Obesity and non-alcoholic fatty liver disease: Disparate associations among asian populations

查看全文 作　　者：Robert J [1]Wong;Aijaz [1]Ahmed

机构地区：[1]Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine

出　　处：《World Journal of Hepatology》索引2014年第6卷第5期,共11页

摘　　要：obesity is a global epidemic contributing to an increas-ing prevalence of obesity-related systemic disorders, including nonalcoholic fatty liver disease. The rising prevalence of nonalcoholic steatohepatitis(NASh) will in the near future lead to end-stage liver disease in a large cohort of patients with NASh-related cirrhosis and NASh is predicted to be a leading indication for liver transplantation in the coming decade. however, the prevalence of obesity and the progression of hepatic histological damage associated with NASh exhibit sig-nificant ethnic disparities. Despite a significantly lower body mass index and lower rates of obesity compared to other ethnic groups, Asians continue to demonstrate a significant prevalence of hypertension, diabetes, met-abolic syndrome and NASh. Ethnic disparities in central adiposity and visceral fat distribution have been hy-pothesized to contribute to these ethnic disparities. The current review focuses on the epidemiology of obesity and NASh among Asian populations. 关键词：Non-alcoholic FATTY liver disease Non-alcoholic STEATOHEPATITIS OBESITY metabolic syndrome Asians hepatocellular carcinoma

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Obesity and non-alcoholic fatty liver disease: Disparate associations among asian populations

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