巴贝多眼科研究中9年期间糖尿病视网膜病变的发病率

查看全文 作　　者：Leske M. [2]C.;Wu S. -[1]Y.;Hennis [1]A.;曹绪胜(译)[1] 机构地区：[1]不详;[2]Department of Preventive Medicine, Stony Brook University, L3 HSC, Stony Brook, NY 11794-8036, United States 出　　处：《世界核心医学期刊文摘(眼科学分册)》索引2006年第2卷第6期,共1页 摘　　要：Objective: To estimate the 9-year incidence of diabetic retinopathy (DR) in a population with the same ancestry as African Americans. Methods: Participants with diabetes mellitus and gradable photographs at the 9-year examination were evaluated (n=436). The incidences of minimum/moderate/severe DR,clinically significant macular edema (CSME),and sight threatening DR (severe DR plus CSME) were defined by the development of specific diabetic changes in persons without those conditions at baseline. Progression was defined as the development of severe/proliferative DR in persons with minimum/ moderate DR at baseline. Results: The 9-year DR incidence was 39.6% (38.0% for minimum,9.0% for moderate,and 2.6% for severe/proliferative DR). Incidence tended to increase with diabetes duration and treatment. Of persons with preexisting DR at baseline,8.2% progressed to proliferative DR. The CSME incidence was 8.7% ,and it increased with diabetes duration,accounting for most of the overall incidence of sight-threatening DR. Conclusions: The study provides new data on long-term incidence among persons of African origin. Results suggest a possible lower risk of severe/proliferative DR than in whites,while CSME incidence seems comparable or higher. The main component of sight-threatening DR was CSME,highlighting the importance of DR as a cause of vision loss in this population. 关 键 词：糖尿病视网膜病变(DR) 发病率 眼科研究 年期 糖尿病患者 视力丧失 美国人群 病程延长 糖尿病病程 增殖性