Hypertriglyceridemia-induced pancreatitis: A case-based review

查看全文 作　　者：S Ian [1]Gan;Alun L [1]Edwards;Christopher J [1]Symonds;Paul L [1]Beck

机构地区：[1]Division of Gastroenterology and Endocrinology, Foothills Hospital, University of Calgary, Calgary, Alberta, Canada

出　　处：《World Journal of Gastroenterology》索引2006年第12卷第44期,共6页

基　　金：Supported by Alberta Heritage Foundation for Medical Research and Canadian Institute of Health Research 摘　　要：Hypertriglyceridemia is an established cause of pancreatitis. In a case-based approach, we present a review of hypertriglyceridemia and how it can cause pancreatitis. We outline how to investigate and manage such patients. A 35 year old man presented to the emergency department with abdominal pain and biochemical evidence of acute pancreatitis. There was no history of alcohol consumption and biliary imaging was normal. The only relevant past medical history was that of mild hyperlipidemia, treated with diet alone. Physical exam revealed epigastric tenderness, right lateral rectus palsy, lipemia retinalis, bitemporal hemianopsia and a delay in the relaxation phase of his ankle reflexes. Subsequent laboratory investigation revealed marked hypertriglyceridemia and panhypopituarism. An enhanced CT scan of the head revealed a large suprasellar mass impinging on the optic chiasm and hypothalamus. The patient was treated supportively; thyroid replacement and lipid lowering agents were started. He underwent a successful resection of a craniopharyngioma. Post- operatively, the patient did well on hormone replacement therapy. He has had no further attacks of pancreatitis. This case highlights many of the factors involved in the regulation of triglyceride metabolism. We review the common causes of hypertriglyceridemia and the proposed mechanisms resulting in pancreatitis. The incidence and management of hypertriglyceridemia- induced pancreatitis are also discussed. 关键词：胰腺炎高血脂治疗方法症状

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Hypertriglyceridemia-induced pancreatitis: A case-based review

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