Benefit of stem cells and skeletal myoblast cells in dilated cardiomyopathies

查看全文 作　　者：Luiz César Guarita-[1]Souza;Júlio César [1]Francisco;Rossana [1]Simeoni;Jose Rocha Faria-[1]Neto;Katherine Athayde Teixeira de [2]Carvalho

机构地区：[1]Department of Post Graduation Surgery,Pontifical Catholic University of Parana;[2]The PeléPequeno Príncipe Institute,Child and Adolescent Health Research and Pequeno Príncipe Faculty

出　　处：《World Journal of Cardiology》索引2011年第3卷第3期,共5页

摘　　要：Although some authors suggest that there is mitotic division in the heart,most cardiomyocytes do not have the capacity to regenerate after myocardial infarction and when this occurs there is a deterioration of contractile function,and if the area of infarction is extensive ventricular remodeling may occur,leading to the development of heart failure.Cell transplantation into the myocardium with the goal of recovery of cardiac function has been extensively studied in recent years. The effects of cell therapy are based directly on the cell type used and the type of cardiac pathology.For myocardial ischemia in the hibernating myocardium, bone marrow cells have functional benefits,however these results in transmural fibrosis are not evident. In these cases there is a benefit of implantation with skeletal myoblasts,for treating the underlying cause of disease,the loss of cell contractility. 关键词：Cell transplantation CARDIOMYOPATHY SKELETAL MYOBLASTS Stem CELLS

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Benefit of stem cells and skeletal myoblast cells in dilated cardiomyopathies

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