Evaluation of prognostic factors and scoring system in colonic perforation

查看全文 作　　者：Atsushi [1]Horiuchi;Yuji [1]Watanabe;Takashi [1]Doi;Kouichi [1]Sato;Syungo [1]Yukumi;Motohira [1]Yoshida;Yuji [1]Yamamoto;Hiroki [1]Sugishita;Kanji [1]Kawachi

机构地区：[1]Department of Surgery 2, Ehime University School of Medicine

出　　处：《World Journal of Gastroenterology》索引2007年第13卷第23期,共4页

摘　　要：AIM: To study the significance of scoring systems assessing severity and prognostic factors in patients with colonic perforation. METHODS: A total of 26 patients (9 men, 17 women; mean age 72.7 ± 11.6 years) underwent emergency operation for colorectal perforation in our institution between 1993 and 2005. Several clinical factors were measured preoperatively and 24 h postoperatively. Acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ), Mannheim peritonitis index (MPI) and peritonitis index of Altona (PIA Ⅱ) scores were calculated preoperatively. RESULTS: Overall postoperative mortality rate was 23.1% (6 patients). Compared with survivors, non- survivors displayed low blood pressure, low serum protein and high serum creatinine preoperatively, and low blood pressure, low white blood cell count, low pH, low PaO2/FiO2, and high serum creatinine postoperatively. APACHE Ⅱ score was significantly lower in survivors than in non-survivors (10.4 ± 3.84 vs 19.3 ± 2.87, P = 0.00003). Non-survivors tended to display high MPI score and low PIA Ⅱ score, but no signif icant difference was identif ied. CONCLUSION: Pre- and postoperative blood pressure and serum creatinine level appear related to prognosis of colonic perforation. APACHE Ⅱ score is most associated with prognosis and scores ≥ 20 are associated with signif icantly increased mortality rate. 关键词：结肠穿孔刮伤系统预兆因子症状

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Evaluation of prognostic factors and scoring system in colonic perforation

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