Alpha-fetoprotein specific CD4 and CD8 T cell responses in patients with hepatocellular carcinoma

查看全文 作　　者：Shahriar [1]Behboudi;Stephen P [1]Pereira

机构地区：[1]UCL Institute of Hepatology,University College London,Royal Free Hospitals

出　　处：《World Journal of Hepatology》索引2010年第2卷第7期,共5页

基　　金：Supported by a project grant from Association for International Cancer Research 摘　　要：The presence of CD8 T cell responses to tumor associated antigens have been reported in patients with different malignancies. However, there is very little inf ormation on a comparable CD8 and CD4 T cell response to a tumor antigen in liver cancer patients. Here, we re-examine the kinetic and the pattern of T helper 1 and cytotoxic T lymphocyte responses to alpha-fetoprotein (AFP),a tumor rejection antigen in hepatocellular carcinoma (HCC). Then, we discuss the possibility of using AFP-based immunotherapy in combination with necrotizing treatments in HCC patients. 关键词：HEPATOCELLULAR carcinoma ALPHA-FETOPROTEIN Cell-mediated IMMUNITY IMMUNOTHERAPY

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Alpha-fetoprotein specific CD4 and CD8 T cell responses in patients with hepatocellular carcinoma

参考文献(42)

引证文献(10)

耦合文献(4)

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