Autoimmune pancreatitis associated with a large pancreatic pseudocyst

查看全文 作　　者：Thilo [1]Welsch;Jrg [1]Kleeff;Irene [2]Esposito;Markus W [1]Büchler;Helmut [1]Friess

机构地区：[1]Department of Surgery, University of Heidelberg, Heidelberg, Germany;[2]Department of Pathology, University of Heidel-berg, Heidelberg, Germany

出　　处：《World Journal of Gastroenterology》索引2006年第12卷第36期,共3页

摘　　要：Pancreatic cystic lesions comprise various entities with different histopathological characteristics and their dif-ferential diagnosis is often a challenge for clinicians. Autoimmune pancreatitis (AIP) is usually not considered in the differential diagnosis of cystic lesions, but often mimics the morphological aspects of pancreatic neo-plasm. We report the case of a 64-year-old male patient with a cystic pancreatic head lesion (diameter 5 cm) and stenosis of the distal bile duct requiring repeated stent-ing. Because of the clinical presentation together with moderate elevation of serum CA19-9 and massive eleva-tion of cyst fluid CA19-9 (122.695 U/L; normal range: < 37.0 U/L), the patient underwent explorative laparotomy and pylorus preserving partial pancreaticoduodenectomy. Histology revealed surprisingly AIP with an inflammatory pseudocyst. In conclusion, cyst fluid analysis of tumor markers and cyst fluid cytology lack high accuracy to clearly differentiate cystic pancreatic lesions. Although AIP is rarely associated with pseudocysts, the disease has to be considered in the differential diagnosis of cys-tic pancreatic lesions. Early examination of serum IgG, IgG4 and auto-antibodies might save these patients from unnecessary endoscopical and surgical procedures. 关键词：自身免疫胰腺炎假性囊肿病理机制

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Autoimmune pancreatitis associated with a large pancreatic pseudocyst

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