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| 1 | Recent trends in liver transplantation for alcoholic liver disease in the United States显示文摘AIM To examine temporal changes in the indications for liver transplantation(LT) and characteristics of patients transplanted for alcoholic liver disease(ALD).METHODS We performed a retrospective cohort analysis of trends in the indication for LT using the United Network for Organ Sharing(UNOS) database between 2002 and 2015. Patients were grouped by etiology of the liver disease and characteristics were compared using χ~2 and t-tests. Time series analysis was used identifying any year with a significant change in the number of transplants per year for ALD, and before and after eras were modeled using a general linear model. Subgroup analysis of recipients with ALD was performed by age group, gender, UNOS region and etiology(alcoholic cirrhosis, alcoholic hepatitis and hepatitis C-alcoholic cirrhosis dual listing).RESULTS Of 74216 liver transplant recipients, ALD(n = 9400, 12.7%) was the third leading indication for transplant after hepatitis C and hepatocellular carcinoma. Transplants for ALD, increased from 12.8%(553) in 2002 to 16.5%(1020) in 2015. Time series analysis indicated a significant increase in the number of transplants per year for ALD in 2013(P = 0.03). There were a stable number of transplants per year between 2002 and 2012(linear coefficient 3, 95%CI:-4.6, 11.2) an increase of 177 per year between 2013 and 2015(95%CI: 119, 234). This increase was significant for all age groups except those 71-83 years old, was observed for both genders, and was incompletely explained by a decrease in transplants for hepatitis C and ALD dual listing. All UNOS regions except region 9 saw an increase in the mean number of transplants per year when comparing eras, and this increase was significant in regions 2, 3, 4, 5, 6, 8, 10 and 11.CONCLUSION There has been a dramatic increase in the number of transplants for ALD starting in 2013. | Catherine E Kling James D Perkins Robert L Carithers Dennis M Donovan Lena Sibulesky | 2017 | World Journal of Hepatology2017,9,36: | 6 |
| 2 | 术前检测患者血液中总蛋白、白蛋白与白细胞介素-1受体拮抗剂作为切口疝修补术后是否出现血清肿的预测指标显示文摘患者切口疝修补术后出现血清肿是非常常见的,约占20%~30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,甚至是手术治疗都是必要的。 | Klink CD Binnebosel M Lucas AH Schachtrupp A Grommes J Conze J Klinge U Neumann U Junge K 宗振(译) 陈双(校) | 2012 | 中华疝和腹壁外科杂志(电子版)2012,6,2: | 2 |
| 3 | Preoperative acute hype-rvolemic hemodilution with hyolroxyethylstarch:an alternative to acute normovolemic hemodilution显示文摘 | Mielke LL Entholzner EK Kling M | 1997 | Anesth Analg1997,84,: | 1 |
| 4 | Molecular characterization of two strains of the avian adeno-associated virus (AAAV) 显示文摘 | Hess M Paul G Kling S | 1995 | Arch Virol1995,140,: | 1 |
| 5 | Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias 显示文摘 | Yarchoan M Xie SX Kling MA | 2012 | Brain2012,135,12: | 1 |
| 6 | Con trasting cardiac regional responses o A-type and B-type natri- uretic peptide to experimental chronic heart failure显示文摘 | HYSTAD M E KLINGE R SPURKLAND A | 2000 | Scand J Clin Lab Invest2000,60,4: | 1 |
| 7 | Utility of the shock index in predicting mortality in traumatically inj ured patients显示文摘 | CANNON C M BRAXTON C C KLING SMITH M | 2009 | J Trauma : Injury Infection and Critical Care2009,67,: | 1 |
| 8 | Age-related reference values for activation markers of the coagulation and fibrinolytic systems in children显示文摘 | Ries M Kling J Rauch R | 1997 | Thromb Res1997,85,4: | 1 |
| 9 | The plat-forms enabling wireless sensor networks 显示文摘 | HILL J HORTON M KLING R | 2004 | Communications of The ACM2004,47,6: | 1 |
| 10 | The importance of integration and scale in the arbuscular mycorrhizal symbiosis显示文摘 | Miller RM Kling M | 2000 | Plant and Soil2000,226,2: | 1 |
| 11 | New aspects on patients affected by dysferlin deficient muscular dystrophy 显示文摘 | Klinge L Aboumousa A Eagle M | 2010 | J Neurol Neurosurg Psychiatry2010,81,9: | 1 |
| 12 | The importance oI integration and scale in the arbuscular mycorrhizal symbiosis显示文摘 | MILLER R M KLING M | 2000 | Plant Soil2000,226,: | 1 |
| 13 | Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma显示文摘 | BELINSKY S A KLINGE D M LIECHTY K C | 2004 | Carcinogenesis2004,25,6: | 1 |
| 14 | High plasma levels of Nterminal pro -atrial natriuretic peptide associated with low anxiety in severe heart failure显示文摘 | Herrmann LC Binder L Klinge M | 2003 | Psychosom Med2003,65,4: | 1 |
| 15 | Distribution implications of environmental taxes in Denmark 显示文摘 | Klinge J H Birr-Pedersen K K Wier M | 2003 | Fiscal Studies2003,24,4: | 1 |
| 16 | Preoperative acute hypervolemic hemodi-lution with hydroxyethylstarch:an alter-native to acute normovolemic hemodilr-tion显示文摘 | Mielkell Entholzner EK Kling M | 1997 | AnesthAnalg1997,84,: | 1 |
| 17 | Effect of phenolic compounds and indole acetic acid on adventitious root initiation in cut- ting of Phaseolus aureus, Acer saccharinum and Acer seum显示文摘 | Kling G Meyer M | 1983 | Hort Sci1983,18,3: | 1 |
| 18 | Hybrid breeding in durum wheat:heterosis and combining ability显示文摘 | GOWDA M KLING C WRSCHUM T | 2010 | Crop Science2010,50,: | 1 |
| 19 | Application of three dimensional stereography to assess abdominal wall mobility 显示文摘 | Klinge U Mailer M Brticker C Schumpelick V | 1998 | Hernia1998,2,: | 1 |
| 20 | Adaptive Changes in the Self-Concept During A Life Transition显示文摘 | Kling K C Ryff C D Essex M J | 1997 | Personality and Social Psy- chology Bulletin1997,23,9: | 1 |