Computation of flow through the oesophagogastric junction

查看全文 作　　者：Barry P [1]McMahon;Karl D [2]Odie;Kenneth W [2]Moloney;Hans [3]Gregersen

机构地区：[1]Department of Medical Physics and Clinical Engineering,Adelaide and Meath Hospital Dublin, Incorporating the National Children’s Hospital, Tallaght, Dublin 24,Ireland;[2]IMed Centre, Department of Mechanical Engineering, Institute of Technology Tallaght, Dublin 24, Ireland;[3]Center for Visceral Biomechanics and Pain, Aalborg Hospital, Aalborg DK-9100, Denmark,IMed Centre, Institute of Technology, Tallaght, Dublin 24, Ireland

出　　处：《World Journal of Gastroenterology》索引2007年第13卷第9期,共5页

基　　金：Supported by a Science Foundation Ireland through the ETS Walton Visiting Professor Programme; a grant from the Higher Education Authority in Ireland 摘　　要：Whilst methods exist to indirectly measure the effects of increased flow or gastro-oesophageal refluxing, they cannot quantitatively measure the amount of acid travelling back up into the oesophagus during reflux, nor can they indicate the flow rate through the oesophagogastric junction (OGJ). Since OGJ dysfunction affects flow it seems most appropriate to describe the geometry of the OGJ and its effect on the flow. A device known as the functional lumen imaging probe (FLIP) has been shown to reliably measure the geometry of and pressure changes in the OGJ. FLIP cannot directly measure flow but the data gathered from the probe can be used to model flow through the junction by using computational flow dynamics (CFD). CFD uses a set of equations known as the Navier-Stokes equations to predict flow patterns and is a technique widely used in engineering. These equations are complex and require appropriate assumptions to provide simplifications before useful data can be obtained. With the assumption that the cross-sectional areas obtained via FLIP are circular, the radii of these circles can be obtained. A cubic interpolation scheme can then be applied to give a high-resolution geometry for the OGJ. In the case of modelling a reflux scenario, it can be seen that at the narrowest section a jet of fluid squirts into the oesophagus at a higher velocity than the fluid surrounding it. This jet has a maximum velocity of almost 2 ms-1 that occurs where the OGJ is at its narrowest. This simple prediction of acid ‘squirting’ into the oesophagusillustrates how the use of numerical methods can be used to develop a better understanding of the OGJ. This initial work using CFD shows some considerable promise for the future. 关键词：食管-胃结合部食物流流体动力学模型计算

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Computation of flow through the oesophagogastric junction

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