Hepatic reactive lymphoid hyperplasia in a patient with primary biliary cirrhosis

查看全文 作　　者：Mitsuaki [1]Ishida;Tamio [2]Nakahara;Yousuke [3]Mochizuki;Tomoyuki [2]Tsujikawa;Akira [2]Andoh;Yasuharu [3]Saito;Hiroshi [4]Yamamoto;Fumiyoshi [1]Kojima;Machiko [1]Hotta;Tohru [4]Tani;Yoshihide [2]Fujiyama;Hidetoshi [1]Okabe

机构地区：[1]Department of Clinical Laboratory Medicine and Division of Diagnostic Pathology,Shiga University of Medical Sci ence,Otsu,Shiga 520-2192,Japan;[2]Department of Gastroenterology,Shiga University of Medical Science,Otsu,Shiga 520-2192,Japan;[3]Division of Endoscopy,Shiga University of Medical Science,Otsu,Shiga 520-2192,Japan;[4]Department of Surgery,Shiga University of Medical Science,Otsu,Shiga 520-2192,Japan

出　　处：《World Journal of Hepatology》索引2010年第2卷第10期,共5页

摘　　要：Reactive lymphoid hyperplasia(RLH) of the liver is an extremely rare lesion characterized by the proliferation of non-neoplastic lymphocytes forming follicles.Hepatic RLH is known to be associated with gastrointestinal carc inoma and autoimmune diseases including primary biliary cirrhosis(PBC).We report a case of hepatic RLH in a patient with PBC and gastric cancer.A 68 year old Japanese woman with a 10 year history of liver enzyme abnormality was admitted.Laboratory testing revealed that her anti-mitochondrial antibody was markedly elev ated.Five mo after the diagnosis of PBC,she was foun d to have gastric cancer.Abdominal computed tom og raphy disclosed a liver nodule in S8,suggesting metas tatic gastric carcinoma.Histopathologically,the resected liver lesion comprised of a nodular proliferation of small lym phocytes with lymphoid follicles.This is the first reported case of hepatic RLH in a patient with both PBC and gastric cancer.Pre-operative diagnosis of hepatic RLH by clinical imaging is extremely difficult.Therefore,a need le biopsy could be useful to make a diagnosis of hepat ic RLH,especially to differentiate from metastatic gastroin t estinal carcinoma. 关键词：Reactive LYMPHOID HYPERPLASIA PSEUDOLYMPHOMA Liver Primary BILIARY CIRRHOSIS Gastric cancer

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Hepatic reactive lymphoid hyperplasia in a patient with primary biliary cirrhosis

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