Valvular and perivalvular involvement in patients with chronic kidney disease

查看全文 作　　者：Neelavathi [1]Senkottaiyan;Saad [1]Hafidh;Farrin [1]A.Manian;Martin [1]A.Alpert 机构地区：[1]Department of Medicine St.John's Mercy Medical Center,St.Louis,MO 出　　处：《Journal of Geriatric Cardiology》索引2005年第2卷第3期,共6页 摘　　要：Abstract Mitral annular calcification (MAC) and aortic valve alcification (AVC) are the most common valvular and perivalvular bnormalities in patients with chronic kidney disease (CKD). Both MAC and AVC occur at a younger age in CKD patients than in the general population. AVC progresses to aortic stenosis and mild aortic stenosis progresses to severe aortic stenosis at a more rapid rate in patients with CKD than in the general population. The use of calcium-free phosphate binders in such patients may reduce the calcium burden in valvular and perivalvular tructures and retard the rate of progression of aortic stenosis. Despite high rates of morbidity and mortality, the prognosis associated with valve surgery in patients with CKD is better than without valve surgery. Infective endocarditis remains an important complication of CKD, particularly in those treated with hemodialysis. 关 键 词：Chronic kidney disease MITRAL annular CALCIFICATION AORTIC valve CALCIFICATION AORTIC STENOSIS INFECTIVE ENDOCARDITIS