Immunological alterations in hepatitis C virus infection

查看全文 作　　者：Vincenza [1]Calvaruso;Antonio [1]Craxì

机构地区：[1]Gastroenterologia and Epatologia,DIBIMIS,Università di Palermo,90127 Palermo,Italy

出　　处：《World Journal of Gastroenterology》索引2013年第19卷第47期,共8页

摘　　要：A higher prevalence of immunological processes has recently been reported in patients with hepatitis C virus(HCV)infection,focusing the attention of physicians and researchers on the close association between HCV and immune disorders.HCV lymphotropism represents the most important step in the pathogenesis of virusrelated immunological diseases and experimental,virologic,and clinical evidence has demonstrated a trigger role for HCV both in systemic autoimmune diseases,such as rheumatoid arthritis,Sj?gren syndrome,hemolytic anemia and severe thrombocytopenia,and in organ-specific autoimmune diseases,such as autoimmune hepatitis,thyroid disorders and diabetes.This review will outline the principal aspects of such HCVinduced immunological alterations,focusing on the prevalence of these less characterized HCV extrahepatic manifestations. 关键词：Hepatitis C virus Immune DISORDERS CYTOPENIA EXTRAHEPATIC MANIFESTATION AUTOANTIBODY

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Immunological alterations in hepatitis C virus infection

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