Treatment of hepatitis C virus infection

查看全文 作　　者：Kilian [1]Weigand;Wolfgang [1]Stremmel;Jens [1]Encke

机构地区：[1]University of Heidelberg, Department of Gastroenterology and Hepatology Im Neuenheimer Feld 410, Heidelberg 69120, Germany

出　　处：《World Journal of Gastroenterology》索引2007年第13卷第13期,共9页

摘　　要：Acute and chronic hepatitis C virus (HCV) infection remains a serious health problem worldwide, however, there has been advancement in the treatment of HCV infection due to standard treatment using pegylated interferon and ribavirin. The literature indicates that therapy for HCV is becoming more individualized. In addition to considering genotype and viral RNA levels before treatment, achievement of an early virologic response (EVR) and a rapid virologic response (RVR) is now possible during therapy. Moreover, problem patients, such as non-responders, relapsers, HIV or HBV co- infected patients, patients with liver cirrhosis, and pre- or post-liver transplantation patients are an increasing fraction of the patients requiring treatment. This article reviews the literature regarding standard treatments and problem patients with acute and chronic HCV infection. It also includes discussion on contraindications and side effects of treatment with interferon and ribavirin, as well as new drug development. 关键词：丙型肝炎病毒感染治疗 HCV急性感染 HCV慢性感染

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Treatment of hepatitis C virus infection

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