.The angiographic follow-up outcomes showed that the LVIS stent group had a slightly higher complete occlusion rate and lower recurrence rate than the laser-cut stent group(92.7%vs 80.6%;3.7%vs 9.7%,P=0.078).The clinical outcomes at discharge and follow-up between the two groups demonstrated no significant differences(P=0.495 and P=0.875,respectively).The rates of intraprocedural thrombosis,postprocedural thrombosis,postoperative early rebleeding,and procedure-related death were 0.7%(1/142),1.4%(2/142),2.8%(4/142),and 2.1%(3/142)in the LVIS stent group,respectively,and 4.3%(4/93),2.2%(2/93),1.1%(1/93),and 3.2%(3/93)in the laser-cut stent group,respectively(P=0.082,0.649,0.651,and 0.683).Nevertheless,the rates of overall procedure-related complications and intraprocedural rupture in the LVIS stent group were significantly lower than those in the laser-cut stent group(5.6%vs 14.0%,P=0.028;0.7%vs 6.5%,P=0.016).Multivariate analysis showed that laser-cut stent-assisted coiling was an independent predictor for overall procedurerelated complications(OR=2.727,P=0.037);a history of diabetes(OR=7.275,P=0.027)and other cerebrovascular diseases(OR=8.083,P=0.022)were independent predictors for ischemic complications,whereas none of the factors were predictors for hemorrhagic complications.Conclusions:Compared with laser-cut stent-assisted coiling,LVIS stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms could reduce the rates of overall procedure-related complications and intraprocedural rupture. | Gaici Xue Qiao Zuo Xiaoxi Zhang Haishuang Tang Rui Zhao Qiang Li Yibin Fang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu | 2021 | Chinese Neurosurgical Journal2021，7，2： | 8 |
| 19 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 20 | Long-term treadmill exercise inhibits neuronal cell apoptosis and reduces tau phosphorylation in the cerebral cortex and hippocampus of aged rats显示文摘Aging is an inevitably spontaneous process of the creature.With the increase of age,physical function is degraded in the elderly.One of the most common degradation is memory loss and cognitive impairment in brain function.Neuron loss and neurofibrillary tangles formation contributes to brain dysfunction.Neuron loss is associated with neuronal cell apoptosis.Apoptosis is a process | Guoliang Fang Jiexiu Zhao Pengfei Li Liang Li Tao Yu Xingya Yang Zihong He Ye Tian | 2017 | Science Bulletin2017，62，11： | 7 |
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