Current oncologic applications of radiofrequency ablation therapies

查看全文 作　　者：Dhruvil R [1]Shah;Sari [2]Green;Angelina [1]Elliot;John P [3]McGahan;Vijay P [1]Khatri

机构地区：[1]Division of Surgical Oncology,Department of Surgery,University of California Davis;[2]Department of Surgery,Harbor-UCLA Medical Center;[3]Department of Radiology,University of California Davis

出　　处：《World Journal of Gastrointestinal Oncology》索引2013年第5卷第4期,共10页

摘　　要：Radiofrequency ablation (RFA) uses high frequency alternating current to heat a volume of tissue around a needle electrode to induce focal coagulative necrosis with minimal injury to surrounding tissues. RFA can be performed via an open, laparoscopic, or image guided percutaneous approach and be performed under general or local anesthesia. Advances in delivery mechanisms, electrode designs, and higher power generators have increased the maximum volume that can be ablated, while maximizing oncological outcomes. In general, RFA is used to control local tumor growth, prevent recurrence, palliate symptoms, and improve survival in a subset of patients that are not candidates for surgical resection. It's equivalence to surgical resection has yet to be proven in large randomized control trials. Currently, the use of RFA has been well described as a primary or adjuvant treatment modality of limited but unresectable hepatocellular carcinoma, liver metastasis, especially colorectal cancer metastases, primary lung tumors, renal cell carcinoma, boney metastasis and osteoid osteomas. The role of RFA in the primary treatment of early stage breast cancer is still evolving. This review will discuss the general features of RFA and outline its role in commonly encountered solid tumors. 关键词：RADIOFREQUENCY ablation Hepatocellular CARCINOMA COLORECTAL CANCER liver metastasis Lung CANCER Renal cell CARCINOMA

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Current oncologic applications of radiofrequency ablation therapies

参考文献(69)

引证文献(34)

耦合文献(243)

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