In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants

查看全文 作　　者：Binit [1]Shrestha;M.L.Srithavaj [1]Theerathavaj;Sroisiri [2]Thaweboon;Boonyanit [2]Thaweboon

机构地区：[1]Maxillofacial Prosthetic Service,Faculty of Dentistry,Mahidol University;[2]Department of Oral Microbiology,Faculty of Dentistry,Mahidol University

出　　处：《Asian Pacific Journal of Tropical Biomedicine》索引2012年第2卷第10期,共4页

摘　　要：Objective:To determine the antimicrobial effects of grape seed on peri-implantitis microflora.Methods:The grape seed extract was tested against peri-implantitis microflora most commonly found in craniofacial implants including reference strains of Staphylococcus aureus(S.aureus),Escherichia coli(E.coli),Candida albicans(C.albicans)and clinical strains of S.aureus,Klebsiella pneumonia(K.pneumonia)and Candida parapsilosis(C.parapsilosis)by disk diffusion test.Minimum inhibitory concentrations(MIC)and minimum cidal concentrations(MCC)were determined using modified agar dilution millpore method.The extract was further combined with polyethylene glycol and propylene glycol,and was tested for antimicrobial effects.Results:Grape seed extract showed positive inhibitory effects with S.aureus at MIC of 0.625 mg/mL and MCC of1.25 mg/mL respectively.However the extracts showed minimal or no reactivity against strains of E.coli,K.pneumonia,C.parapsilosis and C.albicans.The use of grape seed extract in combination with polyethylene glycol and propylene glycol also showed dose dependent inhibitory effect on S.aureus.Conclusions:The results of the study showed that grape seed has potential antimicrobial effects which can be further studied and developed to be used in the treatment of infected skinabutment interface of craniofacial implants. 关键词：PERI-IMPLANTITIS Grape seed extract CRANIOFACIAL IMPLANTS STAPHYLOCOCCUS AUREUS

相关文献

参考文献（13）
引证文献（1）
耦合文献（0）

参考文献(13)

引证文献(1)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants

参考文献(13)

引证文献(1)

用户提示