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Endoscopic management of Dieulafoy's lesion using Isoamyl-2-cyanoacrylate

查看全文 作  者:Abd Elrazek M Aly Abd [1,2]Elrazek;Nakamura [3]Yoko;Moriguchi [3]Hiroki;Mohamed [1]Afify;Mohamed [2]Asar;Badr [4]Ismael;Magdy [2]Salah 高影响力作者 机构地区:[1]Medicine of Liver Transplantation, Department of Tropical Medicine, Faculty of Medicine, Al Azhar University;[2]Department of General Surgery and Endoscopy, Faculty of Medicine, Al Azhar University;[3]Department of Medical Informatics, Institute of Biomedical Science-University of Tokushima;[4]Department of Anesthesia and Intensive Care, Al Azhar University高影响力机构 出  处:《World Journal of Gastrointestinal Endoscopy》索引2013年第5卷第8期,共3页高影响力期刊 摘  要:Dieulafoy's lesion (DL) is a rare but important cause of obscure gastrointestinal bleeding that may be over-looked during diagnostic endoscopy. Mortality rates are similar to those of other causes for gastrointestinal bleeding. Diagnosis by upper endoscopy is the modal-ity of choice during acute bleeding. In the absence of active bleeding, the lesion resembles a raised nipple or visible vessel. There are no guidelines regarding effective selective therapy for DL, when diagnosed, en-doscopist experience is the major determinant of the treatment strategy. Following our strategy, an expert endoscopist with a skilled assistant should have a high rate of successful DL diagnosis when an obscured gas-trointestinal lesion is suspected. Cyanoacryltes com-pounds have been used successfully in management of Gastric varices and DLs. To our knowledge, there have been no previous reports regarding use of isoamyl-2-cyanoacrylate (AMCRYLATE ; Concord Drugs Ltd.,Hyderabad, India) as an effective therapy for gastric DL without serious complications. In our case study, Isoamyl-2-cyanoacrylate (AMCRYLATE) was effective and safe for treating DL. Surgical wedge resection of the lesion should be considered as a therapeutic option if endoscopic therapy fails. 关 键 词:Dieulafoy’s LESION Isoamyl-2-cyanoacrylate Gastrointestinal bleeding Endoscopy Stomach
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