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Protective effect of Eleteria cardamomum(L.) Maton against Pan masala induced damage in lung of male Swiss mice

查看全文 作  者:Sweety [1]Kumari;Abhijit [1]Dutta 高影响力作者 机构地区:[1]University Department of Zoology.Ranchi University,Ranchi-834008.India高影响力机构 出  处:《Asian Pacific Journal of Tropical Medicine》索引2013年第6卷第7期,共7页高影响力期刊 摘  要:Objective:To study the potential ameliorating properties of cardamom Elettaria cardamomum (E.cardamomum) L.Maton against pan masala induced damage in lung of male Swiss mice. Methods:The experimental animals were divided into 3 groups(control,pan masala treated group and pan masala with cardamom treated group) to evaluate pan masala toxicity.The observations were substantiated with profound changes in the lung tissue as revealed in the histologic and transmission electron microscopic examinations.Results:Lung of pan masala treated group showed adenocarcinoma,edema,and inflammation with increased activity of acid phosphatase,alkaline phosphatase,and lactate dehydrogenase.The deleterious effects were seen to be less in cardamom treated group and the enzymatic activity also decreased significantly (P<0.05)\ in the ameliorating group.Conclusions:Thus,the present experiment exciting results are observed when cardamom is supplemented with pan masala,or when given alone. 关 键 词:PAN masala TOXICITY LUNG AMELIORATION CARDAMOM
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