Primary hepatic neuroendocrine carcinoma:clinical analysis of 11 cases

查看全文 作　　者：Huang, Yang-[1]Qing;Xu, [1]Feng;Yang, Jia-[1]Mei;Huang, [2]Bin

机构地区：[1]Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Special Treatment & Liver Transplantat, Shanghai 200438, Peoples R China;[2]Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Radiol, Shanghai 200438, Peoples R China;

出　　处：《Hepatobiliary & Pancreatic Diseases International》索引2010年第9卷第1期,共5页

摘　　要：BACKGROUND:Primary hepatic neuroendocrine carcinoma (PHNEC) is extremely rare,and fewer than 300 cases have been reported in the English/Chinese-language literature,therefore it is difficult to make a proper diagnosis and determine a therapeutic approach.METHODS:Eleven PHNEC patients were admitted to our hospital between January 1996 and May 2008.Laboratory examination,digestive endoscopy,B-ultrasonography,CT,MRI,or PET-CT were performed on the patients for preoperative diagnosis.All patients received liver resection.Some patients received transcatheter arterial chemoembolization (TACE),percutaneous ethanol injection treatment (PEIT),or octreotide injection when a recurrence was found.The patients' clinical data were recorded and all patients were followed up.RESULTS:The patients were confirmed pathologically as having PHNEC.Their median follow-up time was 33 months (12-107 months).All patients survived,and the longest postoperative survival time was 107 months,the longest diseasefree survival time was 98 months,the 1-year survival rate was 100%,and the 1-year recurrence rate was 45.5% (5/11).CONCLUSIONS:Since PHNEC is easy to confuse with hepatocellular carcinoma,careful screening of symptoms is needed to avoid misdiagnosis.Resection is the first choice of treatment for PHNEC and provides the most favorable outcomes including long-term survival.Other treatment such as TACE and PEIT can be considered as well,especially when a tumor recurs. 关键词：carcinoma,neuroendocrine CARCINOID tumor LIVER NEOPLASMS LIVER RESECTION

相关文献

参考文献（22）
引证文献（37）
耦合文献（2）

参考文献(22)

引证文献(37)

耦合文献(2)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Primary hepatic neuroendocrine carcinoma:clinical analysis of 11 cases

参考文献(22)

引证文献(37)

耦合文献(2)

用户提示