Exacerbation of Soft Tissue Lesions in Lead Exposed Virus Infected Mice

查看全文 作　　者：[1]PRATIBHAGUPTA;[1]M.M.HUSAIN;[1]RAVISHANKERt;[1]R.K.S.DOGRA;[1]P.K.SETH;[2]R.K.MAHESHWARI;[1]PRATIBHAGUPTAt 机构地区：[1]VirologyLaboratory,IndustrialToxicologyResearchCentre,P.O.BoxNo.80,MahatmaGandhiMarg,Lucknow226001,lndia;[2]DepartmentofPathology,UniformedServicesUniversityofHealthSciences,4301JonesBridgeRoad,Bethesda,MD20814,USA 出　　处：《Biomedical and Environmental Sciences》索引2003年第16卷第4期,共10页 基　　金：This work was supported by US India Fund for Cultural and Scientific Cooperation under project No.N-904-660. 摘　　要：Objective To investigate the effect of Lead (Pb) acetate exposure on Semliki forest virus (SFV)pathogenesis in mice. Methods Different doses (62.5, 125, 250 and 500 mg/Kg body weight) of Pb dissolved in normal saline were given to mice by oral intubation in a sub-acute (28 days) 关 键 词：软组织损伤 醋酸盐 致病性 SFV 发病机理 动物实验 病毒感染 小鼠